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- Title
Pathogen inactivation: the definitive safeguard for the blood supply.
- Authors
Bryant, Barbara J; Klein, Harvey G
- Abstract
Pathogen inactivation provides a proactive approach to cleansing the blood supply. In the plasma fractionation and manufacturing industry, pathogen inactivation technologies have been successfully implemented resulting in no transmission of human immunodeficiency, hepatitis C, or hepatitis B viruses by US-licensed plasma derivatives since 1985. However, these technologies cannot be used to pathogen inactivate cellular blood components. Although current blood donor screening and disease testing has drastically reduced the incidence of transfusion-transmitted diseases, there still looms the threat to the blood supply of a new or reemerging pathogen. Of particular concern is the silent emergence of a new agent with a prolonged latent period in which asymptomatic infected carriers would donate and spread infection.
- Publication
Archives of pathology & laboratory medicine, 2007, Vol 131, Issue 5, p719
- ISSN
1543-2165
- Publication type
Journal Article
- DOI
10.5858/2007-131-719-PITDSF