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- Title
Distinctive microRNA signature of medulloblastomas associated with the WNT signaling pathway.
- Authors
Gokhale, Amit; Kunder, Ratika; Goel, Atul; Sarin, Rajiv; Moiyadi, Aliasgar; Shenoy, Asha; Mamidipally, Chandrasekhar; Noronha, Santosh; Kannan, Sadhana; Shirsat, Neelam Vishwanath
- Abstract
Medulloblastoma is a malignant brain tumor that occurs predominantly in children. Current risk stratification based on clinical parameters is inadequate for accurate prognostication. MicroRNA expression is known to be deregulated in various cancers and has been found to be useful in predicting tumor behavior. In order to get a better understanding of medulloblastoma biology, miRNA profiling of medulloblastomas was carried out in parallel with expression profiling of protein-coding genes.
- Publication
Journal of cancer research and therapeutics, 2010, Vol 6, Issue 4, p521
- ISSN
1998-4138
- Publication type
Journal Article
- DOI
10.4103/0973-1482.77072