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- Title
Effect of perioperative blood transfusion on clinical outcomes in hepatic surgery for cancer.
- Authors
Dionigi, Gianlorenzo; Boni, Luigi; Rovera, Francesca; Rausei, Stefano; Cuffari, Salvatore; Cantone, Giovanni; Bacuzzi, Alessandro; Dionigi, Renzo
- Abstract
Allogeneic blood transfusion during liver resection for malignancies has been associated with an increased incidence of different types of complications: infectious complications, tumor recurrence, decreased survival. Even if there is clear evidence of transfusion-induced immunosuppression, it is difficult to demonstrate that transfusion is the only determinant factor that decisively affects the outcome. In any case there are several motivations to reduce the practice of blood transfusion. The advantages and drawbacks of different transfusion alternatives are reviewed here, emphasizing that surgeons and anesthetists who practice in centers with a high volume of liver resections, should be familiar with all the possible alternatives.
- Publication
World journal of gastroenterology, 2009, Vol 15, Issue 32, p3976
- ISSN
2219-2840
- Publication type
Commentary
- DOI
10.3748/wjg.15.3976