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- Title
Preliminary investigation of environmental prevalence of Clostridium difficile affecting inpatients in a north Indian hospital.
- Authors
Vaishnavi, C; Singh, M
- Abstract
A preliminary study was conducted to see the prevalence of Clostridium difficile in patients and their environment in a tertiary care hospital. Seventy-nine fecal specimens from hospitalized patients, 176 swab samples from beds and 48 from hands of hospital personnel were investigated. Sixty-three patients received antibiotics and 14 proton pump inhibitors. Abdominal pain was observed in 16 patients with fever in 15 of them. C. difficile culture was positive in 12.6% patients at initial sampling but none were toxin-positive. Eight patients developed diarrhea and five were both culture and toxin-positive. Fifty-one percent of bed swab samples and 62.5% of hand swab samples were culture positive. Similarly 8.5% of bed swab samples and 4.2% of hand swab samples were positive for toxins A and B. The environmental cross-infection between patients and carriage by hospital personnel are plausible sources of C. difficile infection and spread in our hospital.
- Publication
Indian journal of medical microbiology, 2012, Vol 30, Issue 1, p89
- ISSN
1998-3646
- Publication type
Journal Article
- DOI
10.4103/0255-0857.93052