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- Title
Hepatitis C virus infection, Linxian, China.
- Authors
Zhang, Mingdong; Sun, Xiu-Di; Mark, Steven D; Chen, Wen; Wong, Lara; Dawsey, Sanford M; Qiao, You-Lin; Fraumeni, Joseph F, Jr; Taylor, Philip R; O'Brien, Thomas R
- Abstract
Bloodborne viruses may have spread in rural China during the past 25 years, but population-based prevalence estimates are lacking. We examined the frequency of hepatitis C virus (HCV) and HIV type 1 (HIV-1) among residents of Linxian, a rural community in Henan Province. In 2000, blood was collected from participants (> or = 55 years of age) who had enrolled in a population-based nutritional intervention trial in 1985. We randomly selected 500 participants for HCV testing and 200 participants for HIV-1 testing. For HCV, 48 (9.6%) of 500 participants were positive by enzyme immunoassay and recombinant immunoblot assay (95% confidence interval, 7.0%-12.2%), and prevalence was lowest in the most geographically isolated participants. Among the HCV-infected participants, 42 had a specimen available from 1985, of which 16 (38.1%) were positive for HCV. For HIV-1, 0/200 participants were positive. We conclude that HCV is now a common infection among older adults in Linxian, China.
- Publication
Emerging infectious diseases, 2005, Vol 11, Issue 1, p17
- ISSN
1080-6040
- Publication type
Journal Article
- DOI
10.3201/eid1101.031005