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- Title
Isothiocyanate exposure, glutathione S-transferase polymorphisms, and colorectal cancer risk.
- Authors
Yang, Gong; Gao, Yu-Tang; Shu, Xiao-Ou; Cai, Qiuyin; Li, Guo-Liang; Li, Hong-Lan; Ji, Bu-Tian; Rothman, Nathaniel; Dyba, Marcin; Xiang, Yong-Bing; Chung, Fung-Lung; Chow, Wong-Ho; Zheng, Wei
- Abstract
Isothiocyanates, compounds found primarily in cruciferous vegetables, have been shown in laboratory studies to possess anticarcinogenic activity. Glutathione S-transferases (GSTs) are involved in the metabolism and elimination of isothiocyanates; thus, genetic variations in these enzymes may affect in vivo bioavailability and the activity of isothiocyanates.
- Publication
The American journal of clinical nutrition, 2010, Vol 91, Issue 3, p704
- ISSN
1938-3207
- Publication type
Journal Article
- DOI
10.3945/ajcn.2009.28683