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- Title
Case of relapsed AIDS-related plasmablastic lymphoma treated with autologous stem cell transplantation and highly active antiretroviral therapy.
- Authors
Goto, Hiroki; Hagiwara, Shotaro; Hirai, Risen; Miyama, Takahiko; Honda, Haruhito; Tagashira, Amane; Iizuka, Toshihiko; Mochizuki, Makoto; Teruya, Katsuji; Kikuchi, Yoshimi; Oka, Shinichi; Miwa, Akiyoshi
- Abstract
Plasmablastic lymphoma is a rare and aggressive malignancy strongly associated with HIV infection. The refractory/relapsed disease rate is high, and the survival rate is characteristically poor. There are no satisfactory salvage regimens for relapsed cases. We successfully performed autologous stem cell transplantation using a regimen consisting of MCNU (ranimustine), etoposide, cytarabine, and melphalan in a Japanese patient with relapsed AIDS-related plasmablastic lymphoma of the oral cavity. Highly active antiretroviral therapy continued during the therapy. Therapy-related toxicity was tolerable, and a total of 40 Gy of irradiation was administered after autologous stem cell transplantation. The patient has remained in complete remission for 16 months since transplantation.
- Publication
Rare tumors, 2011, Vol 3, Issue 1, pe11
- ISSN
2036-3613
- Publication type
Case Study
- DOI
10.4081/rt.2011.e11