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- Title
Early predisposition to osteomalacia in Indian adults on phenytoin or valproate monotherapy and effective prophylaxis by simultaneous supplementation with calcium and 25-hydroxy vitamin D at recommended daily allowance dosage: a prospective study.
- Authors
Krishnamoorthy, Geetha; Nair, Rahul; Sundar, Uma; Kini, Prayag; Shrivastava, Makardhwaj
- Abstract
Long-term therapy with antiepileptic drugs (AED) may be associated with increased total serum alkaline phosphatase (ALP) levels and reduced serum calcium, inorganic phosphorous, and vitamin D levels. These adverse biochemical alterations have an adverse effect on bone health.
- Publication
Neurology India, 2010, Vol 58, Issue 2, p213
- ISSN
0028-3886
- Publication type
Journal Article
- DOI
10.4103/0028-3886.63796