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- Title
Cholinesterases, a target of pharmacology and toxicology.
- Authors
Pohanka, Miroslav
- Abstract
Cholinesterases are a group of serine hydrolases that split the neurotransmitter acetylcholine (ACh) and terminate its action. Of the two types, butyrylcholinesterase and acetylcholinesterase (AChE), AChE plays the key role in ending cholinergic neurotransmission. Cholinesterase inhibitors are substances, either natural or man-made that interfere with the break-down of ACh and prolong its action. Hence their relevance to toxicology and pharmacology.
- Publication
Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2011, Vol 155, Issue 3, p219
- ISSN
1804-7521
- Publication type
Journal Article
- DOI
10.5507/bp.2011.036