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- Title
Polymorphisms in base-excision & nucleotide-excision repair genes & prostate cancer risk in north Indian population.
- Authors
Mandal, Raju K; Gangwar, Ruchika; Kapoor, Rakesh; Mittal, Rama Devi
- Abstract
Genetic variation in the DNA repair genes might be associated with altered DNA repair capacities (DRC). Reduced DRC due to inherited polymorphisms may increase the susceptibility to cancers. Base excision and nucleotide excision are the two major repair pathways. We investigated the association between two base excision repair (BER) genes (APE1 exon 5, OGG1 exon 7) and two nucleotide excision repair (NER) genes (XPC PAT, XPC exon 15) with risk of prostate cancer (PCa).
- Publication
The Indian journal of medical research, 2012, Vol 135, p64
- ISSN
0971-5916
- Publication type
Journal Article
- DOI
10.4103/0971-5916.93426