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- Title
High Performance Liquid Chromatographic Determination of Aspirin and Clopidogrel in Tablets.
- Authors
Gandhimathi, M.; Ravi, T. K.
- Abstract
A reverse phase high performance liquid chromatographic method to determine aspirin and clopidogrel in combined dosage form is proposed. The chromatographic resolution of aspirin and clopidogrel was obtained in a mobile phase consisting of 0.1% v/v triethylamine (pH 4.0):acetonitrile in the ratio 25:75% (v/v) in an isocratic elution. A detection wavelength of 225 nm and flow rate of 1 ml/min was used in the study. Nimesulide (20 µg/ml) was used as an internal standard. The system suitability procedures as precision, accuracy, LOD, LOQ, number of theoretical plates and tailing factor were studied.
- Publication
Indian Journal of Pharmaceutical Sciences, 2007, Vol 69, Issue 1, p123
- ISSN
0250-474X
- Publication type
Academic Journal
- DOI
10.4103/0250-474X.32125