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- Title
Dosimetric considerations in radioimmunotherapy and systemic radionuclide therapies: a review.
- Authors
Loke, Kelvin S H; Padhy, Ajit K; Ng, David C E; Goh, Anthony S W; Divgi, Chaitanya
- Abstract
Radiopharmaceutical therapy, once touted as the "magic bullet" in radiation oncology, is increasingly being used in the treatment of a variety of malignancies; albeit in later disease stages. With ever-increasing public and medical awareness of radiation effects, radiation dosimetry is becoming more important. Dosimetry allows administration of the maximum tolerated radiation dose to the tumor/organ to be treated but limiting radiation to critical organs. Traditional tumor dosimetry involved acquiring pretherapy planar scans and plasma estimates with a diagnostic dose of intended radiopharmaceuticals. New advancements in single photon emission computed tomography and positron emission tomography systems allow semi-quantitative measurements of radiation dosimetry thus allowing treatments tailored to each individual patient.
- Publication
World journal of nuclear medicine, 2011, Vol 10, Issue 2, p122
- ISSN
1607-3312
- Publication type
Journal Article
- DOI
10.4103/1450-1147.89780