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- Title
Hepatosplenic αβ T-Cell Lymphoma.
- Authors
Jingyu Dong, Amy; Yap-Yee Chong, Howard J.; Meyerson, Howard J.
- Abstract
Hepatosplenic T-cell lymphoma is an uncommon neoplasm characterized by a lymphoid infiltrate within the sinusoids of the liver, spleen, and bone marrow, without significant nodal involvement. The majority of cases express the γδ T-cell receptor and are associated with an isochromosome 7q cytogenetic abnormality. Recently, a small number of cases have been reported that express the ab T-cell receptor. Here, we report our findings of a case of an S100-positive hepatosplenic αβ T-cell lymphoma in a 20-year-old woman who presented with pancytopenia and hepatosplenomegaly. The case adds to the growing litera-ture of hepatosplenic αβ T-cell lymphomas.
- Publication
Archives of Pathology & Laboratory Medicine, 2003, Vol 127, Issue 3, pe119
- ISSN
0003-9985
- Publication type
Academic Journal
- DOI
10.5858/2003-127-e119-htlaro