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- Title
Ultrafiltration characteristics of glucose polymers with low polydispersity.
- Authors
Leypoldt, John K; Hoff, Catherine M; Piscopo, Dean; Carr, Seraya N; Svatek, Jessica M; Holmes, Clifford J
- Abstract
Icodextrin, a glucose polymer with a polydispersity [ratio of weight-average molecular weight (Mw) to number-average molecular weight] of approximately 2.6, has been shown, compared with glucose, to provide superior ultrafiltration (UF) efficiency [ratio of UF to carbohydrate (CHO) absorbed] when used as an osmotic agent during a long-dwell peritoneal dialysis exchange. In an experimental rabbit model, we evaluated the effect of Mw on the UF and UF efficiency of glucose polymers with low polydispersity.
- Publication
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 2013, Vol 33, Issue 2, p124
- ISSN
1718-4304
- Publication type
Journal Article
- DOI
10.3747/pdi.2012.00009