We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Endothelin receptor-A is required for the recruitment of antitumor T cells and modulates chemotherapy induction of cancer stem cells.
- Authors
Coffman, Lan; Mooney, Collin; Lim, Jaeyoung; Bai, Shoumei; Silva, Ines; Gong, Yusong; Yang, Kun; Buckanovich, Ronald J
- Abstract
The endothelin receptor-A (ETRA) plays an important role in tumor cell migration, metastasis, and proliferation. The endothelin receptor B (ETRB) plays a critical role in angiogenesis and the inhibition of anti-tumor immune cell recruitment. Thus dual blockade of ETRA and ETRB could have significant anti-tumor effects.
- Publication
Cancer biology & therapy, 2013, Vol 14, Issue 2, p184
- ISSN
1555-8576
- Publication type
Journal Article
- DOI
10.4161/cbt.22959