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- Title
Recurring translocation (10;17) and deletion (14q) in clear cell sarcoma of the kidney.
- Authors
Brownlee, Noel A; Perkins, L Allen; Stewart, Will; Jackle, Beth; Pettenati, Mark J; Koty, Patrick P; Iskandar, Samy S; Garvin, A Julian
- Abstract
Clear cell sarcoma of the kidney (CCSK) is a prognostically unfavorable renal neoplasm of childhood. Previous cytogenetic studies of CCSK have reported balanced translocations t(10;17)(q22;p13) and t(10;17)(q11;p12). Although the tumor suppressor gene p53 is located at the chromosome 17p13 breakpoint, p53 abnormalities are rarely present in these tumors.
- Publication
Archives of pathology & laboratory medicine, 2007, Vol 131, Issue 3, p446
- ISSN
1543-2165
- Publication type
Journal Article
- DOI
10.5858/2007-131-446-RTADQI