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- Title
Cyclophosphamide in pulmonary alveolar hemorrhage due to leptospirosis.
- Authors
Trivedi, Samir V; Vasava, Ashwin H; Patel, Tinkal C; Bhatia, Lovleen C
- Abstract
Severe pulmonary involvement in leptospirosis carries high mortality rates. It is the most common cause of death due to leptospirosis in many parts of India and the world. Exacerbated immune response of the host plays an important role in its pathogenesis. Hence, immunosuppressive drugs could be useful in its treatment. Glucocorticosteroids have been found to be useful in several studies. Cyclophosphamide, an immunosuppressive agent, has been found to be useful in a majority of pulmonary alveolar hemorrhages due to non leptospiral causes. This study was carried out to study the effects of cyclophosphamide in patients with leptospiral pulmonary alveolar hemorrhage.
- Publication
Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2009, Vol 13, Issue 2, p79
- ISSN
1998-359X
- Publication type
Journal Article
- DOI
10.4103/0972-5229.56053