Works matching DE "TUMOR microenvironment"

Results: 5000

Bioorthogonal Click‐to‐Release of Branched Pro‐Fluorophores.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 42, p. 1, doi. 10.1002/chem.202501544

By:

Brind, Thomasin;
Lawer, Aggie;
Todd, Tobias;
Aryal, Sushant;
Hook, Sarah;
Gamble, Allan B.

Publication type:

Article

Decoding NF-κB: nucleocytoplasmic shuttling dynamics, synthetic modulation and post-therapeutic behavior in cancer.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10917-1

By:

Alhallaq, Ahmed S.;
Sultan, Nadeen S.

Publication type:

Article

Connexin 43 inhibitors reduce cell viability in glioblastoma and astrocyte co-culture systems.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10902-8

By:

Genc, Ali;
Uzunkaya, Berfin;
Yengin, Gizem Inetas;
Tecimel, Didem;
Dalan, Altay Burak;
Bayrak, Omer Faruk

Publication type:

Article

OPPORTUNITIES AND CHALLENGES FOR TARGETING CANCER METABOLISM.

Published in:

Transactions of the American Clinical & Climatological Association, 2025, n. 135, p. 196

By:

DANG, CHI V.

Publication type:

Article

Multi-omics dissection of CPNE1 reveals its prognostic value and immune-regulatory function in liver cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03366-6

By:

Liu, Liu;
Hong, He;
Zhang, Weiwei;
Li, Xiang;
Yao, Yuan;
Zhang, Zhengjun;
Li, Guangyao

Publication type:

Article

Mapping thirty years of tumour-microenvironment-driven drug resistance in breast cancer: a global bibliometric analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03324-2

By:

Duan, Zuoping;
Zhou, Yonghong;
Wu, Yang

Publication type:

Article

Advanced diffusion-weighted imaging biomarkers for non-invasive assessment of tumor microenvironment in rectal cancer: restricted spectrum imaging.

Published in:

Abdominal Radiology, 2025, v. 50, n. 9, p. 3917, doi. 10.1007/s00261-025-04819-w

By:

Yuan, Jie;
Sun, Yiqun;
Liu, Kun;
Han, Gang;
Wang, Ziyuan;
Liu, Mengxiao;
Dai, Yongming;
Tang, Cui;
Wu, Dongmei

Publication type:

Article

Pan-cancer landscape of ITGAV and its potential role in gastric cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-14342-z

By:

Ke, Bin;
Jin, Peng;
Wang, Xue-Jun;
Zhang, Ru-peng;
Liu, Ning;
Ma, Gang

Publication type:

Article

Machine learning derived development and validation of extracellular matrix related signature for predicting prognosis in adolescents and young adults glioma.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-13547-6

By:

Wu, Pancheng;
Zheng, Yi;
Wu, Wei;
Zhang, Beichen;
Wang, Yichang;
Zhou, Mingjing;
Liu, Ziyi;
Wang, Zhao;
Wang, Maode;
Wang, Jia

Publication type:

Article

Sorafenib-treated Th9 cells exhibit superior anti-tumor effect in lung metastasis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-11450-8

By:

Yuan, Fanli;
Wang, Hanliang;
Wang, Shuowang;
Wang, Jin;
Li, Junwei;
Shen, Yingying;
Lin, Jianjun;
Guo, Jufeng;
Cai, Lingzhi

Publication type:

Article

Identification of SMYD2 as a candidate diagnostic and prognostic biomarker for gastric cancer.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1617971

By:

Wang, Sichao;
Zhao, Chuanxi;
Li, Dongmei;
Liu, Qingzhi;
Mao, Cuiping;
Ding, Shanshan;
Zhang, Shujun;
Shang, Wenjing

Publication type:

Article

Global research landscape of antiangiogenic therapy for colorectal cancer: a bibliometric analysis of mechanistic insights and clinical advancements.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1591059

By:

Hou, Ke-Qiang;
Wu, Jia-Ming;
Chen, Jie

Publication type:

Article

Transglutaminase 2 regulates ovarian cancer metastasis by modulating the immune microenvironment.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1639853

By:

Ibrahim, Dalia;
Grondin, Melanie;
Galpin, Kristianne;
Asif, Sara;
Thompson, Emily;
Nersesian, Sarah;
Abou-Hamad, John;
Echaibi, Maryam;
Rodriguez, Galaxia M.;
Navals, Pauline;
Macdonald, Elizabeth;
Ryan, Brianna;
Cook, David P.;
Keillor, Jeffrey W.;
Vanderhyden, Barbara C.

Publication type:

Article

Immunotherapy enhances the risk of tumor oxidative stress and metastasis in lung cancer with radiation pneumonitis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1629170

By:

Jiao, Ruidi;
Xu, Wenbo;
Xu, Kunpeng;
Zhang, Mingxia;
Liu, Weilong;
Jiang, Wei;
Wang, Luhua

Publication type:

Article

Alveolar macrophages maintain tissue localization and gain enhanced anti-tumor activity in Lewis lung carcinoma-reprogrammed lung microenvironment.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1616514

By:

Ren, Mengfei;
Dou, Jiaxiang;
Yue, Qian;
Ma, Liqin;
Yu, Hang;
Shang, Shengwen;
Wang, Shijie;
Wang, Jian;
Li, Tingting;
Li, Fengqi

Publication type:

Article

Cancer-specific senescence signature promotes malignant phenotypes and immunotherapy resistance in colorectal cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1603787

By:

Wang, Wei;
Ling, Fengyu;
Huang, Dong;
Luo, Guomin;
Duan, Bixia

Publication type:

Article

Pygo2+ T cells possess immunosuppressive features and inferior immunotherapeutic response in gastric cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1596434

By:

Chang, Weilong;
Yan, Huifang;
Zhang, Yawei;
Sang, Zibo;
Bu, Bei;
Deng, Rui;
Li, Kaibo;
Li, Jiajing;
Fu, Yang;
Cui, Jinyuan

Publication type:

Article

Immune analysis according to Lauren type for gastric cancer and its significance in individual treatment and prognostic prediction.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1589513

By:

Lu, Huiwen;
Yao, Junqiao;
Xue, Chi;
Huang, Rui;
Huang, Baojun

Publication type:

Article

Revolutionizing cervical cancer treatment: single-cell sequencing of TSPAN1+ tumor EPCs and immune checkpoints to assess drug sensitivity and optimize therapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1574174

By:

Li, Yumeng;
Lin, Zhiheng;
Lin, Guangyao;
Zhao, Zhijie;
Xiahou, Zhikai;
Cai, Pingping

Publication type:

Article

Identification of a coagulation-related classification and signature that predict disease heterogeneity for colorectal cancer and pan-cancer patients.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1572701

By:

Pei, Junpeng;
Gao, Yuye;
Xing, Baojian;
Chen, Yongjiu;
Wu, Aiwen

Publication type:

Article

Comprehensive review of the resistance mechanisms of colorectal cancer classified by therapy type.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1571731

By:

Oh, Janice M.;
Kim, Susan;
Tsung, Carolyn;
Kent, Eric;
Jain, Arad;
Ruff, Samantha M.;
Zhang, Hongji

Publication type:

Article

Interplay between tumor mutation burden and the tumor microenvironment predicts the prognosis of pan-cancer anti-PD-1/PD-L1 therapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1557461

By:

Liao, Wuyuan;
Zhou, Xinwei;
Lin, Hansen;
Feng, Zihao;
Chen, Xinyan;
Chen, Yuhang;
Chen, Minyu;
Lin, Mingjie;
Yao, Gaosheng;
Chen, Jinwei;
Feng, Haoqian;
Wang, Yinghan;
Tan, Zhiping;
Tan, Youyan;
Lu, Jun;
Li, Pengju;
Wei, Jinhuan;
Luo, Li;
Fu, Liangmin

Publication type:

Article

Calcium overload via PVT1 reprograms neutrophil fate and constrains gastric cancer progression.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06912-6

By:

Wang, Dong;
Li, Yunlong;
Peng, Xiaoyu;
Zhang, Lulu;
Zhang, Ying;
Guan, Xue;
Liang, Xiao;
Fu, Songbin;
Yu, Jingcui

Publication type:

Article

G protein-coupled receptors: pivotal hubs in gastric cancer malignancy—from multidimensional crosstalk to precision therapeutics.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06851-2

By:

Qin, Rong;
Fan, Xirui;
Huang, Yun;
Duan, Yiyao;
Wang, Hui

Publication type:

Article

Evaluating IL22RA1 expression as a predictive indicator in human colon cancer progression.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14715-7

By:

Yin, Xuan;
Geng, Renhao;
Chen, Junjun;
Xu, Bin;
Ma, Hui;
Liu, Yingting;
Zheng, Xiao;
Chen, Lujun

Publication type:

Article

A long-term glioblastoma survivor with Lynch syndrome: a case report of tumor molecular and microenvironment characterization.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03361-x

By:

Zhou, Yiqiang;
Duan, Qianqian;
Han, Tiantian;
Piao, Yueshan;
Tang, Jie

Publication type:

Article

Meta_B cells: a computationally identified candidate immunosuppressive driver of gastric cancer metastasis revealed by single-cell analysis and machine learning.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03356-8

By:

Lei, Tianchi;
Jiang, Yiwen;
Yang, Kexin;
Meng, Chuqi;
An, Yue

Publication type:

Article

The role of cellular heterogeneity in thyroid cancer: a multi-modal analysis approach with Mendelian randomization.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03348-8

By:

Qian, Yichun;
Chen, Wei;
Chen, Xinyuan;
Cheng, Shuai;
Liu, Fangzhou

Publication type:

Article

Recent advances in calcium peroxide nanomedicines for breast cancer treatment.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03329-x

By:

Hang, Sirui;
Xu, Liu;
Ma, Ruixue;
Xu, Huiqin;
Zhang, Xiaojuan;
He, Chuanchuan

Publication type:

Article

Collagen gene signature in the tumor microenvironment predicts survival and guides prognosis in bladder cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03136-4

By:

Huang, Yi;
Fang, Shuogui;
Xie, Weibin;
Zou, Yitong;
Zhuo, Hui;
Shen, Gang;
Zhou, Hua;
Mao, ChunPing;
Lai, Cong;
Kong, Jianqiu;
Fan, Xinxiang

Publication type:

Article

Stroma areactive invasion front areas (SARIFA) in 1,298 pT3/pT4 colorectal cancers: A strong prognostic parameter complementing established morphological criteria.

Published in:

Histopathology, 2025, v. 87, n. 3, p. 464, doi. 10.1111/his.15501

By:

Foersch, Sebastian;
Harb, Nuwar;
Litmeyer, Anne‐Sophie;
Roth, Wilfried;
Breus, Irina;
Schraml, Johannes;
Weiß, Annika;
Steiger, Katja;
Teply‐Szymanski, Julia;
Bartsch, Detlef K;
Denkert, Carsten;
Schmitt, Maxime;
Jesinghaus, Moritz

Publication type:

Article

Music therapy in modulating immune responses and enhancing cancer treatment outcomes.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1639047

By:

Fu, Ye;
Wu, Ke;
Zhuang, Jiajia;
Chen, Yisheng;
Jia, Lina;
Luo, Zhiwen;
Sun, Rong

Publication type:

Article

Immunosuppressive cells in acute myeloid leukemia: mechanisms and therapeutic target.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1627161

By:

Liu, Mengnan;
Yang, Mengting;
Qi, Yue;
Ma, Yuting;
Guo, Qulian;
Guo, Ling;
Liu, Chunyan;
Liu, Wenjun;
Xiao, Lan;
Yang, You

Publication type:

Article

Targeting CSC-immune cell crosstalk to overcome chemoresistance and enhance immunotherapy efficacy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1620807

By:

Yu, Guanxiao;
Gong, Jianbao

Publication type:

Article

Pygo2+ T cells possess immunosuppressive features and inferior immunotherapeutic response in gastric cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1596434

By:

Chang, Weilong;
Yan, Huifang;
Zhang, Yawei;
Sang, Zibo;
Bu, Bei;
Deng, Rui;
Li, Kaibo;
Li, Jiajing;
Fu, Yang;
Cui, Jinyuan

Publication type:

Article

Recent progress in the study of exosomes in the gastric cancer immune microenvironment.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1595124

By:

Liu, Haibo;
Zhu, Lei;
Yin, Jianmei

Publication type:

Article

WISP1 drives esophageal squamous cell carcinoma progression via modulation of cancer-associated fibroblasts and immune microenvironment.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1586790

By:

Yi, Zhiqiang;
Zhang, Qiqi;
Tao, Ting;
Liu, Xiaojia;
Li, Hui;
Li, Xiujuan;
Zhang, Zhiqiang

Publication type:

Article

Signalling pathways and cellular functions of KDEL receptors: implications in cancer biology.

Published in:

Cellular & Molecular Life Sciences, 2025, v. 82, n. 1, p. 1, doi. 10.1007/s00018-025-05820-8

By:

Dufrusine, Beatrice;
Cela, Ilaria;
Gramegna Tota, Chiara;
Palumbo, Marta;
Sallese, Michele

Publication type:

Article

Letter to editor: SIGMAR1 screened by a GPCR-related classifier regulates endoplasmic reticulum stress in bladder cancer.

Published in:

2025

By:

Zhang, Xiaoman;
Cong, Yipeng;
Zheng, Xu;
Wu, Guangzhen

Publication type:

Letter

An oral heme oxygenase inhibitor targets immunosuppressive perivascular macrophages in preclinical models of cancer.

Published in:

Science Translational Medicine, 2025, v. 17, n. 810, p. 1, doi. 10.1126/scitranslmed.ads3085

By:

Bahri, Meriem;
Al-Adhami, Taha;
Demirel, Emre;
Sarkar, Jit;
Feehan, Karen T.;
Anstee, Joanne E.;
Cheung, Tik Shing;
Sosnowska, Dominika;
Woodman, Chloé A.;
Macmorland, William;
Yang, Dorothy D.;
Rosekilly, James;
Gitsaki-Taylor, Renee;
Gillett, Cheryl E.;
Scudamore, Cheryl L.;
Spicer, James;
Rahman, Khondaker Miraz;
Arnold, James N.

Publication type:

Article

Unlocking the secret of glioblastoma multiforme: the role of lactylation in tumor progression, drug resistance and immune microenvironment.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03933-5

By:

Xiao, Yifei;
Zheng, Ruipeng;
Lv, Fengjun;
Yang, Guang;
Ge, Haitao;
Yang, Mingchun;
Wang, Kan;
Cheng, Yu

Publication type:

Article

Multi-omics profiling of metastatic colorectal cancer reveals the transcriptional network of focal adhesion and immune suppression and the role of p-RPS6.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03924-6

By:

Jiang, Yimei;
Li, Zhe;
Zheng, Fang;
Jia, Wenqing;
Guo, Zichao;
Xu, Zhuoqing;
Huang, Chenhao;
Li, Zhiliang;
Wang, Changgang;
Liu, Kun;
Feng, Haoran;
Zhao, Ren;
Cheng, Xi

Publication type:

Article

Investigating the potential role of miR-451a as a tumor suppressor in immunogenic cell death induction and dendritic cell maturation in colorectal cancer cell lines.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03919-3

By:

Azizi, Mahdieh;
Andalib, Alireza;
Rezaei, Marzieh

Publication type:

Article

Enhanced homing and efficacy of HER2-CAR T cells via CXCR5/CCR6 co-expression for HER2-positive NSCLC.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06866-9

By:

Hu, Xiaoyuan;
Ge, Chunlei;
Huang, Caixiu;
He, Dan;
Yao, Xiaoxuan;
Cheng, Jiaxing;
Guo, Jiyin;
Li, Ke;
Ye, Yunshan;
Li, Li;
Xia, Jianchuan;
Li, Tao;
Yao, Hong

Publication type:

Article

Distinct Lung Adenocarcinoma-Associated Microbiota Are Associated with Inflammatory Immune Landscapes and Tumor Cell Proliferation via LCIIAR–ISG15 Regulatory Networks.

Published in:

Cancer Management & Research, 2025, v. 17, p. 1315, doi. 10.2147/CMAR.S520098

By:

Liu, Shipu;
Zhang, Zijian

Publication type:

Article

Tumor-derived small extracellular vesicles reprogram sensory nerves to drive immunosuppression in the tumor microenvironment.

Published in:

Science Signaling, 2025, v. 18, n. 898, p. 1, doi. 10.1126/scisignal.ady6769

By:

Boyd, Leah;
Borniger, Jeremy C.

Publication type:

Article

A novel cuproptosis-related genes nomogram on the prognosis and immune microenvironment of breast invasive carcinoma.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-14621-9

By:

Shang, Guanmin;
Xu, Zhiwen;
Peng, Dengfu;
Liao, Xinghe;
Zhao, Jiangang

Publication type:

Article

Role of T cell exhaustion and tissue-resident memory T cells in the expression and prognosis of colorectal cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-14409-x

By:

Wu, Han;
Fan, Pei-Wen;
Feng, Ya-Ning;
Chang, Cheng;
Gui, Ting;
Meng, Jia-bei;
Wang, Ruo-Zheng

Publication type:

Article

Identification of novel molecular subtypes and construction of a prognostic signature via multi-omics analysis and machine learning in lung adenocarcinoma.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1590216

By:

Ma, Ke;
Xu, Jie;
Wang, Congyue;
Cao, Xu;
Yu, Wenjie;
Xi, Jingjing;
Zhang, Xuan;
Zhan, Jiamin;
Liu, Yang;
Yu, Aoyang;
Liu, Shuhan;
Liu, Yanhua;
Chen, Chong;
Mai, Xiaoli

Publication type:

Article

The protease-activated receptors are expressed in glioblastoma and differentially modulate adherent versus stem-like growth of LN-18 GBM cells.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1582996

By:

Bien-Möller, Sandra;
Grober, Antonia;
Albrecht, Judith;
Paland, Heiko;
Weitmann, Kerstin;
Bialke, Angela;
Marx, Sascha;
Vogelgesang, Silke;
Tzvetkov, Mladen V.;
Hoffmann, Wolfgang;
Schroeder, Henry W. S.;
Rauch, Bernhard H.

Publication type:

Article