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- Title
Marked effect and steroid-sparing ability of anakinra on a patient with refractory adult-onset Still’s disease.
- Authors
Tamaki, Hiromichi; Shimizu, Hisanori; Hiraoka, Eiji; Uechi, Eishi; Kishimoto, Mitsumasa; Yamaguchi, Kenichi; Okada, Masato
- Abstract
We report a case of refractory adult-onset Still’s disease (AOSD) successfully controlled with anakinra, an interleukin-1 (IL-1) receptor antagonist. The patient was a 23-year-old Japanese woman with AOSD who could not be induced into remission despite of two courses of pulsed methylprednisolone followed by high-dose glucocorticoid administration in conjunction with high-dose intravenously administered γ-globulin and methotrexate. To the best of our knowledge, this is the first case report in Japan of AOSD remission induced with anakinra.
- Publication
Modern Rheumatology, 2010, Vol 20, Issue 2, p200
- ISSN
1439-7595
- Publication type
Academic Journal
- DOI
10.3109/s10165-009-0254-1