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- Title
Anaplasma phagocytophilum from Rodents and Sheep, China.
- Authors
Lin Zhan; Wu-Chun Cao; Jia-Fu Jiang; Xiao-Ai Zhang; Yun-Xi Liu; Xiao-Ming Wu; Wen-Yi Zhang; Pan-He Zhang; Chang-Ling Bian; Dumler, J. Stephen; Hong Yang; Shu-Qing Zuo; Chen-Yi Chu; Wei Liu; Richardus, Jan H.; Habbema, J. Dik F.
- Abstract
To characterize the strains of Anaplasma phagocytophilum in wild and domestic animals in China, we isolated the organism from rodents and sheep in northeastern China. We isolated 3 strains (2 from rodents and 1 from sick sheep) through propagation in BALB/c mice and then cell culture in HL60 cells. The 3 isolates were identified by Wright-Giemsa staining, immunofluorescence, and electronic microscopy and were characterized by sequence analyses of the 16S rRNA gene, partial citrate synthase gene, major surface protein 4 gene, and heat shock protein gene. The multiple sequences of the 3 isolates were identical to each other but different from all known strains from other countries. The public health and veterinary relevance of the isolates deserves further investigation.
- Publication
Emerging Infectious Diseases, 2010, Vol 16, Issue 5, p764
- ISSN
1080-6040
- Publication type
Academic Journal
- DOI
10.3201/eid1605.091293