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- Title
Acetazolamide-induced weakness in paramyotonia congenita.
- Authors
Riggs, J E; Griggs, R C; Moxley, R T
- Abstract
Acetazolamide has been shown to be effective prophylaxis for both hypokalemic and hyperkalemic paralysis. A patient with paramyotonia congenita, a related disorder with myotonia and episodic weakness, was studied during treatment with acetazolamide. Athough the patient's myotonia was virtually abolished, severe quadriparesis was produced during each trial of acetazolamide. This response distinguished this patient's condition from other forms of familial periodic paralysis and suggests that acetazolamide may be deleterious to some patients with periodic paralysis.
- Publication
Annals of internal medicine, 1977, Vol 86, Issue 2, p169
- ISSN
0003-4819
- Publication type
Journal Article
- DOI
10.7326/0003-4819-86-2-169