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- Title
Effect of lithium chloride and antineoplastic drugs on survival and cell cycle of androgen-dependent prostate cancer LNCap cells.
- Authors
Azimian-Zavareh, Vajihe; Hossein, Ghamartaj; Janzamin, Ehsan
- Abstract
Glycogen synthase kinase-3β (GSK-3β) has been reported to be required for androgen receptor (AR) activity. This study sought to determine the usefulness of lithium chloride (LiCl) as a highly selective inhibitor of GSK-3β to increase the sensitivity of LNCap cells to doxorubicin (Dox), etoposide (Eto), and vinblastine (Vin) drugs.
- Publication
Indian journal of pharmacology, 2012, Vol 44, Issue 6, p714
- ISSN
1998-3751
- Publication type
Journal Article
- DOI
10.4103/0253-7613.103265