We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Severe community-acquired pneumonia due to Staphylococcus aureus, 2003-04 influenza season.
- Authors
Hageman, Jeffrey C; Uyeki, Timothy M; Francis, John S; Jernigan, Daniel B; Wheeler, J Gary; Bridges, Carolyn B; Barenkamp, Stephen J; Sievert, Dawn M; Srinivasan, Arjun; Doherty, Meg C; McDougal, Linda K; Killgore, George E; Lopatin, Uri A; Coffman, Rebecca; MacDonald, J Kathryn; McAllister, Sigrid K; Fosheim, Gregory E; Patel, Jean B; McDonald, L Clifford
- Abstract
During the 2003-04 influenza season, 17 cases of Staphylococcus aureus community-acquired pneumonia (CAP) were reported from 9 states; 15 (88%) were associated with methicillin-resistant S. aureus (MRSA). The median age of patients was 21 years; 5 (29%) had underlying diseases, and 4 (24%) had risk factors for MRSA. Twelve (71%) had laboratory evidence of influenza virus infection. All but 1 patient, who died on arrival, were hospitalized. Death occurred in 5 (4 with MRSA). S. aureus isolates were available from 13 (76%) patients (11 MRSA). Toxin genes were detected in all isolates; 11 (85%) had only genes for Panton-Valentine leukocidin. All isolates had community-associated pulsed-field gel electrophoresis patterns; all MRSA isolates had the staphylococcal cassette chromosome mec type IVa. In communities with a high prevalence of MRSA, empiric therapy of severe CAP during periods of high influenza activity should include consideration for MRSA.
- Publication
Emerging infectious diseases, 2006, Vol 12, Issue 6, p894
- ISSN
1080-6040
- Publication type
Journal Article
- DOI
10.3201/eid1206.051141