We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Spectrophotometric Determination of Fexofenadine Hydrochloride.
- Authors
Kumar, K. Suresh; Ravichandran, V.; Raja, M. K. Mohan Maruga; Thyagu, R.; Dharamsi, A.
- Abstract
A simple and sensitive spectrophotometric method has been developed for the determination of fexofenadine hydrochloride in bulk and pharmaceutical dosage forms. The method is based on the chloroform-extractable pale yellow colour complex formed by the reaction of fexofenadine with bromothymol blue at pH 2.6. The chromogen can be estimated at 412 nm against a reagent blank. This method obeys Beer's law in the concentration range of 10-50 µg/ml of the drug. The optimum reaction conditions and other analytical parameters were also evaluated. The proposed method has been successfully applied to the analysis of bulk drugs and their dosage forms.
- Publication
Indian Journal of Pharmaceutical Sciences, 2006, Vol 68, Issue 6, p841
- ISSN
0250-474X
- Publication type
Academic Journal
- DOI
10.4103/0250-474X.31034