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- Title
Microsatellite instability in colorectal carcinoma. The comparison of immunohistochemistry and molecular biology suggests a role for hMSH6 [correction of hMLH6] immunostaining.
- Authors
Rigau, Valérie; Sebbagh, Nicole; Olschwang, Sylviane; Paraf, François; Mourra, Najat; Parc, Yann; Flejou, Jean-François
- Abstract
Microsatellite instability (MSI) due to defective mismatch repair (MMR) genes has been reported in the majority of colorectal tumors from patients with hereditary nonpolyposis colorectal cancer syndrome and in 10% to 15% of sporadic colorectal cancers. The identification of cancers associated with MSI requires classical molecular testing as the gold standard.
- Publication
Archives of pathology & laboratory medicine, 2003, Vol 127, Issue 6, p694
- ISSN
1543-2165
- Publication type
Journal Article
- DOI
10.5858/2003-127-694-MIICC