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Title
The net clinical benefit of warfarin anticoagulation in atrial fibrillation.
Authors
Singer, Daniel E; Chang, Yuchiao; Fang, Margaret C; Borowsky, Leila H; Pomernacki, Niela K; Udaltsova, Natalia; Go, Alan S
Abstract
Guidelines recommend warfarin use in patients with atrial fibrillation solely on the basis of risk for ischemic stroke without antithrombotic therapy. These guidelines rely on ischemic stroke rates observed in older trials and do not explicitly account for increased risk for hemorrhage.
Publication
Annals of internal medicine, 2009, Vol 151, Issue 5, p297