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- Title
Using an age-dependent D-dimer cut-off value increases the number of older patients in whom deep vein thrombosis can be safely excluded.
- Authors
Douma, Renée A; Tan, Melanie; Schutgens, Roger E G; Bates, Shannon M; Perrier, Arnaud; Legnani, Cristina; Biesma, Douwe H; Ginsberg, Jeffrey S; Bounameaux, Henri; Palareti, Gualtiero; Carrier, Marc; Mol, Gerben C; Le Gal, Grégoire; Kamphuisen, Pieter W; Righini, Marc
- Abstract
D-dimer testing to rule out deep vein thrombosis is less useful in older patients because of a lower specificity. An age-adjusted D-dimer cut-off value increased the proportion of older patients (>50 years) in whom pulmonary embolism could be excluded. We retrospectively validated the efficacy of this cut-off combined with clinical probability for the exclusion of deep vein thrombosis.
- Publication
Haematologica, 2012, Vol 97, Issue 10, p1507
- ISSN
1592-8721
- Publication type
Journal Article
- DOI
10.3324/haematol.2011.060657