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- Title
Effect of spironolactone on diabetic nephropathy compared to the combination of spironolactone and losartan.
- Authors
Makhlough, Atieh; Kashi, Zahra; Akha, Ozra; Zaboli, Ehsan; Yazdanicharati, Jamshid
- Abstract
Diabetic nephropathy is the most important cause of end stage renal disease (ESRD). Aldosterone is involved in renal damage through induction of fibrosis, inflammation and necrosis in the kidney tissue. Previous studies have demonstrated that the combination of angiotensin receptor blocker (ARB) and spironolactone (an anti-aldosterone drug) are efficient for albuminuria reduction.
- Publication
Nephro-urology monthly, 2014, Vol 6, Issue 1, pe12148
- ISSN
2251-7006
- Publication type
Journal Article
- DOI
10.5812/numonthly.12148