A Case of Multiple Osteoporotic Compression Fractures in Young Man with Budd-Chiari Syndrome.

Sun Hwa Kim; Tae Un Yang; Byeong Kwang Choi; Hye Jin Yoo; Ji A Seo; Kyung Mook Choi; Nan Hee Kim; Sin Gon Kim; Sei Hyun Baik; Dong Seop Choi; Hae Yoon Choi

Osteoporosis in young men is extremely rare. In this report, we demonstrate a rare case of multiple vertebral fractures discovered in a young man with Budd-Chiari syndrome without prior history of trauma. A 29-year-old man was diagnosed as Budd-Chiari syndrome 12 years ago and underwent a mesocaval shunt to relieve the hepatic vein obstruction and was on warfarin therapy. He suffered from low back pain and it was not relieved by analgesics. A T-L spine X-ray revealed multiple compression fractures and the z-score at lumbar spine was -3.7 which is below the expected range for that age. The patient was treated with calcium, vitamin D and bisphosphonate, and showed clinical improvement. This case highlights the importance of the investigation for secondary osteoporosis in young adults with an underlying disease that alters bone metabolism.

OSTEOPOROSIS; BONE diseases; WARFARIN; ANTICOAGULANTS; VITAMIN D deficiency; TREATMENT of fractures

Endocrinology & Metabolism, 2012, Vol 27, Issue 4, p334

2093-596X

Academic Journal

10.3803/enm.2012.27.4.334