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- Title
Pharmacokinetic properties and bioequivalence of olmesartan medoxomil/hydrochlorothiazide in healthy Korean male subjects.
- Authors
Jin, Changyun; Jeon, Ji-Young; Im, Yong-Jin; Jung, Jin-A; Kim, Yunjeong; Park, Kwangkyu; Choi, Yoonho; Chae, Soo-Wan; Kim, Min-Gul
- Abstract
Olmesartan medoxomil inhibits the vasoconstrictor effects of angiotensin II. Hydrochlorothiazide (HCTZ) promotes sodium excretion, resulting in a reduction of plasma volume and peripheral resistance. A combination of these agents is known to have a greater effect for the treatment of hypertension than monotherapy with either one of these components.
- Publication
International journal of clinical pharmacology and therapeutics, 2014, Vol 52, Issue 1, p64
- ISSN
0946-1965
- Publication type
Journal Article
- DOI
10.5414/CP201991