Works matching DE "TUMOR microenvironment"

Results: 5000

CD24a knockout results in an enhanced macrophage- and CD8⁺ T cell-mediated anti-tumor immune responses in tumor microenvironment in a murine triple-negative breast cancer model.

Published in:

Journal of Biomedical Science, 2025, v. 32, n. 1, p. 1, doi. 10.1186/s12929-025-01165-3

By:

Chan, Shih-Hsuan;
Lin, Chin-Yu;
Tseng, Hsuan-Jung;
Wang, Lu-Hai

Publication type:

Article

Precision-cut tumor tissue slices, a novel tool to study the tumor microenvironment interactions with chimeric antigen receptor (CAR) T cells.

Published in:

PLoS ONE, 2025, v. 20, n. 8, p. 1, doi. 10.1371/journal.pone.0327322

By:

Durante, Valeria;
Wittwer, Alina;
Theek, Benjamin;
Martinez-Osuna, Manuel;
Donnadieu, Emmanuel;
Hardt, Olaf;
Eckardt, Dominik;
Bosio, Andreas;
Schallenberg, Sonja;
Herbel, Christoph

Publication type:

Article

Pannexin 1 and pannexin 3 differentially regulate the cancer cell properties of cutaneous squamous cell carcinoma.

Published in:

Journal of Physiology, 2025, v. 603, n. 15, p. 4409, doi. 10.1113/JP286172

By:

O'Donnell, Brooke L.;
Johnston, Danielle;
Bhatt, Ayushi;
Kardan, Zahra;
Stefan, Dan;
Bysice, Andrew;
Sayedyahossein, Samar;
Dagnino, Lina;
Cecchini, Matthew;
Loganathan, Sampath Kumar;
Roth, Kathryn;
Penuela, Silvia

Publication type:

Article

CAFs exosomal circFOXO1 promotes TNBC autophagy and radioresistance via miR-27a-3p/BNIP3 axis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-13876-6

By:

Xun, Xueqiong;
Hu, Huiyong;
Liu, Qing;
Su, Ruijun;
Ai, Jun

Publication type:

Article

Association of HLA-DRA expression with prognosis and tumor microenvironment in clear cell renal cell carcinoma.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-13665-1

By:

Qu, Shu-Xin;
Wang, Xiang;
Han, Wan-Ru;
Ge, Yu-Chen;
Feng, Bei;
Guo, Hai-Ying;
Sun, Xiao-Chen;
Wang, Kai;
Cui, Rui

Publication type:

Article

Prognostic significance of angiogenesis-associated molecules and Immunologic characteristic in elderly patients with acute myeloid leukemia.

Published in:

Annals of Hematology, 2025, v. 104, n. 7, p. 3681, doi. 10.1007/s00277-025-06454-3

By:

Chen, Can;
Huang, Yongfen;
Wang, Lingling;
Zhang, Linlin;
Lu, Jinbo;
Cheng, Yuexin;
Miao, Yuqing

Publication type:

Article

Targeting immune microenvironment in cervical cancer: current research and advances.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06896-3

By:

Zhang, Zhen;
Liu, Miao;
An, Yu;
Gao, Chongqing;
Wang, Tao;
Zhang, Zhi;
Zhang, Guixiang;
Li, Shuo;
Li, Wei;
Li, Mengjia;
Wang, Gangcheng

Publication type:

Article

Probiotic intervention alters immune gene expression and tumor characteristics in experimental breast cancer.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10873-w

By:

Barchelouei, Niloofar Khosrobaki;
Yazdi, Mohammad Hossein;
Haghighat, Setareh

Publication type:

Article

Advances and emerging trends in the tumor microenvironment of colorectal cancer liver metastasis: a bibliometric analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03292-7

By:

Wu, Qiong;
Zhao, Jie;
Sun, Zhongqi;
Jiang, Hao;
Qiao, Guanzhong;
Zhao, Kai;
Fan, Tingting;
Jiang, Huijie

Publication type:

Article

Targeting SPATS2 in lung adenocarcinoma: implications for prognosis and immune-based therapy.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03179-7

By:

Teng, Maorong;
Yan, Fangtao;
Shang, Jingping;
Sun, Xiaohua;
Wang, Yahui;
Shen, Jian

Publication type:

Article

Anti-PD-1 therapy for preventing recurrence and improving survival in hepatocellular carcinoma patients after hepatectomy.

Published in:

BMC Surgery, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12893-025-03117-y

By:

Zhao, Xiansheng;
Peng, Yong;
Hu, Airong;
Jiang, Suwen

Publication type:

Article

Machine learning-driven multi-omics analysis identifies a prognostic gene signature associated with programmed cell death and metabolism in hepatocellular carcinoma.

Published in:

Biological Procedures Online, 2025, v. 27, n. 1, p. 1, doi. 10.1186/s12575-025-00286-1

By:

Li, Xiang;
Yin, Donghao;
Geng, Jiahao;
Xu, Yanyu;
Xu, Zijing;
Yang, Xuemeng;
Li, Quanwei;
Shang, Zimeng;
Yang, Zhiyun;
Xu, Zhong;
Wang, Jiabo;
Zhang, Enxiang;
Song, Xinhua

Publication type:

Article

Spatial deciphering of the transcriptomic heterogeneity of tumor spread through air spaces in lung cancer.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1567527

By:

Wang, Wenhao;
Zhou, Wenhao;
Fan, Jingli;
Jiang, Tao;
Yang, Guang;
Song, Congcong;
Xu, Siwei;
Luo, Haitao;
Liu, Huining

Publication type:

Article

Heterotypic neutrophil-in-tumor structure: A novel pathological feature first discovered in the tissues of OPSCC.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2022.807597

By:

Fan, Jie;
Li, Peng;
Fang, Qigen;
Yang, Yang;
Zhang, He;
Du, Wei;
Liu, Shanting;
Luo, Ruihua

Publication type:

Article

NAP1L5 in acute myeloid leukemia: a prognostic biomarker and potential therapeutic target.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1617564

By:

Wang, Meng;
Xie, Zhibin;
Tan, Yuanyuan;
Zhou, Yan;
Zhang, Tingting;
Du, Yuqing;
Wu, Huan;
Zhou, Lili;
Ge, Jian

Publication type:

Article

Endosialin promotes vascular maturation by inhibiting Cyr61 expression in melanoma metastasis.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1528288

By:

Lu, Tong;
Song, Hongtao;
Zhao, Zhite;
He, Xinglin;
Xu, Chao;
Liu, Shaojie;
Qin, Weijun;
Yang, Bo;
Yang, Lijun

Publication type:

Article

Heterotypic neutrophil-in-tumor structure: A novel pathological feature first discovered in the tissues of OPSCC.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2022.807597

By:

Fan, Jie;
Li, Peng;
Fang, Qigen;
Yang, Yang;
Zhang, He;
Du, Wei;
Liu, Shanting;
Luo, Ruihua

Publication type:

Article

Correction: Myeloid Zinc Finger 1 : insights into its oncogenic potential, prognostic value, and impact on immune microenvironment across cancers.

Published in:

2025

By:

Tian, Wenze;
Yu, Chun;
Xu, Xin;
Li, Jiaqi;
Peng, Shuangfu;
Sun, Aijun;
Zhang, Shasha;
Jiang, Chao

Publication type:

Correction Notice

Harnessing innate immunity against glioblastoma microenvironment.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1648601

By:

Zhang, Wenbo;
Zhang, Wanhong;
Wu, Henghao;
Han, Xinsheng

Publication type:

Article

Correction: Crosstalk between the tumor immune microenvironment and metabolic reprogramming in pancreatic cancer: new frontiers in immunotherapy.

Published in:

2025

By:

Shi, Taijin;
Cui, Xiaoyan;
Wang, Junlin;
Liu, Guangqia;
Meng, Jiayin;
Zhang, Yingjie

Publication type:

Correction Notice

Research progress on mechanisms of tumor immune microenvironment and gastrointestinal resistance to immunotherapy: mini review.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1641518

By:

Zhang, Zheng;
Wu, Yangping

Publication type:

Article

Single-cell transcriptomic profiling reveals the heterogeneity of epithelial cells in lung adenocarcinoma lymph node metastasis and develops a prognostic signature.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1637625

By:

Mu, Qiuqiao;
Zhang, Han;
Shi, Ying;
Xue, Mengli;
Wang, Jingxian;
Ding, Yun;
Tan, Lin;
Yuan, Hui;
Li, Xin;
Sun, Daqiang

Publication type:

Article

Single-cell and spatial atlas of glioblastoma heterogeneity: characterizing the PCLAF + subtype and YEATS4 's oncogenic role.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1614549

By:

Ma, Siqi;
Sun, Yuwei;
Zheng, Shaowei;
Fu, Yilong;
Wang, Liangyu;
Liu, Dun;
Jiao, Henan;
Zhu, Xuqiang;
Li, Xueyuan;
Yan, Dongming;
Chen, Di;
Ye, Zi

Publication type:

Article

Tumor-infiltrating lymphocytes in NSCLC: from immune surveillance to immunotherapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1610998

By:

Xue, Haiyi;
Fan, Yilan;
Li, Yi;
Zhao, Qian;
Zhang, Xuelu;
Zhao, Pei;
Liu, Zhenjun

Publication type:

Article

Crosstalk between the tumor immune microenvironment and metabolic reprogramming in pancreatic cancer: new frontiers in immunotherapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1564603

By:

Shi, Taijin;
Cui, Xiaoyan;
Wang, Junlin;
Liu, Guangqia;
Meng, Jiayin;
Zhang, Yingjie

Publication type:

Article

Anaerobic gut bacteria and their potential role in the initiation, exacerbation, and development of human colorectal cancer: a narrative review.

Published in:

Frontiers in Cellular & Infection Microbiology, 2025, p. 1, doi. 10.3389/fcimb.2025.1559001

By:

Sabour, Sahar;
Sadeghi Koupaei, Hanieh;
Ghasemi, Hadi;
Amin, Mansour;
Azimi, Taher

Publication type:

Article

The role of environmentally mediated drug resistance in facilitating the spatial distribution of residual disease.

Published in:

Communications Biology, 2025, p. 1, doi. 10.1038/s42003-025-08585-9

By:

Milne, Amy;
Marusyk, Andriy;
Maini, Philip K.;
Anderson, Alexander R. A.;
Picco, Noemi

Publication type:

Article

Bioorthogonal Click‐to‐Release of Branched Pro‐Fluorophores.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 42, p. 1, doi. 10.1002/chem.202501544

By:

Brind, Thomasin;
Lawer, Aggie;
Todd, Tobias;
Aryal, Sushant;
Hook, Sarah;
Gamble, Allan B.

Publication type:

Article

Decoding NF-κB: nucleocytoplasmic shuttling dynamics, synthetic modulation and post-therapeutic behavior in cancer.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10917-1

By:

Alhallaq, Ahmed S.;
Sultan, Nadeen S.

Publication type:

Article

Connexin 43 inhibitors reduce cell viability in glioblastoma and astrocyte co-culture systems.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10902-8

By:

Genc, Ali;
Uzunkaya, Berfin;
Yengin, Gizem Inetas;
Tecimel, Didem;
Dalan, Altay Burak;
Bayrak, Omer Faruk

Publication type:

Article

OPPORTUNITIES AND CHALLENGES FOR TARGETING CANCER METABOLISM.

Published in:

Transactions of the American Clinical & Climatological Association, 2025, n. 135, p. 196

By:

DANG, CHI V.

Publication type:

Article

Effective Macroscopic Equations for Biological Fluid and Nutrients' Transport in Vascularized Tumors Growing Via Proliferation and Chemotaxis.

Published in:

Mathematical Methods in the Applied Sciences, 2025, v. 48, n. 14, p. 13285, doi. 10.1002/mma.11102

By:

Ballatore, Francesca;
Giverso, Chiara;
Penta, Raimondo

Publication type:

Article

Multi-omics dissection of CPNE1 reveals its prognostic value and immune-regulatory function in liver cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03366-6

By:

Liu, Liu;
Hong, He;
Zhang, Weiwei;
Li, Xiang;
Yao, Yuan;
Zhang, Zhengjun;
Li, Guangyao

Publication type:

Article

Mapping thirty years of tumour-microenvironment-driven drug resistance in breast cancer: a global bibliometric analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03324-2

By:

Duan, Zuoping;
Zhou, Yonghong;
Wu, Yang

Publication type:

Article

Advanced diffusion-weighted imaging biomarkers for non-invasive assessment of tumor microenvironment in rectal cancer: restricted spectrum imaging.

Published in:

Abdominal Radiology, 2025, v. 50, n. 9, p. 3917, doi. 10.1007/s00261-025-04819-w

By:

Yuan, Jie;
Sun, Yiqun;
Liu, Kun;
Han, Gang;
Wang, Ziyuan;
Liu, Mengxiao;
Dai, Yongming;
Tang, Cui;
Wu, Dongmei

Publication type:

Article

Pan-cancer landscape of ITGAV and its potential role in gastric cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-14342-z

By:

Ke, Bin;
Jin, Peng;
Wang, Xue-Jun;
Zhang, Ru-peng;
Liu, Ning;
Ma, Gang

Publication type:

Article

Machine learning derived development and validation of extracellular matrix related signature for predicting prognosis in adolescents and young adults glioma.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-13547-6

By:

Wu, Pancheng;
Zheng, Yi;
Wu, Wei;
Zhang, Beichen;
Wang, Yichang;
Zhou, Mingjing;
Liu, Ziyi;
Wang, Zhao;
Wang, Maode;
Wang, Jia

Publication type:

Article

Sorafenib-treated Th9 cells exhibit superior anti-tumor effect in lung metastasis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-11450-8

By:

Yuan, Fanli;
Wang, Hanliang;
Wang, Shuowang;
Wang, Jin;
Li, Junwei;
Shen, Yingying;
Lin, Jianjun;
Guo, Jufeng;
Cai, Lingzhi

Publication type:

Article

Identification of SMYD2 as a candidate diagnostic and prognostic biomarker for gastric cancer.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1617971

By:

Wang, Sichao;
Zhao, Chuanxi;
Li, Dongmei;
Liu, Qingzhi;
Mao, Cuiping;
Ding, Shanshan;
Zhang, Shujun;
Shang, Wenjing

Publication type:

Article

Global research landscape of antiangiogenic therapy for colorectal cancer: a bibliometric analysis of mechanistic insights and clinical advancements.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1591059

By:

Hou, Ke-Qiang;
Wu, Jia-Ming;
Chen, Jie

Publication type:

Article

Transglutaminase 2 regulates ovarian cancer metastasis by modulating the immune microenvironment.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1639853

By:

Ibrahim, Dalia;
Grondin, Melanie;
Galpin, Kristianne;
Asif, Sara;
Thompson, Emily;
Nersesian, Sarah;
Abou-Hamad, John;
Echaibi, Maryam;
Rodriguez, Galaxia M.;
Navals, Pauline;
Macdonald, Elizabeth;
Ryan, Brianna;
Cook, David P.;
Keillor, Jeffrey W.;
Vanderhyden, Barbara C.

Publication type:

Article

Immunotherapy enhances the risk of tumor oxidative stress and metastasis in lung cancer with radiation pneumonitis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1629170

By:

Jiao, Ruidi;
Xu, Wenbo;
Xu, Kunpeng;
Zhang, Mingxia;
Liu, Weilong;
Jiang, Wei;
Wang, Luhua

Publication type:

Article

Alveolar macrophages maintain tissue localization and gain enhanced anti-tumor activity in Lewis lung carcinoma-reprogrammed lung microenvironment.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1616514

By:

Ren, Mengfei;
Dou, Jiaxiang;
Yue, Qian;
Ma, Liqin;
Yu, Hang;
Shang, Shengwen;
Wang, Shijie;
Wang, Jian;
Li, Tingting;
Li, Fengqi

Publication type:

Article

Cancer-specific senescence signature promotes malignant phenotypes and immunotherapy resistance in colorectal cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1603787

By:

Wang, Wei;
Ling, Fengyu;
Huang, Dong;
Luo, Guomin;
Duan, Bixia

Publication type:

Article

Pygo2+ T cells possess immunosuppressive features and inferior immunotherapeutic response in gastric cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1596434

By:

Chang, Weilong;
Yan, Huifang;
Zhang, Yawei;
Sang, Zibo;
Bu, Bei;
Deng, Rui;
Li, Kaibo;
Li, Jiajing;
Fu, Yang;
Cui, Jinyuan

Publication type:

Article

Immune analysis according to Lauren type for gastric cancer and its significance in individual treatment and prognostic prediction.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1589513

By:

Lu, Huiwen;
Yao, Junqiao;
Xue, Chi;
Huang, Rui;
Huang, Baojun

Publication type:

Article

Revolutionizing cervical cancer treatment: single-cell sequencing of TSPAN1+ tumor EPCs and immune checkpoints to assess drug sensitivity and optimize therapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1574174

By:

Li, Yumeng;
Lin, Zhiheng;
Lin, Guangyao;
Zhao, Zhijie;
Xiahou, Zhikai;
Cai, Pingping

Publication type:

Article

Identification of a coagulation-related classification and signature that predict disease heterogeneity for colorectal cancer and pan-cancer patients.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1572701

By:

Pei, Junpeng;
Gao, Yuye;
Xing, Baojian;
Chen, Yongjiu;
Wu, Aiwen

Publication type:

Article

Comprehensive review of the resistance mechanisms of colorectal cancer classified by therapy type.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1571731

By:

Oh, Janice M.;
Kim, Susan;
Tsung, Carolyn;
Kent, Eric;
Jain, Arad;
Ruff, Samantha M.;
Zhang, Hongji

Publication type:

Article

Interplay between tumor mutation burden and the tumor microenvironment predicts the prognosis of pan-cancer anti-PD-1/PD-L1 therapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1557461

By:

Liao, Wuyuan;
Zhou, Xinwei;
Lin, Hansen;
Feng, Zihao;
Chen, Xinyan;
Chen, Yuhang;
Chen, Minyu;
Lin, Mingjie;
Yao, Gaosheng;
Chen, Jinwei;
Feng, Haoqian;
Wang, Yinghan;
Tan, Zhiping;
Tan, Youyan;
Lu, Jun;
Li, Pengju;
Wei, Jinhuan;
Luo, Li;
Fu, Liangmin

Publication type:

Article