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- Title
Schistosomiasis among young children in Usoma, Kenya.
- Authors
Verani, Jennifer R; Abudho, Bernard; Montgomery, Susan P; Mwinzi, Pauline N M; Shane, Hillary L; Butler, Sara E; Karanja, Diana M S; Secor, W Evan
- Abstract
Although schistosomiasis burden is greatest among school-age children (SAC) (6-15 years of age), infection among preschool-age children (PSAC) (1-5 years), may be underestimated in endemic areas. We conducted a cross-sectional study evaluating Schistosoma mansoni infection among children 1-15 years of age in a highly endemic community in Kenya. Diagnostic tests included stool exam (Kato/Katz technique), serum testing for schistosome-specific antibodies, and urine testing for circulating cathodic antigen (CCA). Overall, 268 SAC and 216 PSAC were enrolled; prevalence increased with age, with 14% of 1 year olds and more than 90% of children > 10 years of age infected. Stool exam was more sensitive among SAC than PSAC, but performance was similar after adjusting for infection intensity (based on CCA). Schistosomiasis poses a threat to PSAC in endemic areas, and stool exam may underestimate the prevalence of infection. Control programs in such areas should consider PSAC in addition to SAC.
- Publication
The American journal of tropical medicine and hygiene, 2011, Vol 84, Issue 5, p787
- ISSN
1476-1645
- Publication type
Journal Article
- DOI
10.4269/ajtmh.2011.10-0685