Works matching DE "PROTEOLYSIS"

Results: 5000

Microbial Peptidases: Key Players in Reducing Gluten Immunogenicity Through Peptide Degradation.

Published in:

Applied Sciences (2076-3417), 2025, v. 15, n. 14, p. 8111, doi. 10.3390/app15148111

By:

Sanchiz, Africa;
San-Martín, M. Isabel;
Navasa, N.;
Martínez-Blanco, Honorina;
Ferrero, Miguel Ángel;
Rodríguez-Aparicio, Leandro Benito;
Chamizo-Ampudia, Alejandro

Publication type:

Article

Four Dairy Products Mitigates Sarcopenia in Mice by Modulating Muscle Inflammation, Autophagy, and Protein Degradation.

Published in:

Food Science & Nutrition, 2025, v. 13, n. 7, p. 1, doi. 10.1002/fsn3.70540

By:

Sun, Meng;
Wu, Tong;
Wang, Ruoyu;
Ma, Yuxin;
Han, Yaxin;
Hou, Yanmei;
Zhang, Zhaofeng

Publication type:

Article

Untargeted metabolomics depicts the chemical changes of PDO dry-cured Parma Ham during different processing stages.

Published in:

Metabolomics, 2025, v. 21, n. 4, p. 1, doi. 10.1007/s11306-025-02283-7

By:

Rocchetti, Gabriele;
Senizza, Biancamaria;
Becchi, Pier Paolo;
Dallolio, Michele;
Lucini, Luigi

Publication type:

Article

Protease Enzyme Supplementation in Weaning Piglets Fed Reduced Crude Protein Diets: Effects on Gut Health Integrity and Performance Response.

Published in:

Animals (2076-2615), 2025, v. 15, n. 14, p. 2109, doi. 10.3390/ani15142109

By:

Furlani, Nathana Rudio;
Da Motta, Stephane Alverina Briguente;
Ramos, Bruno Teixeira;
Fernandes, Wender Vieira;
de Farias, Maria Rogervânia Silva;
Riveros, Rony;
Tizziani, Tarciso;
Hannas, Melissa Izabel

Publication type:

Article

Tumour initiated purinergic signalling promotes cardiomyocyte RBFOX1 degradation and cardiotoxicity from DNA damaging anticancer agents.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-62172-4

By:

Tejay, Saymon;
Lorenzana-Carrillo, Maria Areli;
Huang, Guocheng;
Tabatabaei Dakhili, Seyed Amirhossein;
Zhao, Yuan -Yuan;
Eaton, Farah;
Mendiola Pla, Michelle;
Bowles, Dawn E.;
Kinnaird, Adam;
Paterson, D. Ian;
Pituskin, Edith;
Ussher, John R.;
Michelakis, Evangelos D.;
Sutendra, Gopinath

Publication type:

Article

Seed-Specific Silencing of Abundantly Expressed Soybean Bowman–Birk Protease Inhibitor Genes by RNAi Lowers Trypsin and Chymotrypsin Inhibitor Activities and Enhances Protein Digestibility.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 14, p. 6943, doi. 10.3390/ijms26146943

By:

Kim, Wonseok;
Kim, Sunhyung;
Krishnan, Hari B.

Publication type:

Article

A New GlyT2 Variant Associated with Hyperekplexia.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 14, p. 6753, doi. 10.3390/ijms26146753

By:

Sarmiento-Jiménez, Jorge;
Felipe, Raquel;
Núñez, Enrique;
Ferrando-Muñoz, Alejandro;
Benito-Muñoz, Cristina;
Gago, Federico;
Vázquez, Jesús;
Camafeita, Emilio;
Clement, Emma;
Wilson, Brian;
López-Corcuera, Beatriz

Publication type:

Article

Targeted Degradation Technologies Utilizing Autophagy.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 14, p. 6576, doi. 10.3390/ijms26146576

By:

Zhou, Zeyu;
Liang, Jiaming;
Cheng, Binghua;
Li, Yanyan;
Zhou, Wenjie;
Tian, Hui;
Shi, Wenli;
Liu, Ke;
Fang, Lijing;
Li, Hongchang;
Shao, Ximing

Publication type:

Article

Storage Stability and Biochemical Changes of the Common Carp Slices Treated With Carotenoid Extracted from Crayfish Waste.

Published in:

Egyptian Journal of Aquatic Biology & Fisheries, 2025, v. 29, n. 4, p. 359, doi. 10.21608/ejabf.2025.440423

By:

Ibrahim, Mohamed A.;
El-Deeb, Fadel A.;
El-Bassiouni, Ghada M.;
El-Aiedy, Heba M.

Publication type:

Article

Angiotensin II Type 1 Receptor Blocker Usage Prevents Oxidative Stress and Muscle Dysfunction in HIV.

Published in:

Fundamental & Clinical Pharmacology, 2025, v. 39, n. 4, p. 1, doi. 10.1111/fcp.70016

By:

Deminice, Rafael;
Cella, Paola Sanches;
Borsari, Ana Lúcia;
Padilha, Camila S.;
de Oliveira, Vitor Hugo Fernando

Publication type:

Article

Integration of sprouting and extrusion for development of legume-cereal-based pasta.

Published in:

International Food Research Journal, 2025, v. 32, n. 2, p. 591, doi. 10.47836/ifrj.32.2.21

By:

Sethi, S.;
Mridula, D.;
Kumar, P.

Publication type:

Article

PROTAC : Nouvelles stratégies thérapeutiques basées sur l'exploitation des voies de dégradation des protéines.

Published in:

Biologie Aujourd'hui, 2024, v. 218, n. 3/4, p. 105, doi. 10.1051/jbio/2024010

By:

Cornu, Marie;
Lemaitre, Thomas;
Schwalen, Florian;
Kieffer, Charline;
Voisin-Chiret, Anne Sophie

Publication type:

Article

Deferoxamine prevents dexamethasone-induced muscle atrophy by reducing MuRF1 and atrogin-1.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1582216

By:

Jeong, Jae-Yeop;
Son, Youngho;
Kim, Youngha;
Lee, Nami;
Kim, Yujin;
Heo, Yu Jung;
Choi, Sung-E.;
Choi, Jaemyung;
Han, Seung Jin;
Jeon, Jayoung;
Kim, Hae Jin;
Lee, Kwan-Woo

Publication type:

Article

Pathogenesis and Current Treatment Strategies in Rheumatoid Arthritis: A Systematic Review Article.

Published in:

Annals of African Medicine, 2025, v. 24, n. 3, p. 532, doi. 10.4103/aam.aam_11_24

By:

Deka, Debajani

Publication type:

Article

A chaperonin complex regulates organelle proteostasis in malaria parasites.

Published in:

PLoS Pathogens, 2025, v. 21, n. 7, p. 1, doi. 10.1371/journal.ppat.1013275

By:

Tissawak, Amanda;
Rosin, Yarden;
Katz Galay, Shirly;
Qasem, Alia;
Shahar, Michal;
Trabelsi, Nirit;
Furman-Schueler, Ora;
Johnson, Steven M.;
Florentin, Anat

Publication type:

Article

A sphingomyelin shield for flaviviruses.

Published in:

2025

By:

Wong, Wei

Publication type:

Abstract

Coping with stress: the essential role of brain autophagy in emotional homeostasis.

Published in:

Autophagy, 2025, v. 21, n. 8, p. 1621, doi. 10.1080/15548627.2025.2520091

By:

Dialynaki, Dimitra;
Klionsky, Daniel J.

Publication type:

Article

Unraveling the complexity of chaperone-mediated autophagy in aging: insights into sex-specific and cell-type-specific regulation.

Published in:

Autophagy, 2025, v. 21, n. 8, p. 1848, doi. 10.1080/15548627.2025.2489530

By:

Luo, Rongcan

Publication type:

Article

Chaperone-mediated autophagy degrades SERPINA1<sup>E342K</sup>/α1-antitrypsin Z variant and alleviates cell stress.

Published in:

Autophagy, 2025, v. 21, n. 8, p. 1662, doi. 10.1080/15548627.2025.2480037

By:

Lin, Jiayu;
Wei, Xinyue;
Dai, Yan;
Lu, Haorui;
Song, Yajian;
Ju, Jiansong;
Wu, Rihan;
Cao, Qichen;
Yang, Hao;
Rao, Lang

Publication type:

Article

OICR-41103 as a chemical probe for the DCAF1 WD40 domain.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08491-0

By:

Kimani, Serah W.;
Noureldin, Mahmoud;
Wilson, Brian;
Hoffer, Laurent;
Green, Stuart R.;
Szewczyk, Magdalena M.;
González-Álvarez, Héctor;
Mohammed, Mohammed;
Chan, Manuel;
Krausser, Chiara;
Li, Alice Shi Ming;
Hajian, Taraneh;
Tucker, Sarah;
Joshi, Dhananjay;
Saraon, Punit;
Thériault, Brigitte;
Kim, Ji Sup;
Santhakumar, Vijayaratnam;
Loppnau, Peter;
Li, Yanjun

Publication type:

Article

A Plug‐and‐Play Ferritac Platform Degrading Membrane Proteins via Receptor Crosslinking.

Published in:

Advanced Functional Materials, 2025, v. 35, n. 28, p. 1, doi. 10.1002/adfm.202420004

By:

He, Qunye;
Wang, Lei;
Huang, Lulu;
Ke, Yong;
Paerhati, Pameila;
Zhang, Jiawei;
Zong, Huifang;
Zhang, Baohong;
Zhu, Jianwei

Publication type:

Article

TRYPSIN AND CHYMOTRYPSIN ACTIVITY IN DEVELOPMENTAL STAGES OF ACANTHOSCELIDES OBTECTUS (SAY) AND SCREENING PHASEOLUS VULGARIS CULTIVARS FOR INHIBITORY EFFECT ON BOVINE PANCREATIC PROTEASES.

Published in:

Indian Journal of Entomology, 2025, v. 87, n. 3, p. 1, doi. 10.55446/IJE.2024.2413

By:

AZAD, RAJESH KUMAR;
THAKUR, DESH RAJ

Publication type:

Article

De novo designed protein guiding targeted protein degradation.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-62050-z

By:

Li, Zhendong;
Qiao, Gan;
Wang, Xianghe;
Wang, Ming;
Cheng, Jinyu;
Hu, Guipeng;
Li, Xiaomin;
Wu, Jing;
Liu, Jia;
Gao, Cong;
Liu, Liming

Publication type:

Article

АЛМАТЫ ОБЛЫСЫНЫҢ ЕКІ ЫСТЫҚ БҰЛАҚ КӨЗІНДЕГІ КЕРАТИНАЗАЛЫҚ БЕЛСЕНДІЛІГІ БАР ТЕРМОФИЛЬДІ БАКТЕРИЯЛАРДЫҢ СИПАТТАМАСЫ.

Published in:

Experimental Biology (1563-0218), 2025, v. 102, n. 1, p. 128, doi. 10.26577/bb2025102111

By:

Бисенова, Ұ. М.;
Кистаубаева, А. С.;
Абдулжанова, М. А.

Publication type:

Article

Nrf2/UBE3B protects against acute lung injury by inhibiting ferritinophagy through the ubiquitination of NCOA4.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00678-z

By:

Gu, Yunfan;
Dong, Hui;
Wang, Yanjun;
Hu, Beibei;
Jiang, Hong;
Hu, Rong

Publication type:

Article

Role of laccase and xylanase, with or without ferulic acid esterase-producing Lactiplantibacillus plantarum, on the aerobic stability, microbial composition and in vitro degradability of mulberry silage.

Published in:

BMC Microbiology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12866-025-04165-3

By:

Su, Ya;
Yu, Qiang;
Xi, Yulong;
Rong, Yuanjiang;
Long, Yixi;
Xie, Yixiao;
Sun, Hong;
Hao, Jun;
Yang, Fuyu;
Zheng, Yulong

Publication type:

Article

Effects Of Carbaryl Exposure On The Protein Content Of Cyprinus Carpio.

Published in:

Cuestiones de Fisioterapia, 2025, v. 54, n. 4, p. 5545

By:

Arumugam, M.;
Prabakaran, Victor

Publication type:

Article

Mechanistic insights into PROTAC-mediated degradation through an integrated framework of molecular dynamics, free energy landscapes, and quantum mechanics: A case study on kinase degraders.

Published in:

Journal of Computer-Aided Molecular Design, 2025, v. 39, n. 1, p. 1, doi. 10.1007/s10822-025-00630-3

By:

Nandy, Ashis;
Boppana, Kiran;
Phukan, Samiron

Publication type:

Article

Identification of host cell surface proteins inhibiting furin dependent proteolytic processing of viral glycoproteins.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-11164-x

By:

Williams, Nathalia;
Chabert, Mehdi;
Besomi, Alicia;
Silva, Filo;
Sobiech, Karolina;
Schmolke, Mirco

Publication type:

Article

Methods to accelerate PROTAC drug discovery.

Published in:

Biochemical Journal, 2025, v. 482, n. 13, p. 921, doi. 10.1042/BCJ20243018

By:

Osman, Jeyan;
Thompson, Philip E.;
Jörg, Manuela;
Scanlon, Martin J.

Publication type:

Article

Developing a Functional Triticale Noodle by Incorporating Silkworm (Antheraea pernyi and Bombyx mori) Pupae.

Published in:

Foods, 2025, v. 14, n. 13, p. 2282, doi. 10.3390/foods14132282

By:

Liu, Yu;
Liu, Ruixin;
Phuseerit, Onanong;
Li, Hua;
Siriamornpun, Sirithon

Publication type:

Article

The Potential of Combining Faba Bean (Vicia faba L.) and Pea Pod (Pisum sativum L.) Flours to Enhance the Nutritional Qualities of Food Products.

Published in:

Foods, 2025, v. 14, n. 13, p. 2167, doi. 10.3390/foods14132167

By:

Ben Said, Khaoula;
Hedhili, Amel;
Bellagha, Sihem;
Gliguem, Hela;
Dufrechou, Marie

Publication type:

Article

The Identification of Proteolytic Substrates of Calpain-5 with N-Terminomics.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6459, doi. 10.3390/ijms26136459

By:

Gal, Jozsef;
Dufour, Antoine;
Young, Daniel;
Yang, Eddy S.;
Geddes, James W.

Publication type:

Article

Effectiveness of PROTAC BET Degraders in Combating Cisplatin Resistance in Head and Neck Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6185, doi. 10.3390/ijms26136185

By:

Luffman, Natalie;
Ahmadinejad, Fereshteh;
Finnegan, Ryan M.;
Raymond, Marissa;
Gewirtz, David A.;
Harada, Hisashi

Publication type:

Article

Effects of Polypropylene and Polyethylene Terephthalate Microplastics on Trypsin Structure and Function.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 5974, doi. 10.3390/ijms26135974

By:

Lujic, Tamara;
Gligorijevic, Nikola;
Stanic-Vucinic, Dragana;
Krstic Ristivojevic, Maja;
Mutic, Tamara;
Wimmer, Lukas;
Dailey, Lea Ann;
Cirkovic Velickovic, Tanja

Publication type:

Article

Pembrolizumab promotes degradation of cyclin dependent kinase 6 and suppresses ovarian cancer progression in vitro.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-11043-5

By:

Wu, Yi;
Xu, Ziyan;
Kou, Zuqiang;
Ye, Qiuling;
Chen, Liting;
Gou, Boyu

Publication type:

Article

The Role of Protein Ubiquitination in the Onset and Progression of Sepsis.

Published in:

Cells (2073-4409), 2025, v. 14, n. 13, p. 1012, doi. 10.3390/cells14131012

By:

Chen, Meng-Yan;
Liu, Yang;
Fang, Min

Publication type:

Article

"Unraveling EMILIN-1: A Multifunctional ECM Protein with Tumor-Suppressive Roles" Mechanistic Insights into Cancer Protection Through Signaling Modulation and Lymphangiogenesis Control.

Published in:

Cells (2073-4409), 2025, v. 14, n. 13, p. 946, doi. 10.3390/cells14130946

By:

Muzzin, Samanta;
Timis, Enrica;
Doliana, Roberto;
Mongiat, Maurizio;
Spessotto, Paola

Publication type:

Article

The Ac/N-Degron Domain of MARCHF6 E3 Ubiquitin Ligase and Its Role in Regulating Ferroptosis.

Published in:

Cells (2073-4409), 2025, v. 14, n. 13, p. 954, doi. 10.3390/cells14130954

By:

Omoniyi, Hope;
Hohman, Grace;
Eldeeb, Mohamed

Publication type:

Article

Multi-path direct current spinal stimulation extended survival in the SOD1-G93A model of amyotrophic lateral sclerosis.

Published in:

Frontiers in Neurology, 2025, p. 1, doi. 10.3389/fneur.2025.1594169

By:

Ahmed, Zaghloul;
Samaddar, Sreyashi;
Hassieb, May;
Sadek, Rodina;
Morozova, Viktoriya;
Begum, Sultana

Publication type:

Article

Nuclear p62/SQSTM1 facilitates ubiquitin-independent proteasomal degradation of BMAL1.

Published in:

PLoS Genetics, 2025, v. 21, n. 7, p. 1, doi. 10.1371/journal.pgen.1011794

By:

Zhang, Chenliang;
Wu, Quanyou;
Zhang, Huan;
Liu, RuiChen;
Li, Liping

Publication type:

Article

Mechanisms of skeletal muscle atrophy in type 2 diabetes mellitus.

Published in:

Frontiers in Physiology, 2025, p. 1, doi. 10.3389/fphys.2025.1607873

By:

Yang, Jingyi;
Wang, Yingdong;
Xu, Yuzhe;
Jia, Xinqi;
Lu, Fangping

Publication type:

Article

Integrative Multi-Omics Analysis and Experimental Validation Identify SPOP as a Prognostic Biomarker and Immune Regulator in Lung Adenocarcinoma.

Published in:

Journal of Cancer, 2025, v. 16, n. 9, p. 2984, doi. 10.7150/jca.111751

By:

Yu Wang;
Tao Jiang;
Ziyou Lin;
Peijun Dai;
Wenxin Wei;
Chengyuan Dong;
Xuelin Zhang;
Zhifeng Zhang

Publication type:

Article

Unveiling New Triazoloquinoxaline‐Based PROTACs Designed for the Selective Degradation of the ncBAF Chromatin Remodeling Subunit BRD9.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 34, p. 1, doi. 10.1002/chem.202404218

By:

Pierri, Martina;
Bove, Guglielmo;
Gazzillo, Erica;
Colarusso, Ester;
Scala, Francesca;
Pepe, Giacomo;
Terracciano, Stefania;
Chini, Maria Giovanna;
Simonelli, Nicla;
Bruno, Ines;
Nebbioso, Angela;
Campiglia, Pietro;
Bifulco, Giuseppe;
Altucci, Lucia;
Del Gaudio, Nunzio;
Lauro, Gianluigi

Publication type:

Article

Nanoparticle‐Mediated Targeted Protein Degradation: An Emerging Therapeutics Technology.

Published in:

Angewandte Chemie, 2025, v. 137, n. 28, p. 1, doi. 10.1002/ange.202503958

By:

Baker, Andrew G.;
Ho, Adrian Pui Ting;
Itzhaki, Laura S.;
Fruk, Ljiljana

Publication type:

Article

Nutrients, Bioactive Compounds, and Antioxidant Activities of Garden Cress (Lepidium sativum L.) Seeds and Their Applications in Food Technology and Therapeutic Nutrition.

Published in:

Alexandria Science Exchange Journal, 2025, v. 46, n. 2, p. 263, doi. 10.21608/asejaiqjsae.2025.423922

By:

Ibrahim, Marwa E.;
Elhassaneen, Yousif A.;
Abd El-Aziz, Amany A.

Publication type:

Article

Targeted protein degradation by KLHDC2 ligands identified by high-throughput screening.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.106844

By:

Han Zhou;
Tonglian Zhou;
Wenli Yu;
Liping Liu;
Yeonjin Ko;
Johnson, Kristen A.;
Wilson, Ian A.;
Schultz, Peter G.;
Bollong, Michael J.

Publication type:

Article

Sensl: a synthetic biology sensor for tracking strigolactone signaling in rice.

Published in:

New Phytologist, 2025, v. 247, n. 3, p. 1031, doi. 10.1111/nph.70242

By:

Li, Yirou;
Wang, Fei;
Du, Ran;
Xie, Daoxin;
Yan, Jianbin;
Shan, Xiaoyi

Publication type:

Article

SE(3)-equivariant ternary complex prediction towards target protein degradation.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61272-5

By:

Xue, Fanglei;
Zhang, Meihan;
Li, Shuqi;
Gao, Xinyu;
Wohlschlegel, James A.;
Huang, Wenbing;
Yang, Yi;
Deng, Weixian

Publication type:

Article

In situ construction of intracellular supramolecular assemblies as an alternative strategy for protein degradation.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61175-5

By:

Hu, Xiaoqian;
Yao, Qingxin;
Wu, Xiaobo;
Chen, Jiali;
Zhang, Ruijia;
Zhao, Yan;
Gao, Yuan

Publication type:

Article