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- Title
Novel applications of deep brain stimulation.
- Authors
Sankar, Tejas; Tierney, Travis S; Hamani, Clement
- Abstract
The success of deep brain stimulation (DBS) surgery in treating medically refractory symptoms of some movement disorders has inspired further investigation into a wide variety of other treatment-resistant conditions. These range from disorders of gait, mood, and memory to problems as diverse as obesity, consciousness, and addiction. We review the emerging indications, rationale, and outcomes for some of the most promising new applications of DBS in the treatment of postural instability associated with Parkinson's disease, depression, obsessive-compulsive disorder, obesity, substance abuse, epilepsy, Alzheimer's-type dementia, and traumatic brain injury. These studies reveal some of the excitement in a field at the edge of a rapidly expanding frontier. Much work still remains to be done on basic mechanism of DBS, optimal target and patient selection, and long-term durability of this technology in treating new indications.
- Publication
Surgical neurology international, 2012, Vol 3, Issue Suppl 1, pS26
- ISSN
2152-7806
- Publication type
Journal Article
- DOI
10.4103/2152-7806.91607