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Title
Moringa oleifera leaf extracts inhibit 6beta-hydroxylation of testosterone by CYP3A4.
Authors
Monera, Tsitsi G; Wolfe, Alan R; Maponga, Charles C; Benet, Leslie Z; Guglielmo, Joseph
Abstract
Moringa oleifera is a tropical tree often used as a herbal medicine, including by people who test positive for HIV. Since herbal constituents may interact with drugs via inhibition of metabolizing enzymes, we investigated the effects of extracts of M. oleifera on the CYP3A4-mediated 6beta-hydroxylation of testosterone.
Publication
Journal of infection in developing countries, 2008, Vol 2, Issue 5, p379