Comparison of Prophylactic Effect of (Metoclopramide Plus Dexamethasone) And (Ondansetron) in Female Patients Underwent Laparoscopic Gynecological Surgeries.

Mehdi, Enas Ibrahim; Abdulsattar, Abdulrahman E.

Post-operative nausea and vomiting were common complicationsin laparoscopic gynecological surgeries. The study was done to evaluate the effectiveness ofondansetron againstcombination of metoclopramide plus dexamethasone in preventionof postoperative nausea and vomiting (PONV) in laparoscopicgynecological surgeries. Fifty ASAI and II consenting patients aged 20-50 years scheduled for laparoscopic gynecological surgeries wererandomlyallocated into two groups; each group was received either intravenous ondansetron (4 mg) or intravenous metoclopramide (10 mg) plus dexamethasone (8 mg) before inductionof anesthesia. post operativenausea and vomiting then monitoredin period of 4 hours before discharging the patients. Nausea was seen in10 (40%) of patients of ondansetron groups as compared with 16 (64%) in metoclopramide plus dexamethasone. Nausea with blenching developed in 1 (4%) patients of ondansetron group as compared with 8 (32%) patients ofmetoclopramide group. The post operative nausea and vomiting in the ondansetron group was significantly minimum as compared with metoclopramide plus dexamethasone group as p value was 0.01, only 1 (4%) patient of metoclopramide plus dexamethasone group was develops less than 3 times vomiting and non of both groups were develop more than 3 times. Ondansetron was superior to metoclopramide plus dexamethasone in prophylaxis of post operative nausea and vomiting in patients undergoing gynecological laparoscopic surgeries.

GYNECOLOGIC surgery; LAPAROSCOPIC surgery; METOCLOPRAMIDE; WOMEN patients; DEXAMETHASONE; POSTOPERATIVE nausea & vomiting

Indian Journal of Public Health Research & Development, 2019, Vol 10, Issue 11, p4815

0976-0245

Academic Journal

10.5958/0976-5506.2019.03912.3