Works matching DE "TUMOR microenvironment"

Results: 5000

Cathepsin L‐Activatable Fluorescent Probe for Real‐Time Monitoring of Drug‐Resistant Breast Cancer Cells.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 43, p. 1, doi. 10.1002/chem.202501624

By:

Yu, Qiqi;
Chen, Sina;
Yu, Liping;
Xu, Dongdong;
Yin, Shouchun

Publication type:

Article

The dual role of CD36 in cancer: from lipid metabolism to tumor microenvironment regulation.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10885-6

By:

Yao, Yixuan;
Fang, Yanyuan;
Yuan, Bin;
Yang, Jing

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Article

Peripheral nerves-cancer cross-talk: the next frontier in cancer treatment.

Published in:

Molecular & Cellular Biochemistry, 2025, v. 480, n. 8, p. 4533, doi. 10.1007/s11010-025-05256-5

By:

Wang, Leihan;
Qi, Teng;
Tang, Lingyun;
Wang, Yuehan;
ChenLiu, Zhenni;
Wang, Daorong;
Tang, Dong

Publication type:

Article

Development and validation of a hypoxia-immune-based microenvironment gene signature for predicting survival in non-small cell lung cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03319-z

By:

Zhang, Xiangwu;
Zhou, Rongxian;
Zhao, Guangqiang;
Chen, Wanling;
Zhao, Ping;
Huang, Yunchao;
Huang, Qiubo;
Ye, Lianhua

Publication type:

Article

Lysosome-derived biomarkers for predicting survival outcome in acute myeloid leukemia.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03302-8

By:

Li, Gongchang;
Miao, Yangyang;
Yuan, Fang;
Zhang, Weiran;
Wu, Yali;
Zhu, Liqiang

Publication type:

Article

Decoding tumor-infiltrating lymphocytes heterogeneity in ductal carcinoma in situ: immune microenvironment dynamics and prognostic insights.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03288-3

By:

Wang, Lingzi;
Yang, Yalong;
Song, Yuhang;
Zeng, Jiahui;
Zheng, Hongmei;
Wu, Xinhong

Publication type:

Article

Multimodal tumor microenvironment signature of colorectal cancer for prediction prognosis and chemotherapy benefit.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-01069-3

By:

Jiang, Wei;
Yang, Kun;
Xiao, Chanchan;
Ji, Hongli;
Yan, Botao;
Zhao, Shuhan;
Zhang, Biao;
Cheng, Jiaxin;
Xu, Shuoyu;
Wang, Guangxing;
Lin, Zexi;
Lu, Jianping;
Chen, Gang;
Zhuo, Shuangmu;
Yan, Jun

Publication type:

Article

Impact of HMGA1 on tumorigenesis, prognosis and immune microenvironment in HNSCC: a multi-omics study.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-01068-4

By:

Xu, Ziang;
Wang, Moxu;
Cai, Jilin;
Wang, Tianxiao;
Ni, Nan;
Liu, Tao;
Xue, Maojie;
Wang, Xiang;
Liu, Zhixuan;
Yuan, Hua;
Zhang, Wei;
Zhang, Ruyang

Publication type:

Article

Immune profiling of human vestibular schwannoma secretions identifies TNF-α and TWEAK as cytokines with synergistic potential to impair hearing.

Published in:

Journal of Neuroinflammation, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12974-025-03364-z

By:

Vasilijic, Sasa;
Seist, Richard;
Yin, Zhenzhen;
Xu, Lei;
Stankovic, Konstantina M.

Publication type:

Article

Promotion of the invasion and metastasis of breast cancer by B7-H3 through CCR5High tumor-associated macrophages.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03932-6

By:

Dai, Tiantian;
Xu, Zhihua;
Li, Yadi;
Wu, Mengni;
Qiu, Yue;
Chao, ZhuJun;
Jiang, Renhai;
Chen, Yan;
Lu, Linlin

Publication type:

Article

Analysis of the immune microenvironment in colorectal cancer with different KRAS gene subtypes.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14660-5

By:

Huang, Jing;
Gong, Qian;
Li, Qingshu;
Xiao, Ming;
Li, Ming;
Zhang, Shuxian;
Wang, Yalan;
Tang, Yi

Publication type:

Article

Metabolic checkpoints in immune cell reprogramming: rewiring immunometabolism for cancer therapy.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02407-6

By:

Lv, Yingying;
Li, Zongshang;
Liu, Shutong;
Zhou, Zhaokai;
Song, Jinling;
Ba, Yuhao;
Weng, Siyuan;
Zuo, Anning;
Xu, Hui;
Luo, Peng;
Cheng, Quan;
Zhang, Chuhan;
Ning, Jingyuan;
Chen, Yukang;
Zhang, Yuyuan;
Liu, Zaoqu;
Han, Xinwei

Publication type:

Article

Identification of prognostic genes related to T cell proliferation in papillary thyroid cancer based on single-cell RNA sequencing and bulk RNA sequencing data.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01826-5

By:

Meng, Qingkai;
Liu, Hongzhu;
Wang, Mengtong;
Jiang, Xin;
Wang, Yi;
Cao, Xiaoli;
Qu, Nina

Publication type:

Article

Identification of novel molecular subtypes and construction of a prognostic signature via multi-omics analysis and machine learning in lung adenocarcinoma.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1590216

By:

Ma, Ke;
Xu, Jie;
Wang, Congyue;
Cao, Xu;
Yu, Wenjie;
Xi, Jingjing;
Zhang, Xuan;
Zhan, Jiamin;
Liu, Yang;
Yu, Aoyang;
Liu, Shuhan;
Liu, Yanhua;
Chen, Chong;
Mai, Xiaoli

Publication type:

Article

JMJD8 overexpression in breast cancer: implications for diagnosis, prognosis, and immune microenvironment interactions.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1536278

By:

Zhu, Chenlei;
Xi, Tianyi;
Yang, Guorong;
Lu, Wen;
Wang, Sentai;
Cao, Jiwei

Publication type:

Article

Oncogenic CMTM6 drives M2a macrophages formation and fuels cervical cancer progression.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1621816

By:

Yin, Bo;
Chen, Chun;
Huang, Baoyou;
Ding, Jianyi;
Hu, Haoran;
Zhou, Huijuan;
Zhu, Yashi;
Huang, Tiefeng;
He, Xiang;
Lu, Yuan;
Han, Lingfei

Publication type:

Article

The pyroptosis-related gene signature predicts prognosis and reveals immune microenvironment infiltration in reclassified glioblastoma based on 2021 WHO classification.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1617036

By:

Zheng, Xiaohong;
Pan, Zhangchi;
Chen, Lina;
Wang, Can;
Li, Wenbin

Publication type:

Article

Unraveling NK cell heterogeneity through single-cell sequencing: insights from physiological and tumor contexts for clinical applications.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1612352

By:

Shen, Mingxin;
Liu, Yutong;
Shao, Liang;
Qu, Meng;
Song, Shixin;
Sun, Wei;
Zhang, Hao

Publication type:

Article

Integrated multi-omics analysis and machine learning identify G protein-coupled receptor-related signatures for diagnosis and clinical benefits in soft tissue sarcoma.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1561227

By:

Wang, Duo;
Tu, Jihao;
Liu, Jianfeng;
Piao, Yuting;
Zhao, Yiming;
Xiong, Ying;
Wang, Jianing;
Zheng, Xiaotian;
Liu, Bin

Publication type:

Article

Radiation therapy as a biological modifier of the breast cancer immune microenvironment.

Published in:

NPJ Breast Cancer, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41523-025-00801-3

By:

Galluzzi, Lorenzo;
Bolini, Lukas;
Shulman, Rebecca M.

Publication type:

Article

TIPE2 combined with immune cell infiltration predicts prognosis in colorectal cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10449-5

By:

Xia, Hengbo;
Pang, Qingqing;
Xu, Aman;
Hu, Jie

Publication type:

Article

Necroptosis in cancer: insight from epigenetic, post-transcriptional and post-translational modifications.

Published in:

Journal of Hematology & Oncology, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13045-025-01726-x

By:

Tang, Jinxin;
Zhuang, Yan;
Zhang, Yibo;
Hu, Hongkun;
Wang, Hua;
Xu, Haodong;
Li, Yintao;
Tu, Chao

Publication type:

Article

Sonodynamic biomimetic-nanomedicine fight cancers.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03583-9

By:

Zhang, Anni;
Zheng, Xu;
Yan, Guangqi;
Liu, Xiaoqi;
Xie, DongXuan;
Xu, Xiaohe;
Sun, Mengchi;
Liu, Zhijun

Publication type:

Article

The 10 commandments of immunoregulation in lymphoma.

Published in:

Science Immunology, 2025, v. 10, n. 109, p. N.PAG, doi. 10.1126/sciimmunol.aea0950

By:

de los Reyes Capilla Guerra, Maria;
Griffin, Gabriel K.

Publication type:

Article

Multimodal delineation of a layer of effector function among exhausted CD8 T cells in tumors.

Published in:

Science Immunology, 2025, v. 10, n. 109, p. 1, doi. 10.1126/sciimmunol.adt3537

By:

Ray, Arja;
Bassette, Molly;
Hu, Kenneth H.;
Pass, Lomax F.;
Courau, Tristan;
Samad, Bushra;
Combes, Alexis J.;
Johri, Vrinda;
Davidson, Brittany;
Wai, Katherine;
Ha, Patrick;
Hernandez, Grace;
Zaleta-Linares, Itzia;
Krummel, Matthew F.

Publication type:

Article

Noncanonical Hedgehog signaling through Smoothened controls cytotoxic T cell migration in the tumor microenvironment.

Published in:

Science Immunology, 2025, v. 10, n. 109, p. 1, doi. 10.1126/sciimmunol.adr3127

By:

Kapeni, Chrysa;
O'Brien, Louise;
Sabirova, Dilyara;
Cast, Oliver;
Carbonaro, Valentina;
Clark-Leonard, Stephen;
Machel, Anne C.;
Beke, Flavio;
McDonald, Sarah;
Fife, Kate;
de la Roche, Maike

Publication type:

Article

A lipid metabolism-related gene signature predicts prognosis after tamoxifen treatment in ER + breast cancer and reflects tumor microenvironment heterogeneity through single-cell analysis.

Published in:

BMC Medical Genomics, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s12920-025-02194-5

By:

Ma, Linxiaoxi;
Qian, Bei;
Peng, Chen;
Liu, Gang;
Shen, Hao

Publication type:

Article

Construction of an immune prediction model for osteosarcoma based on coagulation-related genes.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03214-7

By:

Jiang, Ye;
Yuan, Huiqi;
Cao, Yongping

Publication type:

Article

Biomimetic nanoparticles delivered hedgehog pathway inhibitor to modify tumour microenvironment and improved chemotherapy for pancreatic carcinoma.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2018, v. 46, p. 1088, doi. 10.1080/21691401.2018.1445093

By:

Jiang, Ting;
Zhang, Bo;
Zhang, Long;
Wu, Xuemei;
Li, Haichun;
Shen, Shun;
Luo, Zimiao;
Liu, Xianping;
Hu, Yu;
Pang, Zhiqing;
Jiang, Xinguo

Publication type:

Article

RNA sequencing and immunohistochemistry jointly improve tumor biomarker interpretation.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-12780-3

By:

Kushnarev, Vladimir;
Stupichev, Danil;
Davitavyan, Suren;
Kriukov, Kirill;
Shanthappa, Basavaraja U.;
Butusova, Anna;
Menshikova, Sofia;
Belozerova, Anna;
Shvyrkova, Anastasia;
Tkachuk, Arina;
Khatenkova, Olga;
Balabanian, Linda;
Postovalova, Ekaterina;
Lennerz, Jochen K.;
Meric-Bernstam, Funda;
Bagaev, Alexander

Publication type:

Article

TIPE2 combined with immune cell infiltration predicts prognosis in colorectal cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10449-5

By:

Xia, Hengbo;
Pang, Qingqing;
Xu, Aman;
Hu, Jie

Publication type:

Article

Identification of hub genes within the CCL18 signaling pathway in hepatocellular carcinoma through bioinformatics analysis.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2024.1371990

By:

Mao, Jinlei;
Tao, Yuhang;
Wang, Keke;
Sun, Hanru;
Zhang, Manqi;
Jin, Liang;
Pan, Yi

Publication type:

Article

Extracellular matrix remodeling fibroblasts govern the tumor microenvironment disparity between adenomatous lesions and adenocarcinoma in gallbladder.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1637300

By:

Ma, Chuhan;
Hu, Huixin;
Li, Hanrong;
Han, Bing;
Lv, Chao;
Tian, Yu

Publication type:

Article

Cancer-associated fibroblasts: dual roles from senescence sentinels to death regulators and new dimensions in therapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1635771

By:

Ruan, Guixiang;
Wang, Xiang;
Ou, Huiyi;
Guo, Duancheng

Publication type:

Article

Cancer-associated fibroblasts in hepatocellular carcinoma: origins, heterogeneity, and therapeutic implications.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1620075

By:

Shi, Xin;
Zhu, Weixiong;
Zhang, Jianpeng;
Fan, Chuanlei;
Zhang, Jing

Publication type:

Article

Lentinan enhances CAR-T cell potency in solid tumors by optimizing T cell differentiation.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1605488

By:

Niu, Xiangyun;
Zhang, Pengchao;
Liu, Zhongming;
Tang, Yexiao;
Xu, Shu;
Wan, Xiaochun;
Xu, Zhiming;
Zhang, Guizhong

Publication type:

Article

Research progress on the interaction between glucose metabolic reprogramming and lactylation in tumors.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1595162

By:

Yang, Yi;
Wu, Yi;
Chen, Hui;
Xu, Zehai;
Lu, Ruisi;
Zhang, Sijie;
Zhan, Rui;
Xi, Qinghua;
Jin, Yunfeng

Publication type:

Article

Hes1 in malignant tumors: from molecular mechanism to therapeutic potential.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1585624

By:

Zhang, Liping;
Zhang, Qian;
Guo, Cheng;
Ru, Zixin;
Yang, Zetian;
Geng, Yi;
Yang, Junjie;
Zhang, Daigui;
Yang, Zhenhuai;
Huang, Shuicai

Publication type:

Article

An immunomodulatory photosensitizer-mediated photodynamic therapy synergizes with PD-L1 blockade against metastatic triple-negative breast cancer.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1651165

By:

Liu, Yuetong;
Wang, Liming;
Kong, Feiyan;
Liu, Tianjun;
Liu, Hong

Publication type:

Article

Uncovering the molecular mechanisms of Qingdu Zengye Decoction in the treatment of nasopharyngeal carcinoma: an integrative investigation.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1648294

By:

Quan, Qi;
Liu, Zeyu;
Ding, Ran;
Lin, Yongmiao;
Zhang, Sihe;
Luo, Wei;
Lei, Mengjie;
Fan, Teng;
Su, Xin;
Huang, Yuanyuan;
Peng, Roujun;
Zhang, Bei

Publication type:

Article

The anticancer activity and mechanisms of She medicine herbs.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1610301

By:

Miao, Yunxuan;
Chen, Yisheng;
Lan, Qiaofen;
Chen, Ruogu;
Zhuang, Jiajia;
Shi, Haojun;
Wang, Miao;
Miao, Jianhui;
Lin, Chengshou

Publication type:

Article

"Molecular pigeon" network of lncRNA and miRNA: decoding metabolic reprogramming in patients with lung cancer.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1578927

By:

Li, Mingxiao;
Dai, Ling;
Chen, Simin;
Deng, Minjie;
Wang, Lihuai;
Sun, Yinhui

Publication type:

Article

Unconventional T cells in anti-cancer immunity.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1618393

By:

Laub, Ariel;
Rodrigues de Almeida, Nathalia;
Huang, Shouxiong

Publication type:

Article

From laboratory to clinic: a precise treatment strategy of mesenchymal stem cells-derived exosomes pretreated by simulating disease microenvironment.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1609288

By:

Ye, Hailian;
He, Qi;
Qi, Fang;
Xu, Guangchao;
Qahar, Mulan;
Deng, Chenliang;
Wei, Zairong

Publication type:

Article

Characterization of novel anoikis-related genes as prognostic biomarkers and key determinants of the immune microenvironment in esophageal cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1599171

By:

Su, Yani;
Zhang, Ming;
Xu, Peng;
Wen, Pengfei;
Xu, Ke;
Xie, Jiale;
Wan, Xianjie;
Liu, Lin;
Yang, Zhi;
Yang, Mingyi

Publication type:

Article

Integrative spatial and single-cell transcriptomics elucidate programmed cell death-driven tumor microenvironment dynamics in hepatocellular carcinoma.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1589563

By:

Lei, Kai;
Zhao, Yutong;
Li, Shumin;
Liu, Jiawei;
Chen, Wenhao;
Zhou, Caihong;
Zhang, Yi;
Tan, Jinmei;
Wu, Jian;
Zhou, Qi;
Tan, Jiehui

Publication type:

Article

Harnessing immunotherapy: cancer vaccines as novel therapeutic strategies for brain tumor.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1588081

By:

Kiel, Klaudia;
Piranlioglu, Raziye;
Godlewski, Jakub;
Bronisz, Agnieszka

Publication type:

Article

The immune microenvironment in endometrial carcinoma: mechanisms and therapeutic targeting.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1586315

By:

Wang, Yilin;
Liu, Nana;
Guo, Xiangcui;
Han, Ruobing;
Bai, Jin;
Zhong, Jiateng;
Wang, Qianqing

Publication type:

Article

Effect of TP53 mutation, expression and polymorphism on the survival, immune infiltration and ferroptosis in patients with prostate cancer.

Published in:

Oncology Letters, 2025, v. 30, n. 3, p. N.PAG, doi. 10.3892/ol.2025.15191

By:

Wen, Gui-Min;
Zhao, Zhen-Ying;
Zheng, Xiao-Hui;
Liu, Da-Hua;
Xia, Pu

Publication type:

Article

Risk score model with two immune infiltration-related long non-coding RNAs to predict prognosis in patients with osteosarcoma.

Published in:

Oncology Letters, 2025, v. 30, n. 3, p. N.PAG, doi. 10.3892/ol.2025.15189

By:

Zeng, Ling-Rong;
Zhu, Guang-Hui;
Mei, Hai-Bo;
Yang, Ge

Publication type:

Article