Works matching DE "DRUG development"

Results: 5000

Moving the needle on immune checkpoint inhibitors with novel targets: are we being TIMid or LAGging behind?

Published in:

Oncologist, 2025, v. 30, n. 7, p. 1, doi. 10.1093/oncolo/oyaf145

By:

Park, Changsu Lawrence;
Bedard, Philippe L

Publication type:

Article

Recaticimab: First Approval.

Published in:

Drugs, 2025, v. 85, n. 8, p. 1067, doi. 10.1007/s40265-025-02199-5

By:

Lamb, Yvette N.

Publication type:

Article

Sipavibart: First Approval.

Published in:

Drugs, 2025, v. 85, n. 8, p. 1049, doi. 10.1007/s40265-025-02186-w

By:

Keam, Susan J.

Publication type:

Article

Limertinib: First Approval.

Published in:

Drugs, 2025, v. 85, n. 8, p. 1055, doi. 10.1007/s40265-025-02184-y

By:

Lee, Arnold

Publication type:

Article

Accelerating the Understanding of Biosensors Through the Lens of Cells: State of the Field, Emerging Directions, Advances, and Challenges.

Published in:

Applied Biochemistry & Biotechnology, 2025, v. 197, n. 7, p. 4224, doi. 10.1007/s12010-025-05209-0

By:

Narang, Jasjeet;
Rana, Niket;
Chauhan, Arjun;
Kumari, Anushka;
Minhas, Vanshika

Publication type:

Article

Efficient and Rapid Arylation of NH₂‐Unprotected Bromobisindole Ethanamines via Suzuki‐Miyaura Coupling: Generating New Leads Against Leishmania.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 43, p. 1, doi. 10.1002/chem.202500637

By:

Buono, Alessandro;
Diotallevi, Aurora;
Maestrini, Sara;
Verboni, Michele;
Kiuru, Paula;
Galluzzi, Luca;
Duranti, Andrea;
Olivieri, Diego;
Lucarini, Simone

Publication type:

Article

Advances and challenges of targeting epicardial adipose tissue (EAT) and perivascular adipose tissue (PVAT).

Published in:

Cardiovascular Diabetology, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12933-025-02763-z

By:

Liu, Dan;
Chen, Wujun;
Guo, Zhu;
Gao, Qun;
Wang, Bin;
Wang, Jie;
Hu, Weichao;
Wang, Chao;
Wang, Shuai;
Wu, Xiaolin;
Xu, Mantao;
Lan, Ganqiu

Publication type:

Article

Genomic characterization and pre-clinical evaluation of a new polyvalent lytic Loughborough phage.

Published in:

Applied Microbiology & Biotechnology, 2025, v. 109, n. 1, p. 1, doi. 10.1007/s00253-025-13559-2

By:

Sherif, Mahmoud M.;
Abdelaziz, Neveen A.;
Saleh, Sarra E.;
Aboshanab, Khaled M.

Publication type:

Article

In silico target identification and pharmacokinetic profiling of 2-aryl-quinoline-4-carboxylic acid derivatives as potential antileishmanial agents.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1621059

By:

da Silva, Marília Cecília;
Viana, Jéssika de Oliveira;
Olegário, Tayná Rodrigues;
Sabino, Jayne Maria;
Barbosa, Euzébio Guimarães;
Chaves, Elton José Ferreira;
Rocha, Gerd Bruno;
Lima-Junior, Claudio Gabriel;
Weber, Karen Cacilda

Publication type:

Article

Preclinical evaluation of dose-dependent effects of photobiomodulation therapy on persistent inflammation in the temporomandibular joint.

Published in:

Journal of Oral & Facial Pain & Headache, 2025, v. 39, n. 2, p. 183, doi. 10.22514/jofph.2025.037

By:

Carvalho, Vinicius Almeida;
Martins, Amanda Almeida;
de Carvalho Desiderá, Amanda;
Nascimento, Glauce Crivelaro;
Magri, Laís Valencise;
Leite-Panissi, Christie Ramos Andrade

Publication type:

Article

Dose-response characterization: A key to success in drug development.

Published in:

Clinical Trials, 2025, v. 22, n. 4, p. 384, doi. 10.1177/17407745251350289

By:

Bretz, Frank;
Bornkamp, Björn;
Dumortier, Thomas

Publication type:

Article

Comparison of adaptive seamless Phase 2/3 designs for dose selection in clinical trials with multiple endpoints.

Published in:

Clinical Trials, 2025, v. 22, n. 4, p. 405, doi. 10.1177/17407745251338592

By:

Jin, Man

Publication type:

Article

Military influences on the evolution of clinical trials throughout history.

Published in:

Clinical Trials, 2025, v. 22, n. 4, p. 501, doi. 10.1177/17407745241309054

By:

Malshy, Kamil;
Steinmetz, Alexis;
Yuen, Kit;
Bandari, Jathin;
Rabinowitz, Ronald

Publication type:

Article

New opportunities and current challenges using animal models for the discovery of novel countermeasures for acute radiation syndrome.

Published in:

Expert Opinion on Drug Discovery, 2025, v. 20, n. 8, p. 1045, doi. 10.1080/17460441.2025.2528966

By:

Singh, Vijay K.;
Seed, Thomas M.

Publication type:

Article

Synthesis, molecular modeling and harnessing the antimicrobial activity of new pyrazine-thiadiazole hybrids.

Published in:

BMC Chemistry, 2025, v. 19, n. 1, p. 1, doi. 10.1186/s13065-025-01587-y

By:

Abumelha, Hana M.;
Halawani, Nuha M.;
Alharbi, Abdulrahman S.;
Alsulami, Rabah N.;
Qurban, Jihan;
Alomari, Khadra B.;
Al-Bonayan, Ameena M.;
El-Metwaly, Nashwa

Publication type:

Article

Structure-based virtual screening, molecular docking, and MD simulation studies: An in-silico approach for identifying potential MBL inhibitors.

Published in:

PLoS ONE, 2025, v. 20, n. 7, p. 1, doi. 10.1371/journal.pone.0324836

By:

Noumi, Emira;
Snoussi, Mejdi;
Bouali, Nouha;
Alshammari, Mamdouh M.;
Altayb, Hisham N.;
Afzal, Muhammad;
De Feo, Vincenzo

Publication type:

Article

Obesity: A Persistent Puzzle-Unveiling Past Missteps and Future Promise in Drug Discovery.

Published in:

Karbala Journal of Pharmaceutical Sciences, 2024, v. 15, n. 25, p. 149, doi. 10.62472/kjps.v15.i25.149-174

By:

AlKhafaji, Sura L.;
Al-Owaidi, Mohammed Fanokh

Publication type:

Article

Hybrids of 4-aminoquinolines and adamantane as inhibitors of AChE.

Published in:

Journal of the Serbian Chemical Society, 2025, v. 90, n. 5, p. 545, doi. 10.2298/JSC250131014K

By:

KOMATOVIĆ, KATARINA;
MATOŠEVIĆ, ANA;
ZLATOVIĆ, MARIO;
SLADIĆ, DUŠAN;
BOSAK, ANITA;
OPSENICA, DEJAN M.

Publication type:

Article

Optimal Design of Drug–Drug Interaction Studies for the GLP‐1 Receptor Agonist Drug Class for Weight Management: Closing a Potential Data Gap.

Published in:

Journal of Clinical Pharmacology, 2025, v. 65, n. 8, p. 1056, doi. 10.1002/jcph.70020

By:

Weber, Elijah;
Trivedi, Ashit;
Barbour, April M.

Publication type:

Article

Dose Ranging in Pediatric Drug Development Trials Submitted to the US FDA 2012–2020.

Published in:

Journal of Clinical Pharmacology, 2025, v. 65, n. 8, p. 955, doi. 10.1002/jcph.70016

By:

Lee, Carlton K. K.;
Kwon, Eugenia;
Green, Francis G.;
Kelley, Connor M. I.;
Pham, Jennifer;
Abulwerdi, Gelareh;
Samuels, Sherbet;
Green, Dionna J.;
Burckart, Gilbert J.

Publication type:

Article

A Physiologically Based Pharmacokinetic Model of an Oral Tyrosine Kinase 2 Inhibitor Deucravacitinib in Healthy Adults.

Published in:

Journal of Clinical Pharmacology, 2025, v. 65, n. 8, p. 1011, doi. 10.1002/jcph.70014

By:

Chen, Xinyue;
Lin, Zhoumeng

Publication type:

Article

The 2015 Nobel Prize Laureates in Physiology or Medicine.

Published in:

Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journal of Serbia, 2015, v. 72, n. 11, p. 951, doi. 10.2298/VSP1511951M

By:

Mikić, Dragan

Publication type:

Article

The first pharmacy in Vranje with the educated pharmacist and its development.

Published in:

Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journal of Serbia, 2014, v. 71, n. 10, p. 978, doi. 10.2298/VSP130819048K

By:

Krajnović, Dušanka M.;
Arsić, Jasmina B.;
Milošević Georgijev, Andrijana M.;
Manojlović, Jelena M.

Publication type:

Article

Patent law protection of inventions in medicine and pharmaceutical industry.

Published in:

Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journal of Serbia, 2013, v. 70, n. 6, p. 600, doi. 10.2298/VSP1306600M

By:

Miladinović, Zoran;
Varga, Siniša;
Radojković, Marija

Publication type:

Article

Phenotyping Before Starting Treatment in COPD?

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2017, v. 14, n. 3, p. 367, doi. 10.1080/15412555.2017.1303041

By:

Siafakas, Nikolaos;
Corlateanu, Alexandru;
Fouka, Evangelia

Publication type:

Article

The COPD Pipeline XXIV.

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2013, v. 10, n. 5, p. 625, doi. 10.3109/15412555.2013.832093

By:

Gross, Nicholas J.

Publication type:

Article

The COPD Pipeline XXIII.

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2013, v. 10, n. 4, p. 545, doi. 10.3109/15412555.2013.811988

By:

Gross, Nicholas

Publication type:

Article

The COPD Biomarker Qualification Consortium (CBQC).

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2013, v. 10, n. 3, p. 367, doi. 10.3109/15412555.2012.752807

By:

Casaburi, Richard;
Celli, Bartolome;
Crapo, James;
Criner, Gerard;
Croxton, Thomas;
Gaw, Alasdair;
Jones, Paul;
Kline-Leidy, Nancy;
Lomas, David A.;
Merrill, Debora;
Polkey, Michael;
Rennard, Stephen;
Sciurba, Frank;
Tal-Singer, Ruth;
Stockley, Robert;
Turino, Gerry;
Vestbo, Jorgen;
Walsh, John

Publication type:

Article

Patient-reported Outcome (PRO) Measures for Clinical Trials of COPD: The EXACT and E-RS.

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2013, v. 10, n. 3, p. 393, doi. 10.3109/15412555.2013.795423

By:

Leidy, Nancy K.;
Murray, Lindsey T.

Publication type:

Article

The COPD Pipeline XXI.

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2013, v. 10, n. 2, p. 266, doi. 10.3109/15412555.2013.771023

By:

Gross, Nicholas

Publication type:

Article

The COPD Pipeline XX.

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2013, v. 10, n. 1, p. 104, doi. 10.3109/15412555.2013.766103

By:

Gross, Nicholas

Publication type:

Article

The COPD Pipeline XVI.

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2012, v. 9, n. 3, p. 310, doi. 10.3109/15412555.2012.683968

By:

Gross, Nicholas;
Mann, Marianne

Publication type:

Article

The COPD Pipeline XV.

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2012, v. 9, n. 2, p. 203, doi. 10.3109/15412555.2012.665756

By:

Gross, Nicholas

Publication type:

Article

Knowledge-driven approaches for the guidance of first-in-children dosing.

Published in:

Pediatric Anesthesia, 2011, v. 21, n. 3, p. 206, doi. 10.1111/j.1460-9592.2010.03473.x

By:

Edginton, Andrea N.

Publication type:

Article

Role of modeling and simulation in pediatric investigation plans.

Published in:

Pediatric Anesthesia, 2011, v. 21, n. 3, p. 214, doi. 10.1111/j.1460-9592.2011.03523.x

By:

Manolis, Efthymios;
Osman, Tariq Eldirdiry;
Herold, Ralf;
Koenig, Franz;
Tomasi, Paolo;
Vamvakas, Spiros;
Raymond, Agnes Saint

Publication type:

Article

Emerging pharmacological agents for post-traumatic stress disorder show promise, but more evidence is needed.

Published in:

Drugs & Therapy Perspectives, 2024, v. 40, n. 12, p. 479, doi. 10.1007/s40267-024-01123-3

By:

Zhuang-Yan, Amy

Publication type:

Article

Sovateltide in cerebral ischaemic stroke: a profile of its use.

Published in:

Drugs & Therapy Perspectives, 2024, v. 40, n. 7, p. 250, doi. 10.1007/s40267-024-01094-5

By:

Fung, Simon;
Syed, Yahiya Y.

Publication type:

Article

Many drugs are available for hypertension, with more in development.

Published in:

Drugs & Therapy Perspectives, 2022, v. 38, n. 12, p. 520, doi. 10.1007/s40267-022-00951-5

By:

Lee, Arnold

Publication type:

Article

UNTANGLING THE ORIGINS OF COMPETITIVE ADVANTAGE.

Published in:

Strategic Management Journal (Wiley-Blackwell) - 1980 to 2009, 2000, v. 21, n. 10/11, p. 1123, doi. 10.1002/1097-0266(200010/11)21:10/11<1123::AID-SMJ130>3.0.CO;2-R

By:

Cockburn, Iain M.;
Henderson, Rebecca M.

Publication type:

Article

The Prolegomena to Sābūr Ibn Sahl's Small Dispensatory*.

Published in:

Journal of Semitic Studies, 2012, v. 57, n. 1, p. 145, doi. 10.1093/jss/fgr037

By:

Kahl, Oliver

Publication type:

Article

National and International Tests of the New Drug Cost Offset Theory.

Published in:

Southern Economic Journal, 2011, v. 77, n. 4, p. 1033, doi. 10.4284/0038-4038-77.4.1033

By:

Santerre, Rexford E.

Publication type:

Article

Discovery of Galangin Derivatives as a Potential T-cell Leukemia Virus 1 Protease Inhibitor Through Chemoinformatics Approaches.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 2, p. 2067, doi. 10.1007/s12013-024-01618-w

By:

Akash, Shopnil;
Sultana, Sharifa;
Islam, Mirza Nafeul;
Or Rashid, Md. Harun;
Oduselu, Gbolahan Oladipupo;
Kaouche, Farah Chafika;
Sindi, Emad Rashad;
de Farias Morais, Gabriel Christian;
Al-Dies, Al-Anood M.;
Oliveira, Jonas Ivan Nobre

Publication type:

Article

Flavonoids of Euphorbia hirta inhibit inflammatory mechanisms via Nrf2 and NF-κB pathways.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 1, p. 1167, doi. 10.1007/s12013-024-01551-y

By:

Bai, Xiaolin;
Li, Lijun;
Wu, Yuning;
Jie, Bai

Publication type:

Article

Correction: In Silico Exploration of Isoxazole Derivatives of Usnic Acid: Novel Therapeutic Prospects Against α-Amylase for Diabetes Treatment.

Published in:

2025

By:

Roney, Miah;
Issahaku, Abdul Rashid;
Huq, A. K. M. Moyeenul;
Sapari, Suhaila;
Abdul Razak, Fazira Ilyana;
Wilhelm, Anke;
Zamri, Normaiza Binti;
Sharmin, Sabrina;
Islam, Md. Rabiul;
Mohd Aluwi, Mohd Fadhlizil Fasihi

Publication type:

Correction Notice

Exploring the Anticancer Potential of Furanpydone A: A Computational Study on its Inhibition of MTHFD2 Across Diverse Cancer Cell Lines.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 1, p. 437, doi. 10.1007/s12013-024-01474-8

By:

Alhawarri, Maram B.

Publication type:

Article

An Update on the Pharmacological Usage of Curcumin: Has it Failed in the Drug Discovery Pipeline?

Published in:

Cell Biochemistry & Biophysics, 2020, v. 78, n. 3, p. 267, doi. 10.1007/s12013-020-00922-5

By:

Olotu, Fisayo;
Agoni, Clement;
Soremekun, Opeyemi;
Soliman, Mahmoud E. S.

Publication type:

Article

Human Airway Primary Epithelial Cells Show Distinct Architectures on Membrane Supports Under Different Culture Conditions.

Published in:

Cell Biochemistry & Biophysics, 2016, v. 74, n. 2, p. 191, doi. 10.1007/s12013-016-0719-8

By:

Min, Kyoung;
Rosania, Gus;
Shin, Meong

Publication type:

Article

Biological Evaluation of Endophytic Fungus, Chaetomium globosum JN711454, as Potential Candidate for Improving Drug Discovery.

Published in:

Cell Biochemistry & Biophysics, 2014, v. 68, n. 1, p. 67, doi. 10.1007/s12013-013-9695-4

By:

Selim, Khaled;
El-Beih, Ahmed;
Abdel-Rahman, Tahany;
El-Diwany, Ahmed

Publication type:

Article

Ubiquitin and Drug Discovery: Challenges and Opportunities.

Published in:

2013

By:

Weissman, Allan

Publication type:

Editorial

Deubiquitylating Enzymes and DNA Damage Response Pathways.

Published in:

Cell Biochemistry & Biophysics, 2013, v. 67, n. 1, p. 25, doi. 10.1007/s12013-013-9635-3

By:

Jacq, Xavier;
Kemp, Mark;
Martin, Niall;
Jackson, Stephen

Publication type:

Article