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- Title
Association of HLA-B*1502 allele and carbamazepine-induced Stevens-Johnson syndrome among Indians.
- Authors
Mehta, Timir Y; Prajapati, Laxman M; Mittal, Bharti; Joshi, Chaitanya G; Sheth, Jayesh J; Patel, Dinesh B; Dave, Dinkar M; Goyal, Ramesh K
- Abstract
Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis are severe cutaneous reactions caused by certain drugs, including antiepileptic carbamazepine. A strong association has been reported between human leucocyte antigen (HLA)-B*1502 and carbamazepine-induced SJS in Han Chinese patients. European studies suggested that HLA-B*1502 is not a universal marker but is ethnicity-specific for Asians.
- Publication
Indian journal of dermatology, venereology and leprology, 2009, Vol 75, Issue 6, p579
- ISSN
0973-3922
- Publication type
Journal Article
- DOI
10.4103/0378-6323.57718