Works matching DE "SUBTILISINS"

Results: 535

Estimating the best PCSK9 vaccine design for atherosclerosis based on mouse models: A frequentist network meta-analysis.

Published in:

Global Cardiology Science & Practice, 2025, v. 2025, n. 2, p. 1, doi. 10.21542/gcsp.2025.19

By:

Iqhrammullah, Muhammad;
Muzaffar, Asyraf;
Homenta Rampengan, Derren David Christian;
Ichwan, Chairul;
Kalaij, Ayers Gilberth Ivano;
Al-Gunaid, Seba Talat;
Purba, Nur Adiba;
Gusti, Naufal;
Sufri, Muhammad Rinaldi;
Purnawarman, Adi

Publication type:

Article

Parasite biology: A perfectly timed escape.

Published in:

Nature Reviews Microbiology, 2015, v. 13, n. 12, p. 738, doi. 10.1038/nrmicro3586

By:

Waldron, Denise

Publication type:

Article

Genes Encoding Proteolytic Enzymes Fungalysin and Subtilisin in Dermatophytes of Human and Animal Origin: A Comparative Study.

Published in:

Mycopathologia, 2020, v. 185, n. 1, p. 137, doi. 10.1007/s11046-019-00367-2

By:

Kaplan, Engin;
Gonca, Serpil;
Kandemir, Hazal;
Döğen, Aylin;
Hilmioğlu-Polat, Süleyha;
Ilkit, Macit;
Tanaka, Reiko;
Yaguchi, Takashi;
Uhrlaβ, Silke;
Nenoff, Pietro

Publication type:

Article

Characterization and mutation analysis of a halotolerant serine protease from a new isolate of <italic>Bacillus subtilis</italic>.

Published in:

Biotechnology Letters, 2018, v. 40, n. 1, p. 189, doi. 10.1007/s10529-017-2459-2

By:

Takenaka, Shinji;
Yoshinami, Jyun;
Kuntiya, Ampin;
Techapun, Charin;
Leksawasdi, Noppol;
Seesuriyachan, Phisit;
Chaiyaso, Thanongsak;
Watanabe, Masanori;
Tanaka, Kosei;
Yoshida, Ken-ichi

Publication type:

Article

Salt hydrates for in situ water activity control have acidbase effects on enzymes in nonaqueous media.

Published in:

Biotechnology & Bioengineering, 2003, v. 82, n. 7, p. 802, doi. 10.1002/bit.10627

By:

Nuno Fontes;
Neil Harper;
Peter J. Halling;
Susana Barreiros

Publication type:

Article

Effect of ultrasound pretreatment and sequential hydrolysis on the production of Tenebrio molitor antidiabetic peptides.

Published in:

Food & Bioproducts Processing: Transactions of the Institution of Chemical Engineers Part C, 2020, v. 123, p. 217, doi. 10.1016/j.fbp.2020.07.003

By:

Rivero-Pino, Fernando;
Espejo-Carpio, F. Javier;
Pérez-Gálvez, Raúl;
Guadix, Antonio;
Guadix, Emilia M.

Publication type:

Article

Nattokinase: production and application.

Published in:

Applied Microbiology & Biotechnology, 2014, v. 98, n. 22, p. 9199, doi. 10.1007/s00253-014-6135-3

By:

Dabbagh, Fatemeh;
Negahdaripour, Manica;
Berenjian, Aydin;
Behfar, Abdolazim;
Mohammadi, Fatemeh;
Zamani, Mozhdeh;
Irajie, Cambyz;
Ghasemi, Younes

Publication type:

Article

Surface charge engineering of a Bacillus gibsonii subtilisin protease.

Published in:

Applied Microbiology & Biotechnology, 2013, v. 97, n. 15, p. 6793, doi. 10.1007/s00253-012-4560-8

By:

Jakob, Felix;
Martinez, Ronny;
Mandawe, John;
Hellmuth, Hendrik;
Siegert, Petra;
Maurer, Karl-Heinz;
Schwaneberg, Ulrich

Publication type:

Article

Biochemical features of microbial keratinases and their production and applications.

Published in:

Applied Microbiology & Biotechnology, 2010, v. 85, n. 6, p. 1735, doi. 10.1007/s00253-009-2398-5

By:

Brandelli, Adriano;
Daroit, Daniel J.;
Riffel, Alessandro

Publication type:

Article

Alkaliphilic Bacillus sp. strain KSM-LD1 contains a record number of subtilisin-like serine proteases genes.

Published in:

Applied Microbiology & Biotechnology, 2007, v. 76, n. 2, p. 395, doi. 10.1007/s00253-007-1022-9

By:

Takimura, Yasushi;
Saito, Kazuhiro;
Okuda, Mitsuyoshi;
Kageyama, Yasushi;
Saeki, Katsuhisa;
Ozaki, Katsuya;
Ito, Susumu;
Kobayashi, Tohru

Publication type:

Article

Functional identification of the gene bace16 from nematophagous bacterium Bacillus nematocida.

Published in:

Applied Microbiology & Biotechnology, 2007, v. 75, n. 1, p. 141, doi. 10.1007/s00253-006-0794-7

By:

Qiuhong Niu;
Xiaowei Huang;
Lin Zhang;
Lihui Lian;
Yunxia Li;
Juan Li;
Jinkui Yang;
Keqin Zhang

Publication type:

Article

A new approach for alteration of protease functions: pro-sequence engineering.

Published in:

Applied Microbiology & Biotechnology, 2003, v. 63, n. 1, p. 1, doi. 10.1007/s00253-003-1352-1

By:

Takagi, H.;
Takahashi, M.

Publication type:

Article

N-Glycosylation controls trafficking, zymogen activation and substrate processing of proprotein convertases PC1/3 and subtilisin kexin isozyme-1.

Published in:

Glycobiology, 2011, v. 21, n. 10, p. 1290, doi. 10.1093/glycob/cwr060

By:

Zandberg, Wesley F;
Benjannet, Suzanne;
Hamelin, Josée;
Pinto, B Mario;
Seidah, Nabil G

Publication type:

Article

Association between plasma PCSK9 levels and lipid profile in patients with Parkinson's disease and comparison with healthy subjects.

Published in:

Current Journal of Neurology, 2022, v. 21, n. 4, p. 236, doi. 10.18502/cjn.v21i4.11721

By:

Jahed, Mohammad Reza;
Habibi, Seyed Amir Hassan;
Vaseghi, Golnaz;
Amiri, Hasan;
Montazeri, Hamed;
Eshragh, Azedeh

Publication type:

Article

CylA is a sequence-specific protease involved in toxin biosynthesis.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2019, v. 46, n. 3/4, p. 537, doi. 10.1007/s10295-018-2110-9

By:

Tang, Weixin;
Bobeica, Silvia C.;
Wang, Li;
van der Donk, Wilfred A.

Publication type:

Article

PCSK9 Inhibitors "Fast Track" Use Versus "Stepwise" Lipid-Lowering Therapy in Patients with Acute Coronary Syndrome: A Retrospective Single-Center Study in a "Real-World" Population.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 9, p. 2992, doi. 10.3390/jcm14092992

By:

D'Andrea, Davide;
Capone, Valentina;
Bellis, Alessandro;
Castaldo, Rossana;
Franzese, Monica;
Carpinella, Gerardo;
Furbatto, Fulvio;
La Rocca, Fulvio;
Marsico, Fabio;
Marfella, Raffaele;
Paolisso, Giuseppe;
Paolisso, Pasquale;
Fumagalli, Carlo;
Cappiello, Maurizio;
Bossone, Eduardo;
Mauro, Ciro

Publication type:

Article

Correction: van Veelen et al. First-in-Human Drug-Eluting Balloon Treatment of Vulnerable Lipid-Rich Plaques: Rationale and Design of the DEBuT-LRP Study. J. Clin. Med. 2023, 12 , 5807.

Published in:

2024

By:

van Veelen, Anna;
Küçük, I. Tarik;
Fuentes, Federico H.;
Kahsay, Yirga;
Garcia-Garcia, Hector M.;
Delewi, Ronak;
Beijk, Marcel A. M.;
den Hartog, Alexander W.;
Grundeken, Maik J.;
Vis, M. Marije;
Henriques, José P. S.;
Claessen, Bimmer E. P. M.

Publication type:

Correction Notice

Management of High-Risk Hypercholesterolemic Patients and PCSK9 Inhibitors Reimbursement Policies: Data from a Cohort of Italian Hypercholesterolemic Outpatients.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 16, p. 4701, doi. 10.3390/jcm11164701

By:

Fogacci, Federica;
Giovannini, Marina;
Grandi, Elisa;
Imbalzano, Egidio;
Degli Esposti, Daniela;
Borghi, Claudio;
Cicero, Arrigo F. G.

Publication type:

Article

Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors Use for Atherogenic Dyslipidemia in Solid Organ Transplant Patients.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 11, p. 3247, doi. 10.3390/jcm11113247

By:

Cuomo, Gianluigi;
Cioffi, Giuseppe;
Di Lorenzo, Anna;
Iannone, Francesca Paola;
Cudemo, Giuseppe;
Iannicelli, Anna Maria;
Pacileo, Mario;
D'Andrea, Antonello;
Vigorito, Carlo;
Iannuzzo, Gabriella;
Giallauria, Francesco

Publication type:

Article

Rapid Decline of Serum Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) in Non-Cirrhotic Patients with Chronic Hepatitis C Infection Receiving Direct-Acting Antiviral Therapy.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 8, p. 1621, doi. 10.3390/jcm10081621

By:

Grimm, Jonathan;
Peschel, Georg;
Müller, Martina;
Schacherer, Doris;
Wiest, Reiner;
Weigand, Kilian;
Buechler, Christa

Publication type:

Article

Inhibitors of Protein Convertase Subtilisin/Kexin 9 (PCSK9) and Acute Coronary Syndrome (ACS): The State-of-the-Art.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 7, p. 1510, doi. 10.3390/jcm10071510

By:

Iannuzzo, Gabriella;
Gentile, Marco;
Bresciani, Alessandro;
Mallardo, Vania;
Di Lorenzo, Anna;
Merone, Pasquale;
Cuomo, Gianluigi;
Pacileo, Mario;
Sarullo, Filippo M.;
Venturini, Elio;
D'Andrea, Antonello;
Vigorito, Carlo;
Giallauria, Francesco;
Kubica, Jacek

Publication type:

Article

Methotrexate Decreases the Level of PCSK9—A Novel Indicator of the Risk of Proatherogenic Lipid Profile in Psoriasis. The Preliminary Data.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 4, p. 910, doi. 10.3390/jcm9040910

By:

Krahel, Julita Anna;
Baran, Anna;
Kamiński, Tomasz W.;
Maciaszek, Magdalena;
Flisiak, Iwona

Publication type:

Article

Circulating PCSK9 Level and Risk of Cardiovascular Events and Death in Hemodialysis Patients.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 1, p. 244, doi. 10.3390/jcm9010244

By:

Hwang, Hyeon Seok;
Kim, Jin Sug;
Kim, Yang Gyun;
Lee, So-Young;
Ahn, Shin Young;
Lee, Hong Joo;
Lee, Dong-Young;
Lee, Sang Ho;
Moon, Ju Young;
Jeong, Kyung Hwan

Publication type:

Article

Cost–Utility Analysis of PCSK9 Inhibitors and Quality of Life: A Two-Year Multicenter Non-Randomized Study.

Published in:

Diseases, 2024, v. 12, n. 10, p. 244, doi. 10.3390/diseases12100244

By:

Seijas-Amigo, José;
Mauriz-Montero, Maria José;
Suarez-Artime, Pedro;
Gayoso-Rey, Mónica;
Reyes-Santías, Francisco;
Estany-Gestal, Ana;
Casas-Martínez, Antonia;
González-Freire, Lara;
Rodriguez-Vazquez, Ana;
Pérez-Rodriguez, Natalia;
Villaverde-Piñeiro, Laura;
Castro-Rubinos, Concepción;
Espino-Paisán, Esther;
Cordova-Arevalo, Octavio;
Rodriguez-Penas, Diego;
Cardeso-Paredes, Begoña;
Ribeiro-Ferreiro, Marta;
Rodríguez-Mañero, Moisés;
Cordero, Alberto;
González-Juanatey, José R.

Publication type:

Article

The Role of Lipid-Lowering Treatment in the Secondary Prevention of Ischemic Stroke.

Published in:

Diseases, 2022, v. 10, n. 1, p. 3, doi. 10.3390/diseases10010003

By:

Tsankof, Alexandra;
Tziomalos, Konstantinos

Publication type:

Article

Inclisiran: A New Promising Agent in the Management of Hypercholesterolemia.

Published in:

Diseases, 2018, v. 6, n. 3, p. 63, doi. 10.3390/diseases6030063

By:

Kosmas, Constantine E.;
Muñoz Estrella, Alba;
Sourlas, Andreas;
Silverio, Delia;
Hilario, Elizabeth;
Montan, Peter D.;
Guzman, Eliscer;
Bakillah, Ahmed

Publication type:

Article

Advancement in nanotechnology-based approaches for the treatment and diagnosis of hypercholesterolemia.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2018, v. 46, p. 188, doi. 10.1080/21691401.2017.1417863

By:

Gupta, Nidhi;
Sharma, Nikita;
Mathur, Sandeep K.;
Chandra, Ramesh;
Nimesh, Surendra

Publication type:

Article

Subtilisin-like proteases in plant--pathogen recognition and immune priming: a perspective.

Published in:

Frontiers in Plant Science, 2014, v. 5, p. 1, doi. 10.3389/fpls.2014.00739

By:

Figueiredo, Andreia;
Monteiro, Filipa;
Sebastiana, Mónica

Publication type:

Article

PCSK9 Variants in Familial Hypercholesterolemia: A Comprehensive Synopsis.

Published in:

Frontiers in Genetics, 2020, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.01020

By:

Guo, Qianyun;
Feng, Xunxun;
Zhou, Yujie

Publication type:

Article

Effect of alirocumab on postprandial hyperlipidaemia in patients with type 2 diabetes: A randomized, double‐blind, placebo‐controlled, cross‐over trial.

Published in:

Diabetes, Obesity & Metabolism, 2025, v. 27, n. 6, p. 3006, doi. 10.1111/dom.16305

By:

Cariou, Bertrand;
Thys, An;
Oliveira, Arsênio Rodrigues;
Letertre, Marine P. M.;
Guyomarch, Béatrice;
Carpentier, Maxime;
Cannet, Claire;
Morcel, Pierre;
Ernould, Audrey;
Flet, Laurent;
Giraudeau, Patrick;
Hadjadj, Samy;
Le May, Cédric;
Croyal, Mikaël

Publication type:

Article

PCSK9 inhibitor therapy: A systematic review and meta‐analysis of metabolic and cardiovascular outcomes in patients with diabetes.

Published in:

Diabetes, Obesity & Metabolism, 2019, v. 21, n. 4, p. 903, doi. 10.1111/dom.13599

By:

Monami, Matteo;
Sesti, Giorgio;
Mannucci, Edoardo

Publication type:

Article

Efficacy and safety of proprotein convertase subtilisin/kexin 9 inhibitors in people with diabetes and dyslipidaemia.

Published in:

Diabetes, Obesity & Metabolism, 2019, v. 21, p. 39, doi. 10.1111/dom.13636

By:

Dijk, Wieneke;
Cariou, Bertrand

Publication type:

Article

Effect of proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies on new‐onset diabetes mellitus and glucose metabolism: A systematic review and meta‐analysis.

Published in:

Diabetes, Obesity & Metabolism, 2018, v. 20, n. 6, p. 1391, doi. 10.1111/dom.13235

By:

Cao, Ye‐Xuan;
Liu, Hui‐Hui;
Dong, Qiu‐Ting;
Li, Sha;
Li, Jian‐Jun

Publication type:

Article

Glycaemic control influences the relationship between plasma PCSK9 and LDL cholesterol in type 1 diabetes.

Published in:

Diabetes, Obesity & Metabolism, 2017, v. 19, n. 3, p. 448, doi. 10.1111/dom.12819

By:

Laugier‐Robiolle, Stéphanie;
Vergès, Bruno;
Le Bras, Maëlle;
Gand, Elise;
Bouillet, Benjamin;
Saulnier, Pierre‐Jean;
Le May, Cédric;
Pichelin, Matthieu;
Maréchaud, Richard;
Petit, Jean‐Michel;
Hadjadj, Samy;
Cariou, Bertrand

Publication type:

Article

Effect of statin therapy on plasma proprotein convertase subtilisin kexin 9 ( PCSK9) concentrations: a systematic review and meta-analysis of clinical trials.

Published in:

Diabetes, Obesity & Metabolism, 2015, v. 17, n. 11, p. 1042, doi. 10.1111/dom.12536

By:

Sahebkar, A.;
Simental‐Mendía, L. E.;
Guerrero‐Romero, F.;
Golledge, J.;
Watts, G. F.

Publication type:

Article

Fenofibrate concomitantly decreases serum proprotein convertase subtilisin/kexin type 9 and very-low-density lipoprotein particle concentrations in statin-treated type 2 diabetic patients.

Published in:

Diabetes, Obesity & Metabolism, 2010, v. 12, n. 9, p. 752, doi. 10.1111/j.1463-1326.2010.01229.x

By:

Chan, D. C.;
Hamilton, S. J.;
Rye, K. A.;
Chew, G. T.;
Jenkins, A. J.;
Lambert, G.;
Watts, G. F.

Publication type:

Article

Using Human 'Experiments of Nature' to Predict Drug Safety Issues: An Example with PCSK9 Inhibitors.

Published in:

2018

By:

Jerome, Rebecca N.;
Pulley, Jill M.;
Roden, Dan M.;
Shirey-Rice, Jana K.;
Bastarache, Lisa A.;
R. Bernard, Gordon;
B. Ekstrom, Leeland;
Lancaster, William J.;
Denny, Joshua C.

Publication type:

journal article

The Effect of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors on Nonfasting Remnant Cholesterol in a Real World Population.

Published in:

Journal of Lipids, 2018, p. 1, doi. 10.1155/2018/9194736

By:

Morise, Anthony P.;
Tennant, Jennifer;
Holmes, Sari D.;
Tacker, Danyel H.

Publication type:

Article

Treadmill Exercise Training Modulates Hepatic Cholesterol Metabolism and Circulating PCSK9 Concentration in High-Fat-Fed Mice.

Published in:

Journal of Lipids, 2013, p. 1, doi. 10.1155/2013/908048

By:

Shin Wen;
Jadhav, Kavita S.;
Williamson, David L.;
Rideout, Todd C.

Publication type:

Article

MicroRNA-338-3p regulates age-associated osteoporosis via targeting PCSK5.

Published in:

Molecular Medicine Reports, 2021, v. 23, n. 2, p. N.PAG

By:

Tong, Jie;
Zhang, Min;
Li, Xia;
Ren, Guohai

Publication type:

Article

Quercetin protects against ox-LDL-induced injury via regulation of ABCAl, LXR-α and PCSK9 in RAW264.7 macrophages.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 1, p. 799, doi. 10.3892/mmr.2018.9048

By:

Li, Shanshan;
Cao, Hui;
Shen, Dingzhu;
Jia, Qingling;
Chen, Chuan;
Xing, San Li

Publication type:

Article

Investigation of highly expressed PCSK9 in atherosclerotic plaques and ox-LDL-induced endothelial cell apoptosis.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 2, p. 1817, doi. 10.3892/mmr.2017.6803

By:

JIAO LI;
XUE LIANG;
YUANYUAN WANG;
ZHAO XU;
GUANGPING LI

Publication type:

Article

Inhibition of pro-protein convertase subtilisin/kexin type 6 has a protective role against synovitis in a rat model of rheumatoid arthritis.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 5, p. 7681, doi. 10.3892/mmr.2015.4376

By:

HUIYU JIANG;
LIN WANG;
JIHONG PAN

Publication type:

Article

Plasma Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) as a Possible Biomarker for Severe COVID-19.

Published in:

Viruses (1999-4915), 2023, v. 15, n. 7, p. 1511, doi. 10.3390/v15071511

By:

Mester, Patricia;
Amend, Pablo;
Schmid, Stephan;
Müller, Martina;
Buechler, Christa;
Pavel, Vlad

Publication type:

Article

Does BCA3 Play a Role in the HIV-1 Replication Cycle?

Published in:

Viruses (1999-4915), 2018, v. 10, n. 4, p. 212, doi. 10.3390/v10040212

By:

Rumlová, Michaela;
Křížová, Ivana;
Zelenka, Jaroslav;
Weber, Jan;
Ruml, Tomáš

Publication type:

Article

Management of hypercholesterolemia, appropriateness of therapeutic approaches and new drugs in patients with high cardiovascular risk.

Published in:

Italian Journal of Medicine, 2018, v. 12, n. 3, p. 203, doi. 10.4081/itjm.2018.1062

By:

Vettor, Roberto;
Serra, Roberto

Publication type:

Article

Proprotein convertase subtilisin/kexin type 9 genetic screening using the vervet (Chlorocebus aethiops) model.

Published in:

Journal of Medical Primatology, 2023, v. 52, n. 1, p. 45, doi. 10.1111/jmp.12623

By:

Ngqaneka, Thobile;
Obikeze, Kenechukwu;
Magwebu, Zandisiwe E.;
Chauke, Chesa G.

Publication type:

Article

Effects of 12 weeks of treatment with intravenously administered bococizumab, a humanized monoclonal antibody blocking proprotein convertase subtilisin/kexin type 9, in hypercholesterolemic subjects on high‐dose statin.

Published in:

Cardiovascular Therapeutics, 2018, v. 36, n. 1, p. 1, doi. 10.1111/1755-5922.12308

By:

Fazio, Sergio;
Robertson, David G.;
Joh, Tenshang;
Wan, Hong;
Riel, Tom;
Forgues, Philippe;
Baum, Charles M.;
Garzone, Pamela D.;
Gumbiner, Barry

Publication type:

Article

The effect of APOE, CETP, and PCSK9 polymorphisms on simvastatin response in Thai hypercholesterolemic patients.

Published in:

Cardiovascular Therapeutics, 2017, v. 35, n. 6, p. n/a, doi. 10.1111/1755-5922.12302

By:

Wanmasae, Smith;
Sirintronsopon, Wisant;
Porntadavity, Sureerut;
Jeenduang, Nutjaree

Publication type:

Article

An Update on the Clinical Development of Proprotein Convertase Subtilisin Kexin 9 Inhibitors, Novel Therapeutic Agents for Lowering Low-Density Lipoprotein Cholesterol.

Published in:

Cardiovascular Therapeutics, 2014, v. 32, n. 2, p. 82, doi. 10.1111/1755-5922.12056

By:

Ling, Hua;
Burns, Tammy L.;
Hilleman, Daniel E.

Publication type:

Article