We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Recurrent strokes under anticoagulation therapy: Sticky platelet syndrome combined with a patent foramen ovale.
- Authors
Gehoff, A; Kluge, J G; Gehoff, P; Jurisch, D; Pfeifer, D; Hinz, J; Popov, A F
- Abstract
The sticky platelet syndrome (SPS) is a congenital disorder characterized by platelet hyperaggregability to epinephrine and/or adenosine diphosphate; this predisposes affected individuals to acute myocardial infarction, ischemic optic neuropathy, recurrent venous thromboembolism, and transient ischemic cerebral attacks and strokes. Here, we describe an unusual case with recurrent cerebrovascular accidents due to SPS, in the presence of a patent foramen ovale (PFO). We report an unusual case of a 56-year-old female patient with a PFO, who suffered from recurrent strokes despite long-term medication with clopidogrel for SPS. The patient underwent successful transcatheter closure of the PFO, and, in addition, she has been placed on low-dose acetylsalicylic acid. After 18-month follow-up, she demonstrated an intact atrial septum without any vegetations on the percutaneous device until today. She has had no further thromboembolic events.
- Publication
Journal of cardiovascular disease research, 2011, Vol 2, Issue 1, p68
- ISSN
0976-2833
- Publication type
Case Study
- DOI
10.4103/0975-3583.78600