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- Title
Inflammasome gene expression alterations in Staphylococcus aureus biofilm-associated chronic rhinosinusitis.
- Authors
Jardeleza, C; Miljkovic, D; Baker, L; Boase, S; Tan, N C W; Koblar, S A; Zalewski, P; Rischmueller, M; Lester, S; Drilling, A; Jones, D; Tan, L W; Wormald, P J; Vreugde, S
- Abstract
The role of inflammasomes in chronic inflammation has been the subject of intense research in recent years. Chronic rhinosinusitis (CRS), a persistent inflammatory disease, continues to be investigated hoping that a clearer pathophysiologic description will guide discovery of future treatment modalities. This study investigates the role of inflammasome complexes in CRS patients with Staphylococcus aureus biofilm infection, a key culprit associated with disease severity and recalcitrance.
- Publication
Rhinology, 2013, Vol 51, Issue 4, p315
- ISSN
0300-0729
- Publication type
Journal Article
- DOI
10.4193/Rhino13.045