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- Title
Distribution and phylogenetic comparisons of a novel mosquito flavivirus sequence present in Culex tarsalis Mosquitoes from western Canada with viruses isolated in California and Colorado.
- Authors
Tyler, Shaun; Bolling, Bethany G; Blair, Carol D; Brault, Aaron C; Pabbaraju, Kanti; Armijos, M Veronica; Clark, David C; Calisher, Charles H; Drebot, Michael A
- Abstract
In a previous study, a new flavivirus genome sequence was identified in Culex tarsalis mosquitoes obtained in Alberta, Canada and was shown to be genetically related to but distinct from members of the insect-specific flaviviruses. Nonstructural protein 5-encoding sequences amplified from Cx. tarsalis pools from western Canada have shown a high similarity to genome sequences of novel flaviviruses isolated from mosquitoes in California and Colorado. Despite wide distribution of this virus, designated Calbertado virus, strains demonstrate a high degree of nonstructural protein 5 nucleotide (> 90%) and amino acid (> 97%) identity. The ecology and geographic range of Calbertado virus warrants further study because it may potentially influence transmission of mosquito-borne flaviviruses, including important human pathogens such as West Nile and Saint Louis encephalitis viruses.
- Publication
The American journal of tropical medicine and hygiene, 2011, Vol 85, Issue 1, p162
- ISSN
1476-1645
- Publication type
Journal Article
- DOI
10.4269/ajtmh.2011.10-0469