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- Title
Physiological and Biochemical Effects of Rosemary (Rosemarinus afficinalis) water extract and vitamin E in Males of New Zealand Rabbits with Induced Hyperlipidemia.
- Authors
Hadree, Dakheel Hussein; Awad, Ali Hassan; Dhaher, Nawaf N.
- Abstract
Background:- The aim of the study was to determine the protective effect for the water extract of the leaves of the rosemary plant and vitamin E in reducing the oxidative stress induced by cholesterol and the activation of antioxidants in New Zealand white rabbits. Material and Method: A total of 24 rabbits were distributed randomly to 4 equal groups 1 control, rabbits fed a diet rich in cholesterol (1% g/kg) and 3 treated groups (2nd group fed diet supplemented with rosemary extract 50 g / kg of animal weight, 3rd group fed diet supplemented with 50 mg / kg of Vitamin E, while 4th group fed diet supplemented with a mixture of vit E, for 30 days. Blood samples were taken for laboratory tests. Results: The results showed that in the second, third and fourth groups showed a significant decrease at level( p≤0.01) in the concentration of total cholesterol, triglycerides, high-density lipoproteins, lipoproteins, low density, lipid concentration, and very low density, comparative with cholesterol control group while showed glutathione levels were increased (p≤0.01) with 3 treated groups, while malondialdehyde was obviously decreased compared with the cholesterol control group. Conclusion:- We conclude from the above that the studied transactions have a preventive role against the negative effect of excessive increase in the level of harmful fats on physiological and biochemical variables.
- Publication
Indian Journal of Forensic Medicine & Toxicology, 2019, Vol 13, Issue 4, p585
- ISSN
0973-9122
- Publication type
Academic Journal
- DOI
10.5958/0973-9130.2019.00352.9