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Title: Antibacterial evaluation of some new benzimidazole derivatives.
Authors: MAHMOUD, MUHANNED A.; IBRAHIM, SURA K.; RDAIAAN, MUAYAD AHMED
Abstract: In this study, we synthesized a sequence of benzimidazole compounds containing. 1,3,4-thiadiazole ring and azo moiety from many reaction steps. The obtained benzimidazole series had been categorized by their melting point, FT-IR and 1H-NMR data and exhibited good pharmacological activities upon in vitro screening for the antibacterial activitiesin contrast to strains of selection of pathogenic Gram-positive bacteria (S. aureus and B. subtilis) and Gramnegative bacteria (E.coliand p. aeruginosa) in comparison with (Amoxicillin) and (Ciprofloxacin) as standard antibacterial agents.
Subjects: BENZIMIDAZOLES; THIADIAZOLES; AZO compounds; ANTIBACTERIAL agents; PATHOGENIC microorganisms
Publication: International Journal of Pharmaceutical Research (09752366), 2020, Vol 12, Issue 1, p282
ISSN: 0975-2366
Publication type: Academic Journal
DOI: 10.31838/ijpr/2020.12.01.050

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Antibacterial evaluation of some new benzimidazole derivatives.