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- Title
Gastrointestinal stromal tumor: advances in diagnosis and management.
- Authors
Patil, Deepa T; Rubin, Brian P
- Abstract
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract and should be differentiated from other mesenchymal tumors. They harbor specific activating mutations in the KIT or platelet-derived growth factor receptor α ( PDGFRA ) receptor tyrosine kinases, which makes them responsive to pharmacologic inhibitors, such as imatinib mesylate and sunitinib malate.
- Publication
Archives of pathology & laboratory medicine, 2011, Vol 135, Issue 10, p1298
- ISSN
1543-2165
- Publication type
Journal Article
- DOI
10.5858/arpa.2011-0022-RA