Works matching DE "INTEGRASE inhibitors"

Results: 445

Identification of Influenza PA N Endonuclease Inhibitors via 3D-QSAR Modeling and Docking-Based Virtual Screening.

Published in:

Molecules, 2021, v. 26, n. 23, p. 7129, doi. 10.3390/molecules26237129

By:

Zhang, Chao;
Xiang, Junjie;
Xie, Qian;
Zhao, Jing;
Zhang, Hong;
Huang, Erfang;
Shaw, Pangchui;
Liu, Xiaoping;
Hu, Chun

Publication type:

Article

Studies towards the Design and Synthesis of Novel 1,5-Diaryl-1 H -imidazole-4-carboxylic Acids and 1,5-Diaryl-1 H -imidazole-4-carbohydrazides as Host LEDGF/p75 and HIV-1 Integrase Interaction Inhibitors.

Published in:

Molecules, 2021, v. 26, n. 20, p. 6203, doi. 10.3390/molecules26206203

By:

Rashamuse, Thompho J.;
Fish, Muhammad Q.;
Coyanis, E. Mabel;
Bode, Moira L.

Publication type:

Article

Discovery of Novel Integrase Inhibitors Acting outside the Active Site Through High-Throughput Screening.

Published in:

Molecules, 2019, v. 24, n. 20, p. 3675, doi. 10.3390/molecules24203675

By:

Aknin, Cindy;
Smith, Elena A.;
Marchand, Christophe;
Andreola, Marie-Line;
Pommier, Yves;
Metifiot, Mathieu

Publication type:

Article

Synthesis and Anti-HIV-1 Activity Evaluation for Novel 3a,6a-Dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives.

Published in:

Molecules, 2016, v. 21, n. 9, p. 1198, doi. 10.3390/molecules21091198

By:

Guan-Nan Liu;
Rong-Hua Luo;
Yu Zhou;
Xing-Jie Zhang;
Jian Li;
Liu-Meng Yang;
Yong-Tang Zheng;
Hong Liu

Publication type:

Article

Integrase Inhibitor Prodrugs: Approaches to Enhancing the Anti-HIV Activity of â-Diketo Acids.

Published in:

Molecules, 2015, v. 20, n. 7, p. 12623, doi. 10.3390/molecules200712623

By:

Nair, Vasu;
Okello, Maurice

Publication type:

Article

Formulation And Evaluation Of Dolutegravir Mouth Dissolving Thin Films.

Published in:

Frontiers in Health Informatics, 2024, v. 13, n. 4, p. 609

By:

Kakullamarri, Praneeth Rao;
Babu, K. Suresh

Publication type:

Article

HIV Pretreatment Drug Resistance Trends in Mexico City, 2017–2020.

Published in:

Pathogens, 2021, v. 10, n. 12, p. 1587, doi. 10.3390/pathogens10121587

By:

García-Morales, Claudia;
Tapia-Trejo, Daniela;
Matías-Florentino, Margarita;
Quiroz-Morales, Verónica Sonia;
Dávila-Conn, Vanessa;
Beristain-Barreda, Ángeles;
Cárdenas-Sandoval, Miroslava;
Becerril-Rodríguez, Manuel;
Iracheta-Hernández, Patricia;
Macías-González, Israel;
García-Mendiola, Rebecca;
Guzmán-Carmona, Alejandro;
Zarza-Sánchez, Eduardo;
Cruz, Raúl Adrián;
González-Rodríguez, Andrea;
Reyes-Terán, Gustavo;
Ávila-Ríos, Santiago

Publication type:

Article

The Combination of Molnupiravir with Nirmatrelvir or GC376 Has a Synergic Role in the Inhibition of SARS-CoV-2 Replication In Vitro.

Published in:

Microorganisms, 2022, v. 10, n. 7, p. N.PAG, doi. 10.3390/microorganisms10071475

By:

Gidari, Anna;
Sabbatini, Samuele;
Schiaroli, Elisabetta;
Bastianelli, Sabrina;
Pierucci, Sara;
Busti, Chiara;
Comez, Lucia;
Libera, Valeria;
Macchiarulo, Antonio;
Paciaroni, Alessandro;
Vicenti, Ilaria;
Zazzi, Maurizio;
Francisci, Daniela

Publication type:

Article

Absence of Resistance Mutations in the Integrase Coding Region among ART-Experienced Patients in the Republic of the Congo.

Published in:

Microorganisms, 2021, v. 9, n. 11, p. 2355, doi. 10.3390/microorganisms9112355

By:

Got, Ferdinand Emaniel Brel;
Recordon-Pinson, Patricia;
Loubano-Voumbi, Ghislain;
Ebourombi, Dagene;
Blondot, Marie-Lise;
Metifiot, Mathieu;
Ondzotto, Gontran;
Andreola, Marie-Line

Publication type:

Article

Switching to Integrase Inhibitors Unlinked to Weight Increase in Perinatally HIV-Infected Young Adults and Adolescents: A 10-Year Observational Study.

Published in:

Microorganisms, 2020, v. 8, n. 6, p. 864, doi. 10.3390/microorganisms8060864

By:

Taramasso, Lucia;
Di Biagio, Antonio;
Bovis, Francesca;
Forlanini, Federica;
Albani, Elena;
Papaioannu, Rebecka;
Giacomet, Vania

Publication type:

Article

Role of Human Papillomavirus (HPV), Estrogen and Apobec3B Axis in Breast Cancer Initation.

Published in:

Malaysian Journal of Medicine & Health Sciences, 2017, v. 13, p. 14

By:

Ohba, Kenji;
Pei Pei Chong;
Naoki Yamamoto

Publication type:

Article

Diabetes mellitus in patients with HIV naïve to antiretroviral therapy initiating integrase inhibitors therapy.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-02688-3

By:

Dias da Costa, Sara;
Bichança, Ema;
Cruz, Filipe;
Guimarães, André Rodrigues;
Piñeiro, Carmela;
Santos-Sousa, Hugo;
Serrão, Rosário;
Freitas, Paula

Publication type:

Article

Clinical Outcomes of Integrase Strand Transfer Inhibitors Containing Antiretroviral Therapy in HIV-2: A Narrative Review.

Published in:

Infectious Diseases & Therapy, 2024, v. 13, n. 6, p. 1161, doi. 10.1007/s40121-024-00982-7

By:

Boschloo, Wendy J.;
van Welzen, Berend J.

Publication type:

Article

Integrase Inhibitors Partially Restore Bacterial Translocation, Inflammation and Gut Permeability Induced by HIV Infection: Impact on Gut Microbiota.

Published in:

Infectious Diseases & Therapy, 2022, v. 11, n. 4, p. 1541, doi. 10.1007/s40121-022-00654-4

By:

Villoslada-Blanco, Pablo;
Pérez-Matute, Patricia;
Íñiguez, María;
Recio-Fernández, Emma;
Blanco-Navarrete, Pilar;
Metola, Luis;
Ibarra, Valvanera;
Alba, Jorge;
de Toro, María;
Oteo, José A.

Publication type:

Article

Novel Naturally Occurring Dipeptides and Single-Stranded Oligonucleotide Act as Entry Inhibitors and Exhibit a Strong Synergistic Anti-HIV-1 Profile.

Published in:

Infectious Diseases & Therapy, 2022, v. 11, n. 3, p. 1103, doi. 10.1007/s40121-022-00626-8

By:

Ceña-Diez, Rafael;
Singh, Kamalendra;
Spetz, Anna-Lena;
Sönnerborg, Anders

Publication type:

Article

A Single-Center Retrospective Cohort Analysis of Maternal and Infant Outcomes in HIV-Infected Mothers Treated with Integrase Inhibitors During Pregnancy.

Published in:

Infectious Diseases & Therapy, 2017, v. 6, n. 4, p. 531, doi. 10.1007/s40121-017-0170-1

By:

Mounce, Monique;
Pontiggia, Laura;
Adams, Jessica

Publication type:

Article

FNC: An Advanced Anticancer Therapeutic or Just an Underdog?

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.820647

By:

Fayzullina, Daria;
Kharwar, Rajesh Kumar;
Acharya, Arbind;
Buzdin, Anton;
Borisov, Nicolas;
Timashev, Peter;
Ulasov, Ilya;
Kapomba, Byron

Publication type:

Article

Assessing HIV-1 subtype C infection dynamics, therapeutic responses and reservoir distribution using a humanized mouse model.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1552563

By:

Kaginkar, Snehal;
Remling-Mulder, Leila;
Sahoo, Ashashree;
Pandey, Tejaswini;
Gurav, Pranay;
Sutar, Jyoti;
Singh, Amit Kumar;
Barnett, Ella;
Panickan, Sivasankar;
Akkina, Ramesh;
Patel, Vainav

Publication type:

Article

Changes to inflammatory markers during 5 years of viral suppression and during viral blips in people with HIV initiating different integrase inhibitor based regimens.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1488799

By:

Funderburg, Nicholas T.;
Huang, Susie S. Y.;
Cohen, Calvin;
Ailstock, Kate;
Cummings, Morgan;
Lee, Jean C.;
Ng, Brenda;
White, Kirsten;
Wallin, Jeffrey J.;
Downie, Bryan;
McComsey, Grace A.

Publication type:

Article

Long-term effects on immunological, inflammatory markers, and HIV-1 reservoir after switching to a two-drug versus maintaining a three-drug regimen based on integrase inhibitors.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1423734

By:

Saborido-Alconchel, Abraham;
Serna-Gallego, Ana;
Trujillo-Rodriguez, María;
Muñoz-Muela, Esperanza;
Álvarez-Ríos, Ana I.;
Lozano, Carmen;
Llaves-Flores, Silvia;
Espinosa, Nuria;
Roca-Oporto, Cristina;
Herrero, Marta;
Sotomayor, Cesar;
Gutierrez-Valencia, Alicia;
Lopez-Cortes, Luis F.

Publication type:

Article

Primary and secondary resistance of HIV-1 to integrase inhibitors in Cuban patients infected with multidrug-resistant HIV strains.

Published in:

Journal of Microbiology & Infectious Diseases, 2023, v. 13, n. 2, p. 72, doi. 10.5455/JMID.2023.v13.i2.4

By:

Pintos-Saavedra, Yanet;
Pérez-Santos, Lissette;
Kourí-Cardellá, Vivian;
González, Melissa Méndez;
Pintos, Jaime;
Perez, Jorge;
Gómez, Carlos Fonseca;
Guilarte, Elias;
Brito, Yudira Soto;
Morales, Yoanna Baños;
Fernandez, Karla

Publication type:

Article

Bictegravir/Tenofovir Alafenamide/Emtricitabine: A Real-Life Experience in People Living with HIV (PLWH).

Published in:

Infectious Disease Reports, 2023, v. 15, n. 6, p. 766, doi. 10.3390/idr15060069

By:

Gidari, Anna;
Benedetti, Sara;
Tordi, Sara;
Zoffoli, Anastasia;
Altobelli, Debora;
Schiaroli, Elisabetta;
De Socio, Giuseppe Vittorio;
Francisci, Daniela

Publication type:

Article

Emergence of the G118R Pan-Integrase Resistance Mutation as a Result of Low Compliance to a Dolutegravir-Based cART.

Published in:

Infectious Disease Reports, 2022, v. 14, n. 4, p. 501, doi. 10.3390/idr14040053

By:

Mens, Helene;
Fjordside, Lasse;
Fonager, Jannik;
Gerstoft, Jan

Publication type:

Article

Hyperbaric hyperoxia exposure in suppressing human immunodeficiency virus replication: An experimental in vitro in peripheral mononuclear blood cells culture.

Published in:

Infectious Disease Reports, 2020, v. 12, p. 88, doi. 10.4081/idr.2020.8743

By:

Budiarti, Retno;
Khairunisa, Siti Qamariyah;
Nasronudin;
Kuntaman;
Guritno

Publication type:

Article

A quantitative structure–activity relationship study on HIV-1 integrase inhibitors using genetic algorithm, artificial neural networks and different statistical methods.

Published in:

Arabian Journal of Chemistry, 2016, v. 9, p. S185, doi. 10.1016/j.arabjc.2011.03.006

By:

Ghasemi, Ghasem;
Nirouei, Mahyar;
Shariati, Shahab;
Abdolmaleki, Parviz;
Rastgoo, Zinab

Publication type:

Article

Prevalence of resistance mutations associated with integrase inhibitors in therapy-naive HIV-positive patients in Hungary.

Published in:

Acta Microbiologica et Immunologica Hungarica, 2021, v. 68, n. 2, p. 87, doi. 10.1556/030.2021.01433

By:

Farzi, Sorour;
Rezazadeh, Mohsen;
Mirhosseini, Ahmadreza;
Rezazadeh, Mohammad Amin;
Houshyar, Farhan;
Ahmadi, Mohammad Hossein

Publication type:

Article

Genotyping and outcomes of presumptive second line ART failure cases switched to third line or maintained on second line ART in Mumbai, India.

Published in:

PLoS ONE, 2019, v. 14, n. 11, p. 1, doi. 10.1371/journal.pone.0225631

By:

Gill, Naresh;
Van den Bergh, Rafael;
Wut Yee Kyaw, Khine;
Laxmeshwar, Chinmay;
Das, Mrinalini;
Rastogi, Sarthak;
Arago Galindo, Miriam;
Mansoor, Homa;
Kalon, Stobdan;
Isaakidis, Petros

Publication type:

Article

Elderly HIV-positive women: A gender-based analysis from the Multicenter Italian "GEPPO" Cohort.

Published in:

PLoS ONE, 2019, v. 14, n. 10, p. 1, doi. 10.1371/journal.pone.0222225

By:

Focà, Emanuele;
Magro, Paola;
Guaraldi, Giovanni;
Riva, Agostino;
Cattelan, Anna Maria;
De Socio, Giuseppe Vittorio;
Costa, Cecilia;
Piconi, Stefania;
Celesia, Benedetto Maurizio;
Nozza, Silvia;
Orofino, Giancarlo;
Castagna, Antonella;
Di Perri, Giovanni;
Castelli, Francesco;
Calcagno, Andrea

Publication type:

Article

Choice of the initial antiretroviral treatment for HIV-positive individuals in the era of integrase inhibitors.

Published in:

PLoS ONE, 2019, v. 14, n. 8, p. 1, doi. 10.1371/journal.pone.0221598

By:

Alejos, Belén;
Suárez-García, Inés;
Bisbal, Otilia;
Iribarren, José Antonio;
Asensi, Víctor;
Górgolas, Miguel;
Muga, Roberto;
Moreno, Santiago;
Jarrín, Inma;
null, null

Publication type:

Article

PRODUCTS ETHICAL.

Published in:: 2022
Publication type:: Product Review

Might dolutegravir be part of a functional cure for HIV?<sup>1</sup>.

Published in:

Canadian Journal of Microbiology, 2016, v. 62, n. 5, p. 375, doi. 10.1139/cjm-2015-0725

By:

Wainberg, Mark A.;
Han, Ying-Shan;
Mesplède, Thibault

Publication type:

Article

Metformin‐sensitized NSCLC cells to osimertinib via AMPK‐dependent autophagy inhibition.

Published in:

Clinical Respiratory Journal, 2019, v. 13, n. 12, p. 781, doi. 10.1111/crj.13091

By:

Chen, Hengyi;
Lin, Caiyu;
Lu, Conghua;
Wang, Yubo;
Han, Rui;
Li, Li;
Hao, Shuai;
He, Yong

Publication type:

Article

Gut microbiota from Mexican patients with metabolic syndrome and HIV infection: An inflammatory profile.

Published in:

Journal of Applied Microbiology, 2022, v. 132, n. 5, p. 3839, doi. 10.1111/jam.15505

By:

Amador‐Lara, Fernando;
Andrade‐Villanueva, Jaime F.;
Vega‐Magaña, Natali;
Peña‐Rodríguez, Marcela;
Alvarez‐Zavala, Monserrat;
Sanchez‐Reyes, Karina;
Toscano‐Piña, Marcela;
Peregrina‐Lucano, Alejandro A.;
del Toro‐Arreola, Susana;
González‐Hernández, Luz A.;
Bueno‐Topete, Miriam R.

Publication type:

Article

A Reduced Grade of Liver Fibro-steatosis after Raltegravir, Maraviroc and Fosamprenavir in an HIV/HCV Co-infected Patient with Chronic Hepatitis, Cardiomyopathy, Intolerance to Nelfinavir and a Marked Increase of Serum Creatine Phosphokinase Levels Probably Related to Integrase Inhibitor Use

Published in:

West Indian Medical Journal, 2012, v. 61, n. 9, p. 932, doi. 10.7727/wimj.2011.194

By:

Antoni, A Degli;
Weimer, L. E.;
Manfredi, R.;
Fragola, V.;
Ferrari, C.

Publication type:

Article

Immune checkpoint inhibitor therapy for cancer patients infected with HIV: A systematic review.

Published in:

Asia Pacific Journal of Clinical Oncology, 2022, v. 18, n. 2, p. e17, doi. 10.1111/ajco.13320

By:

Luo, Ling;
Xu, Yan;
Li, Taisheng

Publication type:

Article

Dolutegravir-induced hand-foot skin reaction in a seropositive male: A rare presentation.

Published in:

Indian Journal of Pharmacology, 2024, v. 56, n. 1, p. 55, doi. 10.4103/ijp.ijp_258_23

By:

Gayen, Tirthankar;
Baisya, Subhasmita;
Sarawgi, Devansi;
Sen, Sumit

Publication type:

Article

The Discovery of Indole-2-carboxylic Acid Derivatives as Novel HIV-1 Integrase Strand Transfer Inhibitors.

Published in:

Molecules, 2023, v. 28, n. 24, p. 8020, doi. 10.3390/molecules28248020

By:

Wang, Yu-Chan;
Zhang, Wen-Li;
Zhang, Rong-Hong;
Liu, Chun-Hua;
Zhao, Yong-Long;
Yan, Guo-Yi;
Liao, Shang-Gao;
Li, Yong-Jun;
Zhou, Meng

Publication type:

Article

Development of H51Y and E157Q mutations for integrase inhibitor resistance in a patient undergoing treatment for pulmonary tuberculosis: A case report.

Published in:

2023

By:

Farias, Luís Arthur Brasil Gadelha;
Saboya, Melissa Fiuza;
Ponte Fernandes, Natália;
Perdigão Neto, Lauro Vieira;
de Arruda, Erico Antonio Gomes

Publication type:

Case Study

针对人类免疫缺陷病毒结构蛋白 Gag-Pol的抑制剂及其作用机制研究进展.

Published in:

Journal of Jilin University (Medicine Edition), 2024, v. 50, n. 4, p. 1156, doi. 10.13481/j.1671-587X.202404032

By:

黄国锋;
李聪宜;
王虹;
张文艳

Publication type:

Article

Circulating levels of transforming growth factor beta-1, 2 and 3 in HIV associated preeclamptic pregnancies.

Published in:

Journal of Obstetrics & Gynaecology, 2022, v. 42, n. 7, p. 2853, doi. 10.1080/01443615.2022.2110458

By:

Mtshali, Zamahlabangane;
Govender, Nalini;
Naicker, Thajasvarie

Publication type:

Article

Clinical trial of raltegravir, an integrase inhibitor, in HAM/TSP.

Published in:

Annals of Clinical & Translational Neurology, 2021, v. 8, n. 10, p. 1970, doi. 10.1002/acn3.51437

By:

Enose‐Akahata, Yoshimi;
Billioux, Bridgette Jeanne;
Azodi, Shila;
Dwyer, Jennifer;
Vellucci, Ashley;
Ngouth, Nyater;
Nozuma, Satoshi;
Massoud, Raya;
Cortese, Irene;
Ohayon, Joan;
Jacobson, Steven

Publication type:

Article

Hydroxychloroquine Effects on TLR Signalling: Underexposed but Unneglectable in COVID-19.

Published in:

Journal of Immunology Research, 2021, p. 1, doi. 10.1155/2021/6659410

By:

in 't Veld, Aliede E.;
Jansen, Manon A. A.;
Ciere, Luuk C. A.;
Moerland, Matthijs

Publication type:

Article

The Potential of Long-Acting, Injectable PrEP, and Impediments to its Uptake.

Published in:

Journal of Urban Health, 2023, v. 100, n. 1, p. 212, doi. 10.1007/s11524-022-00711-w

By:

Miller, Amitai S.;
Krakower, Douglas S.;
Mayer, Kenneth H.

Publication type:

Article

Specific Deubiquitinating Enzymes Promote Host Restriction Factors Against HIV/SIV Viruses.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.740713

By:

Gao, Wenying;
Rui, Yajuan;
Li, Guangquan;
Zhai, Chenyang;
Su, Jiaming;
Liu, Han;
Zheng, Wenwen;
Zheng, Baisong;
Zhang, Wenyan;
Yang, Yongjun;
Hua, Shucheng;
Yu, Xiaofang

Publication type:

Article

The Effect of JAK1/2 Inhibitors on HIV Reservoir Using Primary Lymphoid Cell Model of HIV Latency.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.720697

By:

de Armas, Lesley R.;
Gavegnano, Christina;
Pallikkuth, Suresh;
Rinaldi, Stefano;
Pan, Li;
Battivelli, Emilie;
Verdin, Eric;
Younis, Ramzi T.;
Pahwa, Rajendra;
Williams, Siôn L.;
Schinazi, Raymond F.;
Pahwa, Savita

Publication type:

Article

Cathepsins and Their Endogenous Inhibitors in Host Defense During Mycobacterium tuberculosis and HIV Infection.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.726984

By:

Anes, Elsa;
Azevedo-Pereira, José Miguel;
Pires, David

Publication type:

Article

Contribution of Adipose Tissue to the Chronic Immune Activation and Inflammation Associated With HIV Infection and Its Treatment.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.670566

By:

Bourgeois, Christine;
Gorwood, Jennifer;
Olivo, Anaelle;
Le Pelletier, Laura;
Capeau, Jacqueline;
Lambotte, Olivier;
Béréziat, Véronique;
Lagathu, Claire

Publication type:

Article

Physiologically Relevant Concentrations of Dolutegravir, Emtricitabine, and Efavirenz Induce Distinct Metabolic Alterations in HeLa Epithelial and BV2 Microglial Cells.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.639378

By:

George, Joseph W.;
Mattingly, Jane E.;
Roland, Nashanthea J.;
Small, Cassandra M.;
Lamberty, Benjamin G.;
Fox, Howard S.;
Stauch, Kelly L.

Publication type:

Article

Drug resistance mutations to integrase inhibitors, proteinase, and reverse transcriptase inhibitors in newly diagnosed HIV-1 infections in Hebei province, China, 2018–2022.

Published in:

Frontiers in Cellular & Infection Microbiology, 2025, p. 1, doi. 10.3389/fcimb.2025.1510916

By:

Lu, Xinli;
Li, Yan;
Liu, Meng;
Wang, Yingying;
An, Ning;
Sun, Dandan;
Li, Qi

Publication type:

Article

CD8<sup>+</sup> T cells control SIV infection using both cytolytic effects and non-cytolytic suppression of virus production.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42435-8

By:

Policicchio, Benjamin B.;
Cardozo-Ojeda, Erwing Fabian;
Xu, Cuiling;
Ma, Dongzhu;
He, Tianyu;
Raehtz, Kevin D.;
Sivanandham, Ranjit;
Kleinman, Adam J.;
Perelson, Alan S.;
Apetrei, Cristian;
Pandrea, Ivona;
Ribeiro, Ruy M.

Publication type:

Article