Works matching AU Thompson, Paul R.

Results: 71

Chemical and biological methods to detect post-translational modifications of arginine.

Published in:

Biopolymers, 2014, v. 101, n. 2, p. 133, doi. 10.1002/bip.22256

By:

Slade, Daniel J.;
Subramanian, Venkataraman;
Fuhrmann, Jakob;
Thompson, Paul R.

Publication type:

Article

The protein arginine deiminases: Structure, function, inhibition, and disease.

Published in:

Biopolymers, 2013, v. 99, n. 2, p. 155, doi. 10.1002/bip.22127

By:

Bicker, Kevin L.;
Thompson, Paul R.

Publication type:

Article

Pathogen infection and cholesterol deficiency activate the C. elegans p38 immune pathway through a TIR-1/SARM1 phase transition.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.74206

By:

Peterson, Nicholas D.;
Icso, Janneke D.;
Salisbury, Elizabeth J.;
Rodríguez, Tomás;
Thompson, Paul R.;
Pukkila-Worley, Read

Publication type:

Article

Synthesis and Anticancer Activity of Structure Simplified Naturally Inspired Dimeric Chromenone Derivatives.

Published in:

European Journal of Organic Chemistry, 2019, v. 2019, n. 41, p. 6917, doi. 10.1002/ejoc.201901026

By:

Ali, Rameez;
Guan, Yong;
Leveille, Alexandria N.;
Vaughn, Elizabeth;
Parelkar, Sangram;
Thompson, Paul R.;
Mattson, Anita E.

Publication type:

Article

Cover Feature: Synthesis and Anticancer Activity of Structure Simplified Naturally Inspired Dimeric Chromenone Derivatives (Eur. J. Org. Chem. 41/2019).

Published in:

European Journal of Organic Chemistry, 2019, v. 2019, n. 41, p. 6889, doi. 10.1002/ejoc.201901544

By:

Ali, Rameez;
Guan, Yong;
Leveille, Alexandria N.;
Vaughn, Elizabeth;
Parelkar, Sangram;
Thompson, Paul R.;
Mattson, Anita E.

Publication type:

Article

Citrullination profile analysis reveals peptidylarginine deaminase 3 as an HSV-1 target to dampen the activity of candidate antiviral restriction factors.

Published in:

PLoS Pathogens, 2023, v. 19, n. 12, p. 1, doi. 10.1371/journal.ppat.1011849

By:

Pasquero, Selina;
Gugliesi, Francesca;
Biolatti, Matteo;
Dell'Oste, Valentina;
Albano, Camilla;
Bajetto, Greta;
Griffante, Gloria;
Trifirò, Linda;
Brugo, Bianca;
Raviola, Stefano;
Lacarbonara, Davide;
Yang, Qiao;
Sudeshna, Sen;
Barasa, Leonard;
Haniff, Hafeez;
Thompson, Paul R.;
Landolfo, Santo;
De Andrea, Marco

Publication type:

Article

Peptidylarginine deiminase 1-catalyzed histone citrullination is essential for early embryo development.

Published in:

Scientific Reports, 2016, p. 38727, doi. 10.1038/srep38727

By:

Zhang, Xiaoqian;
Liu, Xiaoqiu;
Zhang, Mei;
Li, Tingting;
Muth, Aaron;
Thompson, Paul R.;
Coonrod, Scott A.;
Zhang, Xuesen

Publication type:

Article

Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses.

Published in:

Scientific Reports, 2016, p. 26430, doi. 10.1038/srep26430

By:

Kawalkowska, Joanna;
Quirke, Anne-Marie;
Ghari, Fatemeh;
Davis, Simon;
Subramanian, Venkataraman;
Thompson, Paul R.;
Williams, Richard O.;
Fischer, Roman;
La Thangue, Nicholas B.;
Venables, Patrick J.

Publication type:

Article

Applicability of Small-Molecule Inhibitors in the Study of Peptidyl Arginine Deiminase 2 (PAD2) and PAD4.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.716250

By:

Martín Monreal, María Teresa;
Rebak, Alexandra Stripp;
Massarenti, Laura;
Mondal, Santanu;
Šenolt, Ladislav;
Ødum, Niels;
Nielsen, Michael L.;
Thompson, Paul R.;
Nielsen, Claus H.;
Damgaard, Dres

Publication type:

Article

Muscle‐specific pyruvate kinase isoforms, PKM1 and PKM2, regulate mammalian SWI/SNF proteins and histone 3 phosphorylation during myoblast differentiation.

Published in:

FASEB Journal, 2024, v. 38, n. 11, p. 1, doi. 10.1096/fj.202400784R

By:

Olea‐Flores, Monserrat;
Sharma, Tapan;
Verdejo‐Torres, Odette;
DiBartolomeo, Imaru;
Thompson, Paul R.;
Padilla‐Benavides, Teresita;
Imbalzano, Anthony N.

Publication type:

Article

Deimination of linker histones links neutrophil extracellular trap release with autoantibodies in systemic autoimmunity.

Published in:

FASEB Journal, 2014, v. 28, n. 7, p. 2840, doi. 10.1096/fj.13-247254

By:

Dwivedi, Nishant;
Neeli, Indira;
Schall, Nicolas;
Haibao Wan;
Desiderio, Dominic M.;
Csernok, Elena;
Thompson, Paul R.;
Dali, Hayet;
Briand, Jean-Paul;
Muller, Sylviane;
Radic, Marko

Publication type:

Article

Kinetic characterization and substrate specificity studies of Protein Arginine Deiminase 4 (PAD4).

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A642, doi. 10.1096/fasebj.21.5.a642

By:

Bhatia, Monica;
Thompson, Paul R.

Publication type:

Article

Histone Citrullination Represses MicroRNA Expression, Resulting in Increased Oncogene mRNAs in Somatolactotrope Cells.

Published in:

Molecular & Cellular Biology, 2018, v. 38, n. 19, p. 1, doi. 10.1128/MCB.00084-18

By:

DeVore, Stanley B.;
Young, Coleman H.;
Guangyuan Li;
Sundararajan, Anitha;
Ramaraj, Thiruvarangan;
Mudge, Joann;
Schilkey, Faye;
Muth, Aaron;
Thompson, Paul R.;
Cherrington, Brian D.

Publication type:

Article

Neutrophil extracellular traps exacerbate Th1-mediated autoimmune responses in rheumatoid arthritis by promoting DC maturation.

Published in:

European Journal of Immunology, 2016, v. 46, n. 11, p. 2542, doi. 10.1002/eji.201646542

By:

Papadaki, Garyfalia;
Kambas, Konstantinos;
Choulaki, Christiana;
Vlachou, Katerina;
Drakos, Elias;
Bertsias, George;
Ritis, Konstantinos;
Boumpas, Dimitrios T.;
Thompson, Paul R.;
Verginis, Panayotis;
Sidiropoulos, Prodromos

Publication type:

Article

Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

Published in:

BMC Cancer, 2012, v. 12, n. 1, p. 1, doi. 10.1186/1471-2407-12-500

By:

McElwee, John L.;
Mohanan, Sunish;
Griffith, Obi L.;
Breuer, Heike C.;
Anguish, Lynne J.;
Cherrington, Brian D.;
Palmer, Ashley M.;
Howe, Louise R.;
Subramanian, Venkataraman;
Causey, Corey P.;
Thompson, Paul R.;
Gray, Joe W.;
Coonrod, Scott A.

Publication type:

Article

Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.

Published in:

2012

By:

McElwee, John L;
Mohanan, Sunish;
Griffith, Obi L;
Breuer, Heike C;
Anguish, Lynne J;
Cherrington, Brian D;
Palmer, Ashley M;
Howe, Louise R;
Subramanian, Venkataraman;
Causey, Corey P;
Thompson, Paul R;
Gray, Joe W;
Coonrod, Scott A

Publication type:

journal article

Laboratories for change: Lessons from 15 years of demonstration projects.

Published in:

Public Personnel Management, 1993, v. 22, n. 4, p. 675, doi. 10.1177/009102609302200413

By:

Thompson, Paul R.

Publication type:

Article

The structural basis of protein acetylation by the p300/CBP transcriptional coactivator.

Published in:

Nature, 2008, v. 451, n. 7180, p. 846, doi. 10.1038/nature06546

By:

Xin Liu;
Ling Wang;
Zhao, Kehao;
Thompson, Paul R.;
Hwang, Yousang;
Marmorstein, Ronen;
Cole, Philip A.

Publication type:

Article

A novel role for peptidylarginine deiminases in microvesicle release reveals therapeutic potential of PAD inhibition in sensitizing prostate cancer cells to chemotherapy.

Published in:

Journal of Extracellular Vesicles, 2015, v. 4, p. 1, doi. 10.3402/jev.v4.26192

By:

Kholia, Sharad;
Jorfi, Samireh;
Thompson, Paul R.;
Causey, Corey P.;
Nicholas, Anthony P.;
Inal, Jameel M.;
Lange, Sigrun

Publication type:

Article

A novel role for protein arginine deiminase 4 in pluripotency: The emerging role of citrullinated histone H1 in cellular programming.

Published in:

BioEssays, 2014, v. 36, n. 8, p. 736, doi. 10.1002/bies.201400057

By:

Slade, Daniel J.;
Horibata, Sachi;
Coonrod, Scott A.;
Thompson, Paul R.

Publication type:

Article

Crystal Structure of SARS-CoV-2 Main Protease in Complex with the Non-Covalent Inhibitor ML188.

Published in:

Viruses (1999-4915), 2021, v. 13, n. 2, p. 174, doi. 10.3390/v13020174

By:

Lockbaum, Gordon J.;
Reyes, Archie C.;
Lee, Jeong Min;
Tilvawala, Ronak;
Nalivaika, Ellen A.;
Ali, Akbar;
Kurt Yilmaz, Nese;
Thompson, Paul R.;
Schiffer, Celia A.;
Rein, Alan

Publication type:

Article

Halogen Bonding Increases the Potency and Isozyme Selectivity of Protein Arginine Deiminase 1 Inhibitors.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 36, p. 12476, doi. 10.1002/anie.201906334

By:

Mondal, Santanu;
Gong, Xuefeng;
Zhang, Xiaoqian;
Salinger, Ari J.;
Zheng, Li;
Sen, Sudeshna;
Weerapana, Eranthie;
Zhang, Xuesen;
Thompson, Paul R.

Publication type:

Article

Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice.

Published in:

2021

By:

Sodré, Fernanda M.C.;
Bissenova, Samal;
Bruggeman, Ylke;
Tilvawala, Ronak;
Cook, Dana P.;
Berthault, Claire;
Mondal, Santanu;
Callebaut, Aïsha;
You, Sylvaine;
Scharfmann, Raphael;
Mallone, Roberto;
Thompson, Paul R.;
Mathieu, Chantal;
Buitinga, Mijke;
Overbergh, Lut

Publication type:

journal article

Peptidylarginine deiminases: novel drug targets for prevention of neuronal damage following hypoxic ischemic insult (HI) in neonates.

Published in:

Journal of Neurochemistry, 2014, v. 130, n. 4, p. 555, doi. 10.1111/jnc.12744

By:

Lange, Sigrun;
Rocha‐Ferreira, Eridan;
Thei, Laura;
Mawjee, Priyanka;
Bennett, Kate;
Thompson, Paul R.;
Subramanian, Venkataraman;
Nicholas, Anthony P.;
Peebles, Donald;
Hristova, Mariya;
Raivich, Gennadij

Publication type:

Article

Methyllysine analogs: rewriting the code.

Published in:

Nature Chemical Biology, 2007, v. 3, n. 5, p. 249, doi. 10.1038/nchembio0507-249

By:

Bhatia, Monica;
Thompson, Paul R

Publication type:

Article

AFM41a: A Novel PAD2 Inhibitor for Sepsis Treatment—Efficacy and Mechanism.

Published in:

International Journal of Biological Sciences, 2024, v. 20, n. 13, p. 5043, doi. 10.7150/ijbs.97166

By:

Tao Dong;
Barasa, Leonard;
Xin Yu;
Wenlu Ouyang;
Liujiazi Shao;
Chao Quan;
Su He Wang;
Jifeng Zhang;
Salmon, Morgan;
Tsung, Allan;
Alam, Hasan B.;
Jianjie Ma;
Thompson, Paul R.;
Yongqing Li

Publication type:

Article

BB-Cl-Amidine as a novel therapeutic for canine and feline mammary cancer via activation of the endoplasmic reticulum stress pathway.

Published in:

2018

By:

Ledet, Melissa M.;
Anderson, Robyn;
Harman, Rebecca;
Muth, Aaron;
Thompson, Paul R.;
Coonrod, Scott A.;
Van de Walle, Gerlinde R.

Publication type:

journal article

Regulation of p53 Target Gene Expression by Peptidylarginine Deiminase 4.

Published in:

Molecular & Cellular Biology, 2008, v. 28, n. 15, p. 4745, doi. 10.1128/MCB.01747-07

By:

Pingxin Li;
Hongjie Yao;
Zhiqiang Zhang;
Ming Li;
Yuan Luo;
Thompson, Paul R.;
Gilmour, David S.;
Yanming Wang

Publication type:

Article

Citrullination of NF‐κB p65 by PAD2 as a Novel Therapeutic Target for Modulating Macrophage Polarization in Acute Lung Injury (Adv. Sci. 18/2025).

Published in:

Advanced Science, 2025, v. 12, n. 18, p. 1, doi. 10.1002/advs.202570132

By:

Yu, Xin;
Song, Yujing;
Dong, Tao;
Ouyang, Wenlu;
Quan, Chao;
Shao, Liujiazi;
Barasa, Leonard;
Thompson, Paul R.;
Zhang, Mao;
Ma, Jianjie;
Kurabayashi, Katsuo;
Li, Yongqing

Publication type:

Article

Citrullination of NF‐κB p65 by PAD2 as a Novel Therapeutic Target for Modulating Macrophage Polarization in Acute Lung Injury.

Published in:

Advanced Science, 2025, v. 12, n. 18, p. 1, doi. 10.1002/advs.202413253

By:

Yu, Xin;
Song, Yujing;
Dong, Tao;
Ouyang, Wenlu;
Quan, Chao;
Shao, Liujiazi;
Barasa, Leonard;
Thompson, Paul R.;
Zhang, Mao;
Ma, Jianjie;
Kurabayashi, Katsuo;
Li, Yongqing

Publication type:

Article

Site-specific incorporation of citrulline into proteins in mammalian cells.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20279-w

By:

Mondal, Santanu;
Wang, Shu;
Zheng, Yunan;
Sen, Sudeshna;
Chatterjee, Abhishek;
Thompson, Paul R.

Publication type:

Article

Potential Role of Peptidylarginine Deiminase Enzymes and Protein Citrullination in Cancer Pathogenesis.

Published in:

Biotechnology Research International, 2012, p. 1, doi. 10.1155/2012/895343

By:

Mohanan, Sunish;
Cherrington, Brian D.;
Horibata, Sachi;
McElwee, John L.;
Thompson, Paul R.;
Coonrod, Scott A.

Publication type:

Article

Inhibiting PAD2 enhances the anti-tumor effect of docetaxel in tamoxifen-resistant breast cancer cells.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2019, v. 38, n. 1, p. N.PAG, doi. 10.1186/s13046-019-1404-8

By:

Li, Fujun;
Miao, Lixia;
Xue, Teng;
Qin, Hao;
Mondal, Santanu;
Thompson, Paul R.;
Coonrod, Scott A.;
Liu, Xiaoqiu;
Zhang, Xuesen

Publication type:

Article

GnRH Induces Citrullination of the Cytoskeleton in Murine Gonadotrope Cells.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 6, p. 3181, doi. 10.3390/ijms25063181

By:

Quigley, Elizabeth B.;
DeVore, Stanley B.;
Khan, Shaihla A.;
Geisterfer, Zachary M.;
Rothfuss, Heather M.;
Sequoia, Ari O.;
Thompson, Paul R.;
Gatlin, Jesse C.;
Cherrington, Brian D.;
Navratil, Amy M.

Publication type:

Article

Identification and Characterization of the Lactating Mouse Mammary Gland Citrullinome.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 7, p. 2634, doi. 10.3390/ijms21072634

By:

Li, Guangyuan;
Young, Coleman H.;
Snow, Bryce;
Christensen, Amanda O.;
Demoruelle, M. Kristen;
Nemmara, Venkatesh V.;
Thompson, Paul R.;
Rothfuss, Heather M.;
Cherrington, Brian D.

Publication type:

Article

Peptidylarginine Deiminase Isozyme-Specific PAD2, PAD3 and PAD4 Inhibitors Differentially Modulate Extracellular Vesicle Signatures and Cell Invasion in Two Glioblastoma Multiforme Cell Lines.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 4, p. 1495, doi. 10.3390/ijms21041495

By:

Uysal-Onganer, Pinar;
MacLatchy, Amy;
Mahmoud, Rayan;
Kraev, Igor;
Thompson, Paul R.;
Inal, Jameel M.;
Lange, Sigrun

Publication type:

Article

Chloramidine/Bisindolylmaleimide-I-Mediated Inhibition of Exosome and Microvesicle Release and Enhanced Efficacy of Cancer Chemotherapy.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 5, p. 1007, doi. 10.3390/ijms18051007

By:

Kosgodage, Uchini S.;
Trindade, Rita P.;
Thompson, Paul R.;
Inal, Jameel M.;
Lange, Sigrun

Publication type:

Article

Potential role for PADI-mediated histone citrullination in preimplantation development.

Published in:

BMC Developmental Biology, 2012, v. 12, n. 1, p. 19, doi. 10.1186/1471-213X-12-19

By:

Rui Kan;
Mei Jin;
Subramanian, Venkataraman;
Causey, Corey P.;
Thompson, Paul R.;
Coonrod, Scott A.

Publication type:

Article

Role of peptidylarginine deiminase 2 (PAD2) in mammary carcinoma cell migration.

Published in:

2017

By:

Sachi Horibata;
Rogers, Katherine E.;
Sadegh, David;
Anguish, Lynne J.;
McElwee, John L.;
Shah, Pragya;
Thompson, Paul R.;
Coonrod, Scott A.;
Horibata, Sachi

Publication type:

journal article

Halogen Bonding Increases the Potency and Isozyme Selectivity of Protein Arginine Deiminase 1 Inhibitors.

Published in:

Angewandte Chemie, 2019, v. 131, n. 36, p. 12606, doi. 10.1002/ange.201906334

By:

Mondal, Santanu;
Gong, Xuefeng;
Zhang, Xiaoqian;
Salinger, Ari J.;
Zheng, Li;
Sen, Sudeshna;
Weerapana, Eranthie;
Zhang, Xuesen;
Thompson, Paul R.

Publication type:

Article

DEVELOPMENT OF STANDARDIZATION AND HARMONIZED ADVERTISING REGULATION IN THE EUROPEAN ECONOMIC COMMUNITY.

Published in:

Journal of Advertising, 1985, v. 14, n. 2, p. 23, doi. 10.1080/00913367.1985.10672943

By:

Greer, Thomas V.;
Thompson, Paul R.

Publication type:

Article

Activation of PAD4 in NET formation.

Published in:

Frontiers in Immunology, 2012, v. 3, p. 1, doi. 10.3389/fimmu.2012.00360

By:

Rohrbach, Amanda S.;
Slade, Daniel J.;
Thompson, Paul R.;
Mowen, Kerri A.

Publication type:

Article

PLC and PAD2 Regulate Extracellular Calcium‐Triggered Release of Macrophage Extracellular DNA Traps.

Published in:

European Journal of Immunology, 2025, v. 55, n. 4, p. 1, doi. 10.1002/eji.202350942

By:

Mishra, Neha;
Mohs, Magdalena;
Wittmann, Nico;
Gross, Stefan;
Thompson, Paul R.;
Bossaller, Lukas

Publication type:

Article

Synthesis and Use of a Phosphonate Amidine to Generate an Anti- Phosphoarginine-Specific Antibody.

Published in:

Angewandte Chemie International Edition, 2015, v. 54, n. 49, p. 14715, doi. 10.1002/anie.201506737

By:

Fuhrmann, Jakob;
Subramanian, Venkataraman;
Thompson, Paul R.

Publication type:

Article

Synthesis and Use of a Phosphonate Amidine to Generate an Anti-Phosphoarginine-Specific Antibody.

Published in:

Angewandte Chemie, 2015, v. 127, n. 49, p. 14928, doi. 10.1002/ange.201506737

By:

Fuhrmann, Jakob;
Subramanian, Venkataraman;
Thompson, Paul R.

Publication type:

Article

Response to comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis".

Published in:

Science Immunology, 2018, v. 3, n. 21, p. 1, doi. 10.1126/sciimmunol.aar3701

By:

Carmona-Rivera, Carmelo;
Bicker, Kevin L.;
Thompson, Paul R.;
Buckner, Jane H.;
Robinson, William H.;
Fox, David A.;
Kaplan, Mariana J.

Publication type:

Article

Citrullination of NF-κB p65 promotes its nuclear localization and TLR-induced expression of IL-1β and TNFα.

Published in:

Science Immunology, 2017, v. 2, n. 12, p. 1, doi. 10.1126/sciimmunol.aal3062

By:

Sun, Bo;
Dwivedi, Nishant;
Bechtel, Tyler J.;
Paulsen, Janet L.;
Muth, Aaron;
Bawadekar, Mandar;
Li, Gang;
Thompson, Paul R.;
Shelef, Miriam A.;
Schiffer, Celia A.;
Weerapana, Eranthie;
Ho, I-Cheng

Publication type:

Article

Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis.

Published in:

Science Immunology, 2017, v. 2, n. 10, p. 1, doi. 10.1126/sciimmunol.aag3358

By:

Carmona-Rivera, Carmelo;
Carlucci, Philip M.;
Moore, Erica;
Lingampalli, Nithya;
Uchtenhagen, Hannes;
James, Eddie;
Yudong Liu;
Bicker, Kevin L.;
Wahamaa, Heidi;
Hoffmann, Victoria;
Catrina, Anca Irinel;
Thompson, Paul R.;
Buckner, Jane H.;
Robinson, William H.;
Fox, David A.;
Kaplan, Mariana J.

Publication type:

Article

Neutrophil Extracellular Trap-Derived Enzymes Oxidize High-Density Lipoprotein: An Additional Proatherogenic Mechanism in Systemic Lupus Erythematosus.

Published in:

Arthritis & Rheumatology, 2014, v. 66, n. 9, p. 2532, doi. 10.1002/art.38703

By:

Smith, Carolyne K.;
Vivekanandan‐Giri, Anuradha;
Tang, Chongren;
Knight, Jason S.;
Mathew, Anna;
Padilla, Robin L.;
Gillespie, Brenda W.;
Carmona‐Rivera, Carmelo;
Liu, Xiaodan;
Subramanian, Venkataraman;
Hasni, Sarfaraz;
Thompson, Paul R.;
Heinecke, Jay W.;
Saran, Rajiv;
Pennathur, Subramaniam;
Kaplan, Mariana J.

Publication type:

Article

A phase transition enhances the catalytic activity of SARM1, an NAD<sup>+</sup> glycohydrolase involved in neurodegeneration.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.66694

By:

Loring, Heather S.;
Czech, Victoria L.;
Icso, Janneke D.;
O'Connor, Lauren;
Parelkar, Sangram S.;
Byrne, Alexandra B.;
Thompson, Paul R.

Publication type:

Article