We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Aspirin reduces cutaneous flushing after administration of an optimized extended-release niacin formulation.
- Authors
Cefali, E A; Simmons, P D; Stanek, E J; McGovern, M E; Kissling, C J
- Abstract
Niacin is an effective treatment for dyslipidemia due to its favorable effects on multiple lipid parameters. Clinical utility of niacin is sometimes limited, however, because of cutaneous flushing. A once-daily, extended-release (ER) niacin formulation has been shown to significantly reduce flushing compared to immediate-release niacin. An optimized (reformulated) version of niacin ER has recently been developed and was shown in a previous study to significantly reduce flushing intensity (severity) compared to the non-optimized (commercial) formulation. The current study was designed to evaluate the effect of aspirin on various indices of flushing when administered with the optimized niacin ER formulation.
- Publication
International journal of clinical pharmacology and therapeutics, 2007, Vol 45, Issue 2, p78
- ISSN
0946-1965
- Publication type
Journal Article
- DOI
10.5414/cpp45078