We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Endobronchial perineurioma: an unusual soft tissue lesion in an unreported location.
- Authors
Duncan, Lisa; Tharp, Daryl R; Branca, Paul; Lyons, Jim
- Abstract
We report the first case of an endobronchial perineurioma, a rare benign neoplasm typically occurring in soft tissue. A 53-year-old nonsmoking female presented with a three-month history of persistent bronchitis. A CT scan followed by bronchoscopy demonstrated an endobronchial lesion involving the left mainstem bronchus. Removal of the lesion by bronchoscopy was accomplished. The tumor was composed of bland spindle cells in a variably collagenized stroma. These cells had long cytoplasmic processes. No mitotic activity or necrosis was observed. Neoplastic cells were immunoreactive for epithelial membrane antigen (EMA), CD34, and claudin-1. Smooth muscle actin (SMA), desmin, and S-100 immunostains were all negative. Based on the morphologic appearance and immunophenotype, a diagnosis of perineurioma was rendered.
- Publication
Pathology research international, 2010, Vol 2010, p613824
- ISSN
2042-003X
- Publication type
Case Study
- DOI
10.4061/2010/613824